Polycystic Kidney Disease is known as the typical genetic kidney disorder. No
wander, the best treatment for the disease is gene therapy. However, as the gene
therapy of Polycystic Kidney Disease is not available, the alternative treatment
for gene therapy is put into agenda.
Why gene therapy can not be put into application for Polycystic Kidney
Disease?
The reason why the gene therapy is still not available after more than 50
years research is that:
● ADPKD is a kind of focal segmental lesions, and cysts only occur to 1-5% of
renal tubules which have the dysfunction of renal tubule epithelium, so it is
hard to transfer the carrier into the focal segmental lesions.
● The DNA fragment of the disease causing the gene is large and by far, there
is no method for the carrier selection and gene transfer.
Is there any alternative treatment to gene therapy of Polycystic Kidney
Disease?
We have to face the fact that there is no gene therapy which can cure PKD by
far. However, we can not let the PKD progress as it should. We should find
alternative treatment to gene therapy to prevent the development of PKD and
avoid renal failure.
As the root cause for PKD is the constant enlargement of renal cysts, the
point of alternative treatment should be focused on the control of renal cysts.
As long as the renal cysts don’t grow up any more, it won’t lead to further
kidney damages. In addition, the next step is to repair the damaged kidney
tissues. When kidneys can work better to filter out the toxins and the renal
cysts are small enough not to harm kidneys, surely patients will live a normal
life. If any treatment can achieve these goals, we say it the alternative
treatment of gene therapy.
For this kind of treatment, Micro-Chinese Medicine Osmotherapy is designed.
Micro-Chinese Medicine Osmotherapy is a new form of Traditional Chinese
Medicine, which uses herbs to affect epithelial lining cells externally.
Lining cells locate inside the cysts membrane which generates the cyst fluids
constantly and enlarge renal cysts. When Micro-Chinese Medicine Osmotherapy is
conducted, it can change the structure of the lining cell so as to shrink renal
cysts to small size. In addition, other herbs in this treatment can help the
damaged kidney cells to self-cure, elevating kidney function levels.
Mostly, patients with Polycystic Kidney Disease can see the shrinkage of
renal cysts within 2 weeks through screening and feel the improvement of kidney
functions through the test of GFR.
