2017年5月4日星期四

How Is the Prognosis of Stage 3 Diabetic Nephropathy

Stage 3 is a watershed for the progression of Diabetic Nephropathy. If the patients can receive proper treatment, the disease can be reversed. If left untreated, it will develop into ESRD in a short time. So, how to improve its prognosis and stop its progression?

In stage 3, the albumin in urine increases obviously and blood pressure begins to rise. These are two factors in aggravating renal function. To minimize their influence on prognosis of Diabetes, the patients should adopt the following measures:

1. Control blood glucose level strictly.

2. No matter the patients have high blood pressure or not, they should be recommended to use ACEI or ARB to prevent blood pressure rising. If high blood pressure has occurred, they should take some other medications along with ACEI and ARB to control blood pressure below 130/80 mmHg.

3. To reduce albumin leakage, the patients should reduce the protein intake and restrict its intake to 0.8 grams/kg per body weight per day.

4. If edema occurs, they should limit salt intake less than 3 grams per day.

The above measures matter a lot in improving prognosis of Diabetic Nephropathy. However, they are not enough to stop the disease progression at all. Immunotherapy has been applied to restore impaired kidneys and improve renal function and has showed a remarkable therapeutic effect.

Immunotherapys are unspecialized cells with potentials of differentiation and self-renewing. They are ideal seed cells and can restore impaired organs and tissues.

After they are injected into the patients’ body, the injured sites release signals to attract the Immunotherapy to travel there. Stimulated by the injured cells and environment, the Immunotherapy will differentiate into new cells. With development, the new cells will become specialized to transform into new kidney tissues and blood vessels.

Finally, the kidneys will be restored very well and the patients will get rid of the risk of ESRD, dialysis or kidney transplant.

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