Many factors affect prognosis and life expectancy of nephrotic syndrome, including infections, hyperlipidemia, hypertension, age, acute renal failure etc.
To achieve a better prognosis and prolong life expectancy, timely and appropriate treatment should be received. The goals of these treatments are removing underlying causes and factors inducing, relieving edema and proteinuria, lower high blood pressure, increased plasma albumin, decreased hyperlipidemia, protection of kidney function and reducing recurrence rate.
Nephrotic syndrome is renal damage caused by immune complex deposition and kidney inflammatory reactions, therefore, anti inflammation is very important for relieving proteinuria, swelling and other clinical symptoms.
Corticosteroids are widely used drugs to treat nephrotic syndrome. These drugs have strong and nonspecific anti-inflammatory effects and may also regulate the biosynthesis and metabolism of sugar, fat and protein.
From patients with nephrotic syndrome often have swelling due to massive proteinuria and low plasma protein, diuretic therapy is very neces But during diuretics intake can cause insufficient volume of blood, thrombosis and electrolyte imbalances. If any discomfort or side effects after taking diuretics, tell your doctor and adjust the quantity or change other diuretics.
Long-term intake of corticosteroids and diuretics can cause many side effects, such as osteoporosis, hypertension, hairiness, inhibition of growth that are especially favorable for children and adolescents.
One measure is to add Chinese medicines corticosteroids and diuretics. Some Chinese medicines have the function of inhibiting immunoreactions, but single use of Chinese medicines is not well suited to the conditions of severe illness and usually takes relatively long time to take effect. Therefore, the combination of Chinese and Western medicine can achieve better curative effects to the exclusive use of the hormone or Chinese medicines. Chinese medicines can relieve side effects and injuries to the body and some Chinese medicines as Astragalus membranaceus can increase albumin synthesis in the liver and relieve proteinuria, hypoalbuminemia and edema.
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