Polycystic Kidney Disease is mainly caused by hereditary factor which is
inherited from either of parent’s gene. Besides hereditary factor, there are
still other factors that can cause Polycystic Kidney Disease.
Firstly, we should know that what congenital Polycystic Kidney Disease is.
Some people think that Polycystic Kidney Disease is mainly caused by existed
renal tubular diverticulum. Cyst fluid chemical composition of Adult congenital
Polycystic Kidney Disease is similar with plasma ultrafiltrate. It was tested
that there are 20 secretion circles of cyst fluid. Inner diameter of cyst is 0.5
to 1cm normally, or even 3 to 4 cm.
The most acceptable cause of Polycystic Kidney Disease is renal ischemia.
Typically, cyst wall of Polycystic Kidney is very thin in transparent form.
After infected for many times, Cyst wall will become thick, fibrosis or even
calcification. With cysts of PKD patients growing, they can compress renal
parenchyma. However, it is not so severe to damage renal function.
Specialist on Kidney Disease points that congenital Polycystic Kidney Disease
belongs to tumor actually. The older patients are, the higher incidence is.
Pathogenesis of PKD is not researched clearly yet. Maybe it is related with
congenital glomerular and renal tubular structural abnormality as well as
acquired trauma infection.
Knowing about some common knowledge is helpful for patients to prevent this
disease happening. Person who has a familial history of PKD should avoid
infection and cold in order to reduce incidence of Polycystic Kidney
Disease.
