2015年5月14日星期四

Why does A Person with PKD Suffer from Nausea and Vomiting

PKD is an inherited disease, which is passed on from parents to children through genes. 90% of people with this disease have ADPKD, or adult PKD. Initially, there are usually no symptoms. As the disease progresses, patients will experience some discomforts. Here, we would talk about the cause of nausea and vomiting in PKD.

Renal Failure

PKD is caused by an inherited gene defect. The genetic defect results in widespread formation of cysts in the kidneys. Over time, enlarged cysts will increasing age is accompanied by a reduction of blood flow and scarring within the kidneys. Kidney Failure can occur eventually.

If this happens, the kidneys are not able to eliminate waste products from the blood, so many different waste products will accumulate in the blood, leading to Uremia. Symptom of waste accumulation include nausea and vomiting, itching, confusion, decreased appetite, etc.

Brain aneurysm

Approximately 5%~10% of patients with the disease have risk of developing an brain aneurysm-bulging in the blood vessel wall. Some aneurysms may leak or rupture, resulting in symptoms such as nausea and vomiting, headache, and pain when moving the neck. Immediate medical treatment is needed to treat these symptoms.

Kidney stones

About 20%~30% of people with PKD develop this condition. With the urine tending to be more acidic that normal, the stones which favor an acidic environment will form. Apart from nausea and vomiting, kidney stones can also lead to symptoms including back, side, or abdominal pain, bloody or cloudy urine with foul smelling, increased urination, fever, etc.


Corresponding treatment for nausea and vomiting in PKD should be adopted based on specific cause. With the advances of modern medical technology and techniques, new treatment has been developed in China which can eliminate the symptoms and prevent further progression of the disease. If you or your beloved one is diagnosed with PKD, we are here to help.

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