Polycystic Kidney Disease (PKD) is a genetic disease. At present, in the
western medicine, there is no cure and effective treatment for the disease.
Therefore, as the cysts enlarge persistently, they will oppress the kidney
tissues thus making kidney fail. With the occurrence of Chronic Renal
Failure(CRF), the patients will have a series of complications.
1. Skin disease
As patients’ renal function declines, amount of toxins and wastes will
accumulate in patients’ body thus affecting other organs and skin. The patients
often have skin itch, dry skin and some patients even have brown chromatosis in
their skin. Skin itch makes patients extremely uncomfortable and painful. If
they scratch their skin with their hands frequently, it will make their skin
thicken, keratinize and have lichenification. Skin itch is closely related to
hyperthyroidism.
2. Respiratory disease
Some patients with CFR may have Uremic Pneumonia. There are two main causes
of Uremic Pneumonia. First, uremic toxins cause the permeability of pulmonary
alveoli to increase; second, the retention of water and sodium makes circulatory
volume rise. In addition, about 15~20% of patients with CFR also have Uremic
Pleuritis.
3. Blood systemic diseases
Many patients with CRF often have Renal Anemia. After their disease develops
into End Stage Renal Failure, nearly 100% of patients will have Renal Anemia.
The main causes of Renal Anemia are as follows:
(1) The patients often have vomit, nausea and poor appetite. Therefore, the
patients can not get sufficient raw material of blood.
(2) Uremic toxins inhibit the bone marrow thus declining the production of
red blood cells.
(3) Some patients often have bleeding in such as bleeding in digestive tract
and so on.
(4) The most important cause is that kidney can not secrete enough
hemopoietin thus causing the number of red blood cells to decline.
4. Electrolyte disturbance
As kidney can not discharge the excessive potassium in their body, they are
very likely to have Hyperkalemia (potassium level in serum >5.5 mmol/L. There
are several causes of Hyperkalemia.
(1) Eat too much food with high potassium
(2) Take medicines that contain high potassium
(3) Take medicines that can inhibit the potassium discharge from body
If the patients with PKD can not receive treatment as early as possible, it
will cause a series of complications that can accelerate the disease development
and cause more difficulties for treatment. Therefore, the patients should choose
an effective therapy once they are diagnosed with the disease so as to prevent
their disease from developing into Renal Failure.
