Polycystic kidney disease presentation and associated test checks

Polycystic Kidney Disease (PKD) is genetic condition in which multiple fluid-filled sacs or cysts develop throughout the kidneys. There are two types: 90% of people with PKD have autosomal dominant polycystic kidney disease (ADPKD), or adult PKD. The remaining 10% have autosomal recessive polycystic kidney disease (ARPKD), which affects infants and children.
When making a Polycystic Kidney Disease diagnosis, the doctor may ask a number of questions associated with the medical history, other medical conditions you may have and whether you have a family history of any conditions, including PKD. Besides, certain tests can be performed to detect the size and number of kidney cysts as well as evaluate the kidney function.
● Ultrasound examination
This is a common in the medical diagnostic method, using sound waves to create a picture out of a kidney condition. Injection ultrasound imaging does not use any dye or radiation, so for all patients, including pregnant women is safe.
● Other imaging tests
More powerful and expensive imaging procedures, such as computed tomography (CT scan) and magnetic resonance imaging (MRI), can also detect cysts. Recently, MRI has been used to measure kidney and cyst volume and monitor kidney and cyst growth, which may serve as a way to track progression of the disease.
● Genetic testing
This test can help us detect mutations in the autosomal dominant PKD genes, called PKD1 and PKD2. However, its usefulness is limited by two factors; it cannot predict the onset of symptoms or ultimate severity of the disease, and no specific prevention or cure of the disease is available. On the other hand, this test can help a young person detect the gene mutation, so he may be able to prevent the disease through diet and blood pressure control.
Polycystic kidney disease is more than just a simple introduction, if you have this disease there is more you want to know something, you can click on more of our articles, or send your finishing down the case, there is Email kidney-support@hotmail.com, within 12 hours we will give you a professional guidance answer.

Polycystic kidney disease hazards and related complications

Polycystic Kidney Disease (PKD) is a genetic condition in which many cysts form in the kidneys, eventually affecting the ability of the kidneys to function. Depending on the type of PKD, symptoms often begin either in early adulthood, between the ages of 30~40 years, or in infancy or early childhood. Both men and women of all races are likely to be affected equally.So, what are the complications of polycystic kidney disease do? Have much impact?

Ⅰ. High blood pressure (hypertension)
This occurs in about 60% to 70% of people with PKD and for many is the first sign of the disease. Due to the presence and gradual enlargement of multiple cysts, the normal kidney structure is altered. Consequently, the kidney function of monitoring blood volume is disturbed and more renin is secreted, causing elevated level of blood pressure.
Ⅱ. Urinary tract infection (UTI)
UTI is common among people with PKD, which include cystitis, pyelonephritis, infection of cyst and perinephric abscess. For female patients, urinary tract examination is one of the risk factors, because while doing it, equipments may lead to infection in urinary tract.
Ⅲ. Decline in kidney function
Cysts in the kidney which more serious, as the occurrence of this phenomenon, renal cells and tissue damage, resulting in decreased renal function. Once the progression to end-stage, the patient had to undergo dialysis or a kidney transplant.
Ⅳ. Kidney stones
About 20% to 30% of people with PKD develop kidney stones. They usually suffer from dull pain in the renal region. If there is colic or sharp pain as well as gross hematuria, it may indicate the appearance of kidney stones.
Ⅴ. Cysts in other parts of the body
Although the kidneys are the main site affected, cysts may also develop in other parts of the body, such as the liver, pancreas, seminal vesicles, and the arachnoid membrane (tissue next to the brain).
Polycystic kidney disease is more than just a simple introduction, if you have this disease there is more you want to know something, you can click on more of our articles, or send your finishing down the case, there is Email kidney-support@hotmail.com, within 12 hours we will give you a professional guidance answer.