What is the sophisticated relationship between Hypertension and Polycystic Kidney Disease? Everybody knows that Hypertension is easy to cause
cerebrovascular disease and cardiovascular disease. Actually, Hypertension is
also closely related with Kidney Disease. Well then, what is the relationship
between Hypertension and Polycystic Kidney Disease (PKD)?
Medical research has shown that Hypertension usually causes renal injury, and
contrarily, renal injury can also cause Hypertension. Both of them affect each
other, resulting in vicious circulation easily. Most patients pay less attention
on treating Polycystic Kidney Disease (PKD) after they were told that this
disease is a kind of genetic disease. Usually for this reason, this disease
always develops into the most serious stage of Kidney Disease, Uremia stage,
unconsciously.
Polycystic Kidney Disease has a progressive development and usually occurs
among adult people, with abnormal proliferation of renal tubular epithelial
cells as its dominant characteristic. When renal tubular epithelial cells turn
into cystic epithelial cells, they begin to have secreting ability and keep
secreting fluid more and more, but there is no normal way to excrete increasing
fluid. For this reason, cysts grow bigger and bigger with time passing. When
cysts grow to some certain degree, they will replace healthy renal tissue. Then
renal function declines gradually. At this moment, Hypertension and routine
urine test abnormality appear in clinical observation.
The medicine that Polycystic Kidney Disease (PKD) patients take may even
cause damage to injured kidney due to nephrotoxicity. Besides, most patients who
suffer from Hypertension usually go to hospital for cardiovascular tests
directly instead of kidney routine tests. Therefore, kidney injury can not be
found in time, which is one of main causes of Uremia.
If blood pressure can not be controlled effective, it can damage kidney.
Meanwhile, Hypertension may develop into Hypertensive Nephropathy. Kidney is an
internal organ consisting of countless micro blood vessels, and kidney internal
mini arteries may be hardened if Hypertension can not be controlled in a long
term. This is also the reason why most Hypertension patients have kidney injury.
If such injury can not be treated in time, it will cause glomerular sclerosis,
renal interstitial fibrosis, or even Renal Insufficiency and Uremia finally.
Contrarily, Polycystic Kidney Disease (PKD) can also cause Hypertension. The
more serious kidney injury is, the high blood pressure is. In late stage of
Renal Failure, 80% patients get obvious Hypertension.
