Overview
As a kind of hereditary disease, PKD is caused by dominant inheritance of
autosome, developing progressively, which mostly outbreaks in middle age and
sometimes it is accompanied by liver cyst and calculus, typically characterized
by Renal tubular epithelial cells abnormal growths. After renal tubular
epithelial cell phenotype transform into epithelial cells of cyst wall, it has
secreting function, thus sac liquid increasing. However, without normal
excretion pathway, as the age grows, sac liquid gathers in quantity, thus cyst
enlarging in size and the stress in cyst improving, as well as the surface
tension increasing, finally backache appearing in some allergic patients. When
local cyst is infected, ache appears. Due to the continuous increase of cyst,
normal renal structure is replaced by cyst, thus glomerulus’ barrier function
decreasing, as well as kidney tubules’ concentration, reabsorption and
regulation function. In clinic, it presents Hypertension and checked exception
of URT or renal function.
In addition, if cysts<3cm, it hurts kidney slightly. So patients don’t
have to accept treatment, but regular examination is suggested. If cysts>3cm,
it can produce a certain oppression on kidney, which can damage renal function
gradually. At that time, treatments are necessary. Then what are the treatments
on earth? The essay will make a discussion from three parts.
Western treatments:
I. Puncture, which can remove the cyst in a short time, reduce the burden of
kidney, thus easing patient’s sufferance. However, after the remove of the big
cyst, the small ones have more growing space and chance. They can keep growing
and oppress kidney. In this way, the disease can’t be treated fundamentally.
II. LRCD. Due to reducing cyst’s oppression on kidney, it protects the rest
nephron from extruding, thus improving Renal Ischemia and recovering some
nephrons, finally prolonging the development of PKD. The key point for
successful operation is that cysts should be decompressed fundamentally,
otherwise which can induce an rapid growth for the small ones. In addition, if
the disease develops into later stage, such as Uremia, LRCD makes no sense. In
return, operation may aggravate the disease.
III. Renal replacement therapy. Patients in later stage, whose renal function
is mostly or fundamentally lost, responses awfully to drugs. Also, clinical
symptoms aggravates gradually. It is time to accept renal replacement therapy,
namely hemodialysis or peritoneal dialysis. Because cysts decrease celiac
capacity, patients are suggested to accept hemodialysis. If patients can afford
to the cost, kidney transplant surgery can be considered.
Chinese medicine treatment- Treatment from Shijiazhuang Kidney Disease
Hospital
I. Micro-Chinese Medicine Osmotherapy, which restrains the growing tendency
of cysts, the features of which is: 1. decreasing the secretion of sac liquid,
which means to inactivate cyst epithelial cells, thus restraining the secretion
of sac liquid, finally stopping cysts growing. 2. Increasing the secretion of
sac liquid, which can improve the permeability of cysts’ surface blood
circulation, speeds up the excretion of sac liquid and makes cysts
shrinking.
II. Immunotherapy transplant is the newest treatment on PKD, then how about
its therapeutic effect? It can ease blood anoxic state of kidney intrinsic
cells, inactivate cyst cells, restrain the secretion of sac liquid, increase the
circulation of cyst surface, thus dissolving and reabsorbing the sac liquid
which has been secreted. In this way, it can repair the broken renal tissues,
thus reducing renal burden and normalizing renal vessels, as well as the whole
blood circulation.
Besides regular treatment, daily nursing care is also very important.
I. Home Health Aide: PKD, as a kind of chronic progressive disease, usually
aggravates, which is induced by affective disorder, over fatigue, irregular diet
or Trauma. Thereby, patients with PKD should keep nice mood, alternate work with
rest and build confidence to defeat the disease, so as to cooperate with the
treatment.
II. In diet, patients should take more high-quality protein food: replenish
timely high-fiber, high-vitamin or low-fat food; take proper sugar diet; without
dietary bias, take more corn grains, fresh vegetables and fruits.
In a word, as long as PKD patients accept treatment timely, keep nice mood
and insist proper diet, they can be treated effectively.
