2016年3月24日星期四

Be Alert of the Five Complications of Autosomanl Dominant Ploycystic Kidney Disease (ADPKD)

According to the newest survey, at least 10% of dialysis patients (End-stage Renal Failure patients) are caused by Autosomal Dominant Ploycystic Kidney Disease (ADPKD). In Shijiazhuang Kidney Disease Hospital, from the year 2008 to April 2011, Professor Lv has made a survey: we have received 1052 cases of Autosomal Dominant Ploycystic Kidney Disease (ADPKD) patients, which exceeds much more than some other big hospitals in Shanghai, Beijing of China. Based on so many clinical observations and treatments, we hereby try to give more information about the five common clinical complications of Autosomal Dominant Polycystic Kidney Disease(ADPKD) and hope it will arouse your attention as well.

Patients with Polycystic Kidney Disease have multiple cysts on both kidneys. Autosomal Dominant Ploycystic Kidney Disease (ADPKD) always runs in family. If one parent carries the genes, the child has a 50% possibility of developing Polycystic Kidney Disease.

There are some common complications of Autosomal Dominant Polycystic Kidney Disease:

1. Hypertension (High blood pressure)

Among the patients we have treated, 66% have high blood pressure. Before Serum increases, the appearence of hypertension (high blood pressure) signifies that the kidney tissues, blood vessels have been pressed by the enlarging cysts, which causes the insufficiency of blood and oxygen of the kidneys. And then affects a series reaction of Renin-Angiotensin-Aldosterone, which can cause the concentration of Angiotensin, and the blood vessels will contract and then blood pressure is elevated. Blood pressure will aggravate the damage of the kidney function, and the declined kidney function may in turn make the blood pressure hard to control.

2. Kidney stones

56% patients are accompanied with Kidney stones. If kidney stones obstruct the ureter, it will cause great pain. To remove the kidney stones, the usually used methods are extracorporeal lithotripsy, Percutaneous nephrolithotomy (PCNL) etc. However, for PKD patients, these methods may lead to trauma of the kidneys because the external intervention may break the cysts and cause damage. So for kidney stones, you'd better choose natural treatment like Micro-Chinese Medicine Osmotherapy.

3. Multiple cysts in other organs, like polycystic liver, polycystic spleen, polycystic pancreas, polycystic Ovary, polycystic lung etc.

4. Hematuria

About half of the patients may present hematuria. With the cysts enlarging with time, the pressure on kidney tissues and blood vessels will increase, endothelial cells are damaged and blood will leak out. It can be gross hematuria or microscopic hematuria.

5. Urinary Tract Infection caused by PKD

Any urinary tract infection should be treated promptly with appropriate antibiotics.

As the multiple cysts will damage the normal kidney structure, and function with their enlargement, so many complications will appear. For the PKD patients, they'd better control the PKD progress in the early stage, so as to avoid the damage of the kidney functions, and influence the other organs and systems.


If you want to know more information, or you need the expert's advice, you are welcome to consult us online for free, or email to kidney-treatment@hotmail.com

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