The prognosis of Lupus Nephritis may vary from case to case because many
factors can affect the progression of the disease. Generally speaking, the
following factors will worsen Lupus Nephritis.
⑴ Infection
Preventing infections such as colds play a very important role in improving
the patients’ survival.
In Lupus Nephritis, the renal functional cells are damaged severely. If there
is infection in body, the impaired cells will attract the inflammatory factors
thus causing more damage to them.
⑵ Lupus activity
If lupus is not controlled effectively, it will bring more damage to kidneys
and other organs and tissues. The following factors may trigger the lupus
activity:
Exposure to sunlight for a long time
Infections
Foods that can cause allergic response
Pregnancy
⑶ Frequent relapses
Every relapse is a big trauma to kidneys and will cause violent inflammatory
response in glomeruli. If the disease relapses quite frequently, it will develop
into Renal Failure in a short time.
However, hormone and immunosuppressive agents only can relieve the symptoms
of Lupus Nephritis and suppress the inflammatory response temporarily. As it can
not eliminate its root causes, the disease is at high risk of relapsing.
⑷ Complications of Lupus Nephritis
Proteinuria is a risky factor in aggravating renal function. Proteinuria has
toxityand it can cause damage to mesangial cells and cause matrix svnthesis thus
accelerating the glomerulosclerosis.
High blood pressure can damage the kidney capillaries and improve their
permeability. In return, it can promote the protein leakage significantly.
The above article has introduced the factors which can worsen Lupus
Nephritis. If the patients can avoid those factors, they will get a favorable
prognosis.
Meanwhile, if the patients can receive effective treatment, they will be able
to stop the disease progression. In our hospital, the latest
therapy—immunotherapy is applied to treat Lupus Nephritis and has showed a
remarkable curative effect.
It aims at regulating the autoimmune process to stop the attack to
glomeruli.
It controls the symptoms by restoring the impaired glomeruli.
It is a combination therapy of natural therapy and biotherapy so it does not
have side effects on body.
