2016年3月23日星期三

Side Effects of Dialysis for PKD patients

Polycystic Kidney Disease (PKD) is serious kidney disease. If patients do not receive treatment in time, more than 50% of them will develop into Renal Failure. As a result, many patients have to depend on dialysis to maintain their lives. However, dialysis has too many side effects on PKD patients.

Dialysis is also named as artificial kidney just like a filter. It can only remove the metabolic wastes and toxins in body, but can not improve their renal function at all. Moreover, once patients begin to undergo dialysis, they will not be able to get rid of it. With the aggravation of their disease, they have to increase their times of dialysis.

In addition, dialysis also can cause a series of complications.

1. Usually, PKD patients on dialysis have two kinds of Hypertension. One is caused by hypervolemia. Dialysis can discharge much water out of body so their blood volume will decline, As a result, the patients will have Hypertension. This kind of Hypertension covers about 70~80% of patients with Hypertension on Dialysis. Another kind is renin Hypertension. As renal blood volume declines, the secretion of renin increases, which can cause angiotensin to increase. Therefore, patients will have Hypertension.

2. If patients have dialysis over time, they will lose much sugar, amino acid, soluble vitamin and other nutrition. In addition, many patients also have poor appetite, nausea. So they are very likely to have calorie malnutrition and vitamin insufficiency. It increases the chance of infection. In addition, patients on dialysis also have vascular access and external blood circulation, which also increase the chance of infection. Patients on dialysis often have infection in their respiratory tract, digestive tract and urinary tract. If patients have infection in their vascular access, it is very likely to cause septicemia. Among patients on dialysis, the incidence of Hepatitis virus is very high.


As dialysis have so many side effects on patients. Therefore, it is very important for all PKD patients to receive treatment in early time so as to prevent the disease development in advance.

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