2012年5月31日星期四

The clinical manifestations of polycystic kidney disease

Polycystic kidney disease is a hereditary disease, and oppression kidney cyst will continue to increase renal blood and oxygen supply decreased, the kidney ischemia and hypoxia, renal function will be impaired, resulting in elevated serum creatinine, which caused by the occurrence of renal failure and uremia. Therefore, renal cysts must be treated in time, then the renal cysts in clinical performance?
Pain: for most of the first symptom of polycystic kidney disease, was sustained or paroxysmal ranging from fatigue after the increase. Back or flank pain is the most common symptoms of polycystic kidney disease patients. Age and cyst increases the symptoms became clear that women are more common. Acute pain or pain flare often prompted the cysts rupture, stones or blood clots caused by urinary tract obstruction and co-infection. Chronic pain, enlarged kidneys or cysts stretch renal capsule, renal pedicle, the oppression caused by adjacent organs. The huge hepatic cysts can cause under the right rib pain.
Hematuria: is also the first symptom 
for polycystic kidney disease, the emergence of about half of intermittent painless gross hematuria. More than 90% of patients with intracystic bleeding or gross hematuria. Spontaneous, may also occur after strenuous exercise or trauma. The cause of the hematuria cyst rupture of blood vessels, stones, infections or cancer. General hematuria are self-limiting, 2 ~ 7 days to go away. If bleeding continues more than one week, or patients older than 50 years old, need to be excluded may be cancerous. 
Renal impairment: early renal damage often appears as kidney function decreased concentration. The majority of patients maintain normal renal cyst growth 40 to 60 years; kidney function began to decline, the rate of decline of glomerular filtration rate per year is about 4.4 ~ 5.5ml/min, the development of impaired renal function to ESRD time is about 10 years.
Hypertension: One of the most common early manifestation for the patients with Polycystic Kidney Disease. Young ADPKD patients with normal renal function, 50% of blood pressure greater than 140/90mmHg, while almost 100% in ESRD patients with hypertension. High and low blood pressure and kidney size, cyst how much a positive correlation between age increases continue to rise.
These clinical manifestations of polycystic kidney disease. The main manifestations of the polycystic kidney disease renal enlargement, increased pressure in the envelope, pulling the blood vessels and nerves in the renal pedicle gradually worsening pain. This series of symptoms of polycystic kidney disease patients in a timely manner to improve, it is likely to cause disease progression, life-threatening. With surgical excision of the cyst, reducing the oppression of the kidney, symptoms of transient disappeared, a temporary drop in blood pressure, but the cyst growth environment persists, renal intrinsic cells or damaged state, the sac of fluid in the continuous secretion of large cyst removal of free growth space for the growth of small cysts, the method of surgical treatment of congenital polycystic kidney disease is only a temporary stalling tactics over time, small cysts or will again grow up.
So it is best therapy of micro-Chinese medicine Osmotherapy, Chinese medicine active substances in the form of skin penetration through the kidney area, targeted positioning to make it act directly on the lesion site, expansion of the wall of blood vessels, accelerate local blood circulation, quickly take away the cyst fluid . The same time, the application of Chinese medicine active ingredients inactivate the cyst epithelial cells, reducing generate more cystic fluid and intracapsular pressure drop. Cyst inside and outside the formation of the pressure difference between the cyst continuous retraction, so effective in preventing cyst increases radically reduce the cyst on the surrounding renal tissue of oppression, injury, to achieve the purpose of truly effective treatment in vivo environment. 

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