2015年8月28日星期五

Environmental factors for Polycystic Kidney Disease

Polycystic Kidney Disease is a congenital kidney disease which features with numerous cysts on kidneys. Not every child of PKD parents will get the disease. This is because the occurrence of PKD on the condition of genetic factors and environmental factors. Here are the environmental factors for polycystic kidney disease for your information.

A current theory about the cause of PKD is known as “second strikes theory” which says that one every people with PKD genes will get the disease unless all they get the “second strikes” in their life. In fact, “second strikes” means the environmental factors which stimulate the PKD genes to develop.

Cold. Cold or flu is the common environmental factors to activate the underlying PKD genes to wake up. Meantime, for patients whose renal cysts have already grown up, cold will accelerate the progression of the disease.

Infections. Infections will lead to an imbalanced internal environment, which will benefit the growth of kidney cysts. Repeated infections, such as urinary tract infection, upper respiratory tract infection etc, can activate internal factors of cyst and promoting the formation and cysts growth.

Pregnancy. Pregnancy is surely a burden for kidneys. Usually for patients with PKD, pregnancy not only can drop the kidney functions greatly, but also can affect the fetus. In serious condition, miscarriage may attack the mother-to-be.
Bad emotion. According to a study, bad emotion will disturb the balance of nerve system and endocrine, which will transform the internal environment to secrete cyst fluids to enlarge the renal cysts.

Toxins. Toxins contribute to genic mutation and inborn dysontogenesis, which is known as the common “second strike” to PKD. Some medicines contain toxins which is favorable for the attack of the disease, such as aspirin, NSAIDs, phenacetin, lithium, chaparral tea, starfruit, caffeine, coffee, tea and more foods.

Diet. Unhealthy diet does harm to people with PKD genes. For instance, excessive hunger can lead to inanition while overeating can damage the digestion and absorption functions of stomach with obstacles of blood circulation. Besides, many foods are stimulating factors for patients with PKD, such as coffee, curry food, hamburger, pizza crust and cola etc. Long-term intake of such foods will surely get you involved into PKD sooner or later.


All above is about the environment factors for polycystic kidney disease. If you need any help, you are expected to leave a message below. We are glad to help you.

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