2015年12月19日星期六

PKD (Polycystic Kidney Disease) Treatments in Western Countries

PKD (Polycystic Kidney Disease) is a chronic disorder that the numerous fluid-filled cysts will hamper the kidney function. Up to now, no complete cure is available all over the world. In western methods, the main way of dealing with PKD is by medicines, surgeries, dialysis and kidney transplant. I will introduce them separately.

Western medicines

Western medicines can treat PKD symptomatically. If the cysts rupture, antibiotics are usually prescribed by your doctors. For those who are experiencing pain due to the enlarged kidneys, pain killers might be your only choice to ease the pain. However, PKD patient should try the best to avoid the pain killers because it can cause great stress to the weaker kidney more. Blood pressure medication can be adopted to regulate your hypertension. Urinary tract infection should be treated in the first place to prevent the infection from spreading to the cyst.

Surgeries

The laparoscopic cyst unroofing is commonly used to deal with Polycystic Kidney Disease. Indeed surgeries can remove the bigger cysts and relieve the symptoms very quickly. However, because of the gene problems, the cysts will grow up in a short time. Worse than that, each surgery will cause harm on the weakened kidneys. That is why most PKD patients are not recommended to perform surgeries.

Dialysis

When kidneys fail, most patients will have to undergo dialysis (which can be both hemo- and peritoneal). The condition when patients need to have dialysis varies. Every patient is different, and while some patients need dialysis intervention at say, 5mg/dL (creatinine level), some can hold off until 9mg/dL. The other factors can depend on your age, race, and gender. However, dialysis is not a treatment for PKD, and it can not repair the kidney damage.

Kidney Transplant


When PKD patients’ GFR is lower than 10, most of them will be recommended to be on the waiting list for a kidney transplant. You may be listed on various hospitals but still hard to find a donor. Infection and bleeding are the most common complications of kidney transplant. It is very difficult to deal with the rejection problems. Ten years survival rate is very low for a transplanted kidney. Some studies show suggest that the longer a patient is on dialysis before the transplant, the less time the kidney will last.

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