Autosomal Dominant (Adult) PKD is one of the commonest genetic diseases. In
America, there are five hundred thousand sufferers with this disorder. 50
percent of them will be in Renal Failure by the age of 60. 10 percent of all
people undergoing dialysis are doing so due to this disease. Here, we mainly
talk about an gastrointestinal complication of Adult PKD, diverticulosis.
Diverticulosis
Diverticula are small herniations or pouches (sacs) that may develop in the
wall of the large intestines. When these herniations are filled with feces, the
feces can get trapped there and become not be eliminated with the rest of the
bowel movement.
Diverticulosis is used to describe the condition that there are many
diverticula. This occurs more often in people with PKD who are on dialysis or
have had a kidney transplant than any other renal disease. Also, these persons
tend to have more complications from this condition like infection called
diverticulitis.
Apart from the digestive system, Adult PKD may cause other systemic problems
through affecting the excretory system and cardiovascular system.
Excretory system
Healthy kidneys are responsible for filtering the blood, reabsorbing 98
percent of the filtrate and regulating the blood composition. In addition, the
kidneys can produce important hormones like erythropoietin, renin, and
calcitriol. Renin is a vital hormone which can regulate the blood pressure.
Cardiovascular system
Adult PKD can also affect the cardiovascular system, as it puts the person at
risk for high blood pressure, intracranial aneurysms, and MVP. With persistent
and long-term high blood pressure, heart damage can be caused. About 50 percent
of patients with PKD die from the heart and vascular complications of PKD, not
Kidney Failure.
As one of the largest kidney disease hospital all over the world, we have
more than 20 years' experience and expertise in PKD treatment. If you or your
beloved one is diagnosed with Adult PKD, we're here to help. Call +86 311
8926-1580 or consult our online service if you have any questions about the
disease.
