Treatment of membranoproliferative glomerulonephritis in type 3
Membranoproliferative glomerulonephritis (MPGH) is a kind of glomerulonephritis with inflammation of glomeruli or kidney filters. It can be divided into three subtypes in histology. What is the treatment of IGOS in the 3rd type?
Type 3 IGPN is an immuno-mediated disease with immune complexes in the glomerular subepithelial space. In a normal state, when external harmful substances invade the body, antibodies are activated by the immune system to destroy harmful substances called antigens. However, with an immune disorder, the immune system can not explain the difference between foreign substances and healthy kidney cells. Antibodies combine with antigens to form immune complexes. When immune complexes precipitate in the kidneys, it can lead to inflammation. Uncontrolled inflammation can lead to a progressive decrease in kidney function.
What is the treatment of membrane-proliferative glomerulonephritis in type 3?
IGNA in the 3 rd type is usually associated with many other diseases or disorders, including autoimmune diseases, chronic infections, etc. It is usually solved by the successful treatment of associated conditions and diseases. However, there is no good treatment for idiopathic IGOS in conventional treatment.
Immunosuppressive drugs can suppress the abnormal reaction of the immune system and reduce the immune damage to the kidneys. Steroids can relieve inflammation of the kidneys and proteinuria. However, long-term use of these drugs can cause a large number of side effects. In addition, these drugs alone can not stop the progression of the disease at all.
What is the last treatment for membrane-proliferative glomerulonephritis in type 3?
As mentioned above, IGOS is an immuno-mediated disorder. Immunotherapy is known as the last treatment for MPGN type 3. It is used to treat various refractory diseases and conditions. In the treatment of immune-mediated renal disease, it works as follows. First, it can control inflammation in the kidneys and stop more immune damage to the kidneys. Secondly, it can help the body restore the normal immune system and restore immunity. Thus, the disease will be completely prevented. Thirdly, by stimulating the self-healing system of the body, damaged kidney tissues can be regenerated. Thus, the renal function will be significantly improved. Still there are Chinese medicine too, can help patients, like osmotherapy of micro-Chinese medicine, foot bath, etc.
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