2015年7月26日星期日

Can I live with PKD: Diabetes, hard breath, creatine 3.9

Here is a letter reply for a Polycystic Kidney Disease (PKD) patient from German, who suffers from diabetes and hard breath, as well as poor kidney functions.

Q: Upto date I have been treated by 6 to 9 doctors and everybody advises me that there is no medicine to cure or control the growth of cysts. Cause of PKD, I also have diabetes and breathing problems. As I can’t take any healthy foods I am feeling weak and finds hard to breath sometimes. My latest blood reports indicate that my urea is 67 and creatinine is 3.9.

A: As PKD is a genetic disease, it is really hard to cure this problem. PKD damages kidney through cystic pressure to normal functional kidney cells and lead to renal anemia, so if kidney cysts can be shrunk, together with proper treatments for protection, PKD can still be controlled well.

For your present condition, kidneys are enlarged and creatinine level is high. Frankly, the remaining overall kidney function could not be more than 25%. For your present condition, the priority is to successfully block any further kidney function decline through shrinking these cysts and promoting blood flow into kidneys.

For your present condition, and if analyzed from cytology, there are three types of cells in your kidneys. There are healthy functional cells, damaged cells and necrotic cells. Healthy cells are working excessively, and if checked by Biopsy, we can find these cells are enlarged. Long term overloaded station makes them fragile to any external influence like infection. And this is the reason why some patient with stable condition may experience sharp kidney function decline after an infection like serious cold.

As to these damaged cells, they are still working but partial incapability, and they are on the road of becoming necrotic. As to these necrotic cells, frankly speaking, there is no method to restore their function. Treatment for kidney failure should be a holistic treatment that alleviates internal influence to provide a favorable environment for the recuperation and self-repairing of these overloaded and damaged cells, and the treatment should also replenish the absolute number of functioning kidney cells.


As there is still certain remaining kidney function, there is still a great hope to block this progression.

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