The cysts of PKD (Polycystic Kidney Disease) patients will surely cause 
damage to the kidneys, leading to a lot of symptoms. Those symptoms will in turn 
aggravate the kidney damage.
1. High blood pressure
Usually, high blood pressure is the primary symptom of PKD patients. High 
blood pressure secondary to PKD will surely aggravate the kidney damage. 
Patients with PKD and High Blood Pressure have a higher risk of developing 
cardiovascular diseases.
2. Proteinuria ( protein in urine)
For patients with PKD, the incidence of proteinuria reaches up to eight 
percent. Proteinurina is caused by the continuous growth of cysts causing damage 
to the glomerular membrane, which loses its normal function of filtering wastes, 
proteins and other substances.
3. Hematuria (blood in urine)
As for PKD patients, hematuria can be caused by the following two reasons. 
One is the rupture of the cysts and the other is the damage of glomerular 
filtration membrane.
4. Enlarged kidneys
With increase of cysts in both number and size, kidneys will enlarge and lead 
to unbalanced development of two kidneys. Additionally, kidney functions will 
decrease day by day with the enlargement of kidneys.
5. Abdominal lumps
More than half patients will feel lumps on both sides of abdomen when kidney 
enlarges to a certain level.
6. Anemia
Anemia of PKD patients can be caused by the loss of blood in urine and the 
lack of EPO secreted by kidneys.
7. Back pain
It is usually the first symptom that impels patients with PKD receive 
treatment.
Progression of PKD might be gradual and symptoms may not present until the 
late stage of Kidney Failure. Hope patients receive treatment as soon as 
possible once PKD is diagnosed.
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