2015年5月29日星期五

What are the Causes of Swelling with Polycystic Kidney Disease

One of the most common problems associated with Polycystic Kidney Disease is edema, which is when fluid builds up in the body and leads to swelling. This may cause discomfort, and it can also be an early sign of PKD. Therefore, it is important to know how it relates to the disease.

Features

Swelling occurs when the small blood vessels in the body leaking fluid, and then the kidneys will retain water and sodium. If this happens, small blood vessels get a message from the brain that there is excessive fluid within the body, which leads to the blood vessels to release even more. Soon after this cycle starts, the fluid will become trapped in the body tissue, resulting in swelling. Patient often have edema in the ankles, hands, feet, legs, etc.

Polycystic Kidney Disease and swelling

The most common cause of swelling in the case of PKD is an impairment of kidney function or much loss of protein in the urine.

Impairment of kidney function can be caused due to oppression on renal tissues of gradual enlargement of renal cysts. Consequently, the Glomerular Filtration Rate (GFR) will decline over time. However, in some cases, the reabsorption function of renal tubule still remain normal, so water and sodium retention occurs, thus resulting in swelling.

When the swelling is caused by protein levels in the urine, it is caused due to damage of barrier function on glomerular basement membrane. In this case, much protein in the blood will be spilt out, resulting in decline of blood plasma oncotic pressure. Water will be permeated into tissues spaces, causing swelling.


If you want to get rid of swelling, we should find a thorough treatment for PKD. In our hospital, we apply a natural remedy to shrink the renal cysts, prevent the reduced kidney function, and restore the damaged kidneys. If you need any help, contact us online.

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