Serum creatinine is the metabolism product of our muscles. In our muscles,
creatine can form into creatinine through various steps and then the creatinine
will be released into the blood and be discharged out of our body with urine.
That is to say, serum creatinine and the total number of muscles are closely
related. The serum creatinine levels can not easily affected by food and urine
volume. Clinically, the detection of serum creatinine is a main index of valuing
kidney function.
The normal value of serum creatinine
The normal value of serum creatinine can be different in different countries
and even different hospitals in the same country. Generally speaking, the normal
value of serum creatinine is 44-133umol/L. When the value of serum creatinine
surpasses 133umol/L, it means your kidney has been damaged in most cases.
The normal values of serum creatinine
Male: 54-106umol/L (0.6-1.2mg/dL)
Female: 44-97mol/L (0.5-1.1mg/dL)
Children: 24.9-69.7umol/L
Factor that influences high levels of serum creatinine
When the glomerular filtrations decline about 2/3 of normal people, serum
creatinine levels begin to arise sharply. That is to say, patients can not feel
obvious discomforts when the kidneys are slightly damaged because of kidneys’
great compensation. That is why many people do not experience vomiting, nausea
and faint until the kidneys are greatly damaged.
Factor that influences low levels of serum creatinine
Diets that are low in protein can cause low creatinine levels. Foods that are
high in creatinine phosphate include salmon, pork, tuna and beef, all of which
are high in protein.
Pregnancy may cause low creatinine levels in the blood. Once the fetus starts
developing in the womb, nutrients are transported from the mother to the baby
via the umbilical cord. Pregnant women may have less creatinine phosphate to
break down due to the changes in the body.
Decreased muscle mass can lead to low levels of creatinine. Aging causes a
natural decline in the amount of muscle mass in the body. Muscular dystrophy and
myasthenia gravis are examples of diseases that can cause decreased muscle mass.
Disabilities that limit movement can also cause reduced muscle mass due to lack
of muscle use.
Liver disease can also contribute to a decline in serum creatinine
levels.
