Infection of renal cysts in polycystic kidney disease is a severe complication of
ADPKD, potentially resulting in abscess, sepsis, and death. The diagnosis of
cyst infection difficult because of non-specific signs and symptoms as well as
limitation of conventional ultrasound and CT imaging.
In clinical practice, the criteria of cysts infection diagnosis may include
as below:
▪ Infected cysts are considered as definite in the presence of a cyst
aspiration showing evidence of infection(neutrophils debris and/or
microorganism);
▪ Features that figure the possibility of infected cysts include:
fever (T>38.5°C for more than 3 days), abdominal pain, increased
C-reactive protein (CRP; >50 mg/L), and the absence of any significant recent
intracystic bleeding or other causes of fever.
▪ Positive result of kidney and liver ultrasound date when debris with a
thick wall and/or a distal acoustic enhancement in at least a cyst;
▪ Positive kidney and liver CT and MRI data when enhance a thick wall and/or
detection of perilesional inflammation in at least a cyst.
What are treatment for infected cysts due to ADPKD?
Antibiotic treatment modification is more frequently adopted for people who
are receive initial monotherapy compared with those who are receive
bitherapy.
Persistent or recurrent large (diameter>5cm) infected cysts often require
drainage by surgical procedures. Drainage is appropriate in some times with an
infected cyst. However, this is very temporary, the drained cysts refill quickly
and any pain relief is transient at best.
As one of the largest kidney disease hospital around the world, we have more
than 20 years' experience and expertise in PKD treatment. If you or your beloved
one is diagnosed with Adult PKD, we're here to help. Call +86 311 8926-1580 or
consult our online service if you have any questions about the disease.
