2016年3月19日星期六

Causes and Symptoms of High Creatinine

Patients with kidney diseases are often often confused what have caused their high creatinine. Actually, continuous high creatinine level most probably indicate severe kidney function declination. To know it better, we will talk about causes and symptoms of high creatinine so as to help make an early finding of the illness condition.

What are the causes of high creatinine?

To begin with, we'll first learn about what is creatinine. Creatinine is a metabolic waste in the blood which is mainly filtered by glomeruli and eliminated with urine. The chemical waste is a by-product of normal muscle contractions. Creatinine produced each day remains unchanged because muscle mass stays the same.

Normal creatinine range differs with gender. Compared with men, women usually have lower creatinine levels compared, because women have less muscle tissue. Among adults without kidney disease, men have approximately 0.6 to 1.2 milligrams/deciliters (mg/dL) of creatinine, while women have between 0.5 to 1.1 mg/dL. Besides, those who eat a lot of meat or build muscles through weight training or other exercise may show higher amounts of creatinine.

As serum creatinine is mainly filtrated and excreted by our kidneys, any cause that damages the function of the kidneys will probably raise the creatinine level in the blood. What we should do is to recognize whether the process leading to kidney dysfunction is longstanding or recent.

The most common causes of longstanding kidney disease in adults are high blood pressure and Diabetes Mellitus. High serum creatinine may also be caused by ingestion of large amount of dietary meat. Other reasons may also cause high serum creatinine, which can be seen as follows:

1. Dehydration can lead to elevated creatinine by causing blood fluid concentration and reduction of kidney blood flow.

2. Nephrotoxic medicines taken by those with kidney diseases can lead to elevated creatinine, which can be irreversible.

3. Over fatigue may lead to intermittent high serum creatinine.

For those with continuous high serum creatinine, a timely treatment is necessary because it most probably indicate severe kidney damage.

Symptoms of high creatinine

Symptoms of high levels of creatinine in the blood are the same as kidney failure symptoms. Some people find out they have kidney failure when extreme creatinine amounts show up in routine blood tests, without feeling any symptoms at all. Yet symptoms as follows may be found in some patients: dehydration, weakness, or feeling tired, confusion and shortness of breath.


As high serum creatinine is so closely linked to kidney function and may indicate severe kidney damage, it is necessary for patients to prevent risk factors and take timely treatment, especially for those with continuous high serum creatinine.

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