Symptoms of Infected Cysts Due to ADPKD

Infection of renal cysts in polycystic kidney is a severe complication of ADPKD, potentially resulting in abscess, sepsis, and death. The diagnosis of cyst infection difficult because of non-specific signs and symptoms as well as limitation of conventional ultrasound and CT imaging.

In clinical practice, the criteria of cysts infection diagnosis may include as below:

▪ Infected cysts are considered as definite in the presence of a cyst aspiration showing evidence of infection(neutrophils debris and/or microorganism);

▪ Features that figure the possibility of infected cysts include:

fever (T>38.5°C for more than 3 days), abdominal pain, increased C-reactive protein (CRP; >50 mg/L), and the absence of any significant recent intracystic bleeding or other causes of fever.

▪ Positive result of kidney and liver ultrasound date when debris with a thick wall and/or a distal acoustic enhancement in at least a cyst;

▪ Positive kidney and liver CT and MRI data when enhance a thick wall and/or detection of perilesional inflammation in at least a cyst.

What are treatment for infected cysts due to ADPKD?

Antibiotic treatment modification is more frequently adopted for people who are receive initial monotherapy compared with those who are receive bitherapy.

Persistent or recurrent large (diameter>5cm) infected cysts often require drainage by surgical procedures. Drainage is appropriate in some times with an infected cyst. However, this is very temporary, the drained cysts refill quickly and any pain relief is transient at best.

As one of the largest kidney disease hospital around the world, we have more than 20 years' experience and expertise in PKD treatment. If you or your beloved one is diagnosed with Adult PKD, we're here to help. Consult our online service if you have any questions about the disease.

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