Serum Creatinine is an important index in reflecting renal function.
Creatinine is the metabolic product of creatine in muscle. Every 20 grams muscle
can produce 1 gram creatinine. In normal condition, creatinine can be released
into blood and then will be discharged out of body by kidney. Therefore, the
creatinine level can keep its normal range within 0.6 to 1.2mg/dL
(50-110mmol/L), but some reference value may vary with different hospitals.
However, for PKD patients, if they do not receive effective prevention and
treatment, their cyst will enlarge kidney tissues persistently. As a result, the
enlarged cysts will oppress the kidney tissues thus causing renal ischemia and
anoxia. As kidneys can not get sufficient oxgen and blood supplement, it can
initiate fibrosis of kidney thus causing glomerulosclerosis. As a result, the
kidneys will lose it normal filtration function so the creatinine will
accumulate in body. Therefore, the patients’ creatinine level will increase.
In fact, creatinine level is not a very sensitive index in assessing renal
function. In most cases, the PKD patients’ creatinine level does not increase
until they lose more than half of their renal function. Therefore, the patients
should quit their wrong opinion that if their creatinine level does not
increase, their kidneys do not have damage at all. Once patients notice their
creatinine level increase, they should not delay their treatment any longer.
In order to decrease creatinine level, the PKD patients should receive proper
treatment to prevent the enlargement of cysts. Then on this base, they can
further repair the damaged renal function so as to recover their normal kidney
filtration function. If so, their kidneys will be able to dischrge the toxins
and wastes in body normally so the creatinine level will recover the normal
level.
In a word, if patients can get a proper treatment, they will certainly be
able to decrease their creatinine level. If you are confused about how to
decrease your high creatinine, please consult us on line or email to
kidney-treatment@hotmail.com.
