Polycystic Kidney Disease (PKD), which is a diagnosis result based on
traditional diagnosis methods, is a traditional parlance and the parlance is
right. We get the traditional diagnosis methods from histological perspective
and get the diagnosis result from nephritic structure. But according to western
frontier theory of international kidney disease treatment, pathogenesis of
kidney disease has developed from histological theory to cytological theory. So
the diagnosis of kidney disease has also been refined from clinic to pathology.
Therefore, the scientific diagnosis method of kidney disease is the analysis on
cell function’s damage condition which is based on cells’damage. That is, in
the perspective of cytology, you have the disease of genetic tubular epithelial
variation hyperplasia.
Reasons for having Polycystic Kidney Disease: autosomal dominant inheritance makes tubular
epithelial phenotype transform into cyst epithelial cell; persistent secretion
of Sac liquid makes cyst grow larger; normal structures of kidney are replaced
by cyst. The gradual decreases of glomerulus barrier function, tubular
concentration, reabsorption and regulating functions occur. So, protein, occult
blood happens in routine urine. But tubular epithelial cell disease is the real
disease.
