2016年9月28日星期三

Some Questions of Polycystic Kidney Disease

Ⅰ.How does PKD treatment develop?

The reason why Polycystic Kidney Disease patients have higher serum creatinine is that patients’ cysts growing bigger gradually, which canl damage renal inherent cells, start the process of renal fibrosis and aggravate inherent cells injury furthrt. Damaged inherent cells can shrink blood vessel, which can cause High Blood Pressure. Because epithelial cells in inherent cells get damaged, they can’t prevent blood protein leakage,and then Albuminuria occurs. When inherent cells are so injured that they can not excrete more toxins, serum creatinine increases.

Ⅱ.What is the key point of causing Polycystic Kidney Disease?

Inherent cells injury caused by renal fibrosis is the real cause of Polycystic Kidney Disease. High Blood Pressure, Proteinuria, Blood Urine caused by inherent cells injury are symptoms of this disease. If patients want to cure High Blood Pressure, Proteinuria, Blood Urine, they need to cure real cause of this disease firstly.

No matter what kinds of therapeutic methods are taken, real cause of Polycystic Kidney Disease should be treated firstly. Treating disease must block Renal Fibrosis which can damage renal inherent cells. As long as the process of renal fibrosis is blocked and damaged inherent cells get repaired, symptoms of Albuminuria and Haematuria can disappear and cysts can be shrunk gradually.

The reason why disease continues for a long term is that effective treatment is not taken to block Renal Fibrosis.So the real reason why disease can’t be cured is that medicine can’t prevent the renal fibrosis from damaging renal inherent cells.

Ⅲ.How to treat Polycystic Kidney effectively?

Firstly, illness condition caused by renal inherent cells injury should be controlled firstly.

Secondly, taking proper treatment to reduce cyst fluid can relieve further pressure on renal inherent cells. Then function of inherent cells can be recovered gradually.


Thirdly, repair injured inherent cells, supply requested substances for cell recover and activate the kidney self-repair function.

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