2015年9月22日星期二

What Does Creatinine Level 125 and No Symptoms Mean to PKD patients

Q: I have PKD (Polycystic Kidney Disease), but no symptoms yet. I am 63 and last time I checked serum creatinine 125. Is it possible I will not be affected?

A: Your creatinine level is 125. It is still in normal range, but at the highest limit. Generally patients with PKD will have high blood pressure in 30s, high creatinine level in 40s, and kidney failure in 50s. You are 65, but your general condition is still good, so you are already the lucky one compared to others.

Kidneys have strong ability of functional compensation. Even you have no symptoms, your kidney function may have been damaged. Many patients found kidney disease when they begin to have nausea and continuous vomiting. It is too late. When they have obvious symptoms, it is already at Renal Failure stage. Therefore, I suggest you receive treatment early.

Apart from creatinine level, I suggest you to take other tests, especially cystsain test and Glomerular Filtrate Rate (GFR) test for the two indexes are more exact in reflecting the kidney function.

Cystsain is in blood test. It is more sensitive than creatinine. If kidney function is damaged, it will increase earlier than creatinine. Even when creatinine is still normal, the Cystsain in blood will be high. So it can help detect kidney damage early.

GFR is short of Glomerular Filtration Rate, which reflects the function of glomeruli. The normal range for healthy people is 100-120. For people over age 60, if GFR is over 60ml/min, it is considered ok.


All symptoms and complications mostly result from underlying renal cysts for PKD patients. Renal cysts keep enlarging, which causes declines to renal functions. If the tests show your renal functions decreases, you need to take measures to control and remove renal cysts as soon as possible. Meantime, tonic herbs for kidneys are necessary for improve your renal functions. If you still have confusion or problem, you can mail to kidney-treatment@hotmail.com

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