PKD is a kind of autosomal dormant genetic kidney disease with grape-like
appearance kidney and the countless magnitude-varied cysts in cortex and medulla
of the kidney when cut open. Most patients of this kind have the characteristic
of abdominal apophysis with the complications of blood urine, high pressure,
lumbago, kidney stone and polycystic liver and etc. The severe one can show the
symptoms of the high-level of creatine and the insufficiency of renal
function.
Operation Treatment:
Operation treatment has always been adopted in the past by People with PKD,
the aim of which is to remove the large cysts and made them recession. But the
removal of the large cysts provides the room and space for the growth of small
cysts. With the acceleration of that growth, the kidneys are oppressed once
again. So this therapeutic method for PKD not only cannot make the illness
better thoroughly, but also leave the new trauma both physically and mentally.
Worse still, after the operation for nearly about 6 months, the previous
symptoms would be backing to recurrence and be gradually more aggravating
compared to the past. Also, the renal function would be taking a sudden turn and
becoming worse rapidly.
Dialysis and Transplant: When it is coming into the end stage of renal
failure, dialysis treatment should be adopted immediately. The survival rate
of the kidney transplant for PKD is similar to other operations, but the
accompanied disease would increase the difficulties of postoperative therapy and
influence the result of transplant.
Treatment for Hematuresis: When there is blood in urine, besides the
necessary treatment according to the definite reasons, the patients should
reduce their activity or stay in bed. For the patients of dialysis or are to be
dialyzed, TRAE could be considered if the Hematuresis occurs repeatedly and
uncontrollably.
Treatment for Infection: The main complications for this kind are renal
parenchymal and inside-cyst infection. The general principal for the treatment
is the combined application of antibiotics.
Treatment for Combined Upper Urinary Tract Calculus: Based on the position
and size of the calculus, the treatment could be conducted according to the
management principle of lithangiuria.
Treatment for Hypertension: Renal ischemia and the activation of the system
of RAA (aldosterone) are the primary causes for the occurrence of hypertension,
so the drugs for depressurization could be selected according to this.
The Western Medicine possesses a wait-and-see attitude toward the patients of
PKD, so the therapeutic method for the PKD would be thrown into a passive
position, that is: surgical operation would be undergone not until the small
cysts have enlarged; hemodialysis would not be conducted until the renal
function is insufficient. As far as concerning the effect of those methods, many
patients of PKD have lost their confidence in treatment. The specialists
conclude that for the treatment of PKD, it is not supposed to be the pure
symptomatic treatment, but to be starting from the nosogenesis so as to block up
fundamentally the fibrosis of kidney.
