2015年5月26日星期二

What Causes Nausea in Polycystic Kidney Disease

Typically, people with Polycystic Kidney Disease present symptoms in early or middle adulthood. Common symptoms include discomfort of pain in the abdomen or side, hematuria (blood in urine), frequent urination, and intense crampy pain from kidney stones. In some cases, patients may have nausea, fatigue, etc due to slowly developing kidney failure. What are the causes?

Kidneys are vital organs that filter toxins out of the blood, help maintain calcium and water balance, and produce hormone that stimulates red blood cell production in the bone marrow. Substances filtered our by the kidneys, along with any excess water, are expelled during urination.

For people with Polycystic Kidney Disease, there are clusters of fluid-filled sacs, called cysts, developing in the kidneys and interfering with their ability to filter waste products, such as creatinine, urea nitrogen, from the blood. The growth of cysts causes the kidneys to become enlarged and eventually lead to Kidney Failure.

With long-term kidney disease, the patients begin to feel tired and ill. Appetite decreases, because toxins begin to build up in the blood stream, causing nausea and weight loss. Elevated blood urea nitrogen occurs, and the urea in intestinal tract will be decomposed into ammonia with the help of bacterium. The ammonia will irritate the mucosa of intestinal tract, resulting in nausea. Generally, the high the BUN is, the more severe the nausea will present.

In addition, the urine concentration ability will reduce in case of Kidney Failure. Consequently, patients may have increased urine at night. With much loss of moisture at night, the blood will become concentrated. The BUN will rise and their nausea will aggravate in the morning.


If you feel nauseous, it is important to rest and not undergo any activity that might worsen the feeling. Meanwhile, find an effective treatment to get rid of nausea in Polycystic Kidney Disease. Any help? Consult our online experts.

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