2015年7月13日星期一

Congenital Cystic Kidney Disease: Cause, Symptoms, Treatment, Facts

Cystic Kidney Disease is divided into kidney cysts and polycystic kidney disease. As the later one is a genetic disorder, it is also known as congenital cystic kidney disease.

Cause

Congenital cyst kidney disease is expressed as both a recessive and dominant trait. The recessive genetic trait needs both parents affected with PKD genes and there is a possibility for their children to get the recessive PKD. People with autosomal polycystic kidney disease are common and can be inherited from just one parent.

Symptoms

As PKD becomes more advanced, the kidney’s inability to function properly becomes more pronounced. Patients with this congenital have a much higher rate of kidney stones, liver cyst, pancreas. Other symptoms may include insufficient supply of oxygen and blood, enlarged heart, blood in urine, high blood pressure, even aneurysms. Other health problems associated with adult onset PKD include: chronic leg or back pain; frequent infections; and herniations of the groin and abdomen.

Treatment

If adult PKD is diagnosed before symptoms become evident, urinalysis and other diagnostic tests are performed at six-week intervals to monitor the patient's health status.

If results indicate the presence of infection or another PKD-related health problem, aggressive antibiotic therapy is initiated to prevent inflammation that can accelerate disease progression. And surgery may be needed to drain cysts that bleed, cause pain, have become infected, or interfere with normal kidney function
Lowering high blood pressure can slow loss of kidney function. Blood-pressure control, which is the cornerstone of PKD treatment, is difficult to achieve.

Shrinking renal cysts can prevent the further damages. To achieve the goal, surgery and Chinese herbs are suggested.

If you develop into kidney failure stage, Immunotherapy can be used to improve your kidney functions.

Facts

● Over 600,000 Americans are affected with polycystic kidney disease (PKD).

● Hypertension occurring in 50 to 70 percent of cases before any significant reduction in glomerular filtration rate within an average age onset of 30 years of age.

● If you have PKD1 kidney failure usually happens in your 50s where PKD2 failure usually happens in your 70s and sometimes not at all.


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