FSGS (focal segmental glomerulosclerosis) is a disease that affects the
kidney’s filtering system causing scarring and loss of large amounts of protein
in the urine. It is a cause of nephrotic syndrome in children and adolescents,
as well as an important cause of kidney failure in adults. It accounts for a
sixth of nephrotic syndrome.
It is normally only diagnosed after a biopsy test of the kidney. What you see
under the microscope is that the “glomeruli”, which are the tiny structures
which filter the blood to make urine, are scarred.
A person suffering from FSGS may experience edema,
hypoalbuminemia, hyperlipidemia and hypertension. In adults it may also present
as kidney failure and proteinuria.
Is FSGS curable?
The out come is very variable, and you will need to ask your specialist how
thins are likely to be in your case. FSGS may continue for many years, requiring
only regular check-ups with blood tests. In some cases, FSGS may go away. When a
person get fluid retention with ankle swelling, it is an indication of worsen
kidney disease. A lot of people with FSGS may develop end-stage renal failure
and receive dialysis or transplantation.
Besides the symptoms, a lot of complications draw patient’s attention. High
blood pressure may develop. This damages the kidneys and puts strain on the
heart and the rest of the circulation. Therefore, high blood pressure should be
treated vigorously. High cholesterol level may occur, requiring diet change and
sometimes lowering drugs as well.
“Is FSGS Curable?” All in all, there is not a unique answer to this question.
If you are diagnosed with FSGS, we are here to help you!
2016年12月21日星期三
Treatment for FSGS in Children in China
FSGS (focal segmental glomerulosclerosis) is a kidney disorder that affects
the kidney's filtering system causing scarring and loss of large amounts of
protein in the urine. It is a common cause of nephritic syndrome. FSGS can occur
in adults and children. If your child is diagnosed with FSGS, a new treatment
immunotherapy is recommended which is available in China.
Treatment for FSGS in children – immunotherapy
What is immunotherapy?
Immunotherapy is a comprehensive therapy which is created based on the theory of immunology. It is though that 95% kidney disease including FSGS is caused by the disorder of immune system, meaning the disorder of immune system leads to foreign substances attack the body and if it destroys the kidneys, it is more likely to cause kidney disease. The destroyed part of kidney determines the type of kidney disease. Immunotherapy is characterized by treating FSGS step by step from the accurate diagnosis, treatment and follow-up. It aims to restore kidney and treat FSGS by improving and rebuild the immune system.
How to treat FSGS?
Firstly, accurate diagnosis is a very important. A battery of tests will be ordered which can provide enough information to the doctors for the evaluation. Then an experts team will meet and discuss the best treatment plan, according to the individual condition. There are more than one therapies including traditional Chinese medicine, medicated bath, varieties of immunosuppressive drugs with low side effects, Micro-Chinese Medicine. All these therapies target to alleviate the different symptoms and restore the kidneys.
After the immunotherapy, generally symptoms can be alleviated and kidney function can be improved in different degree. More important, immune system is improved so it can help to fight against the diseases.
If you are diagnosed with FSGS, we are here to help you!
Treatment for FSGS in children – immunotherapy
What is immunotherapy?
Immunotherapy is a comprehensive therapy which is created based on the theory of immunology. It is though that 95% kidney disease including FSGS is caused by the disorder of immune system, meaning the disorder of immune system leads to foreign substances attack the body and if it destroys the kidneys, it is more likely to cause kidney disease. The destroyed part of kidney determines the type of kidney disease. Immunotherapy is characterized by treating FSGS step by step from the accurate diagnosis, treatment and follow-up. It aims to restore kidney and treat FSGS by improving and rebuild the immune system.
How to treat FSGS?
Firstly, accurate diagnosis is a very important. A battery of tests will be ordered which can provide enough information to the doctors for the evaluation. Then an experts team will meet and discuss the best treatment plan, according to the individual condition. There are more than one therapies including traditional Chinese medicine, medicated bath, varieties of immunosuppressive drugs with low side effects, Micro-Chinese Medicine. All these therapies target to alleviate the different symptoms and restore the kidneys.
After the immunotherapy, generally symptoms can be alleviated and kidney function can be improved in different degree. More important, immune system is improved so it can help to fight against the diseases.
If you are diagnosed with FSGS, we are here to help you!
2016年10月28日星期五
Stages of Polycystic Kidney Disease
Polycystic Kidney Disease is a kind of hereditary Kidney Disease, with
certain law objective law of occurrence and development. Stages of Polycystic
Kidney Disease development can be listed as follows:
StageⅠ. Occurring Stage. Because this disease is a kind of hereditary disease, cysts have already formed when they were born. And normally, cysts cannot be found easily before patients are 20 years old due to the small size of cysts. If there are Polycystic Kidney Disease patients among family members, other family members should go to hospital for a check so as to observe cysts growing condition as early as possible. During this stage, patients should pay attention to daily life care.
Stage Ⅱ. Growing Stage. Cysts can grow faster when patients are in the range of 30 to 40 year old. This period is called growing stage medically. During this stage, observation on cysts growth should be strengthened. Western Medicine has no effective treatment to cure this disease in this stage, and it only can treat symptoms like Hypertension and other symptoms, which is absolutely passive. Actually, patients still need active treatment in this stage with the purpose of blocking or delaying cysts growing and prolonging patients’ life through the application of Chinese Medicine with stronger ability of activating blood and eliminating blood stasis. In another word, this stage can be the key stage for Chinese Medicine to delay cysts growing by activating blood and eliminating blood stasis.
Stage Ⅲ. Enlargement Stage. When patients are more than 40 years old, cysts can grow and enlarge further. From cysts increasing to more than 4cm to cysts rupture, this period is called Enlargement Stage. With cysts growing and increasing, more and more clinical symptoms like, waist ache, Albuminuria, Haematuria, increased blood pressure, etc, appear. Close observation is needed at this moment. As for treatment, Chinese Medicine can be taken to activate blood, eliminate blood stasis, excrete turbid and remove cystic fluid that can be harmful to renal function, in order to protect renal function.
Stage Ⅳ. Rupture Stage. If cysts keep growing, they may rupture under actions of external factors. Patients should be hospitalized to accept treatment once cysts rupture and control infections actively in order to prevent Septicemia and acute aggravation of renal function, which is helpful to treat other symptoms effectively.
Stage Ⅴ. Uremia Stage. During this stage, patients should accept treatment actively to cure Uremia in order to protect remained renal function. Peritoneal Dialysis and Hemodialysis are taken to treat this disease in the end stage of Uremia.
StageⅠ. Occurring Stage. Because this disease is a kind of hereditary disease, cysts have already formed when they were born. And normally, cysts cannot be found easily before patients are 20 years old due to the small size of cysts. If there are Polycystic Kidney Disease patients among family members, other family members should go to hospital for a check so as to observe cysts growing condition as early as possible. During this stage, patients should pay attention to daily life care.
Stage Ⅱ. Growing Stage. Cysts can grow faster when patients are in the range of 30 to 40 year old. This period is called growing stage medically. During this stage, observation on cysts growth should be strengthened. Western Medicine has no effective treatment to cure this disease in this stage, and it only can treat symptoms like Hypertension and other symptoms, which is absolutely passive. Actually, patients still need active treatment in this stage with the purpose of blocking or delaying cysts growing and prolonging patients’ life through the application of Chinese Medicine with stronger ability of activating blood and eliminating blood stasis. In another word, this stage can be the key stage for Chinese Medicine to delay cysts growing by activating blood and eliminating blood stasis.
Stage Ⅲ. Enlargement Stage. When patients are more than 40 years old, cysts can grow and enlarge further. From cysts increasing to more than 4cm to cysts rupture, this period is called Enlargement Stage. With cysts growing and increasing, more and more clinical symptoms like, waist ache, Albuminuria, Haematuria, increased blood pressure, etc, appear. Close observation is needed at this moment. As for treatment, Chinese Medicine can be taken to activate blood, eliminate blood stasis, excrete turbid and remove cystic fluid that can be harmful to renal function, in order to protect renal function.
Stage Ⅳ. Rupture Stage. If cysts keep growing, they may rupture under actions of external factors. Patients should be hospitalized to accept treatment once cysts rupture and control infections actively in order to prevent Septicemia and acute aggravation of renal function, which is helpful to treat other symptoms effectively.
Stage Ⅴ. Uremia Stage. During this stage, patients should accept treatment actively to cure Uremia in order to protect remained renal function. Peritoneal Dialysis and Hemodialysis are taken to treat this disease in the end stage of Uremia.
2016年10月27日星期四
Process of Renal Fibrosis in Polycystic Kidney Disease
How does cysts of PKD happen and why they can cause renal function injury?
PKD belongs to hereditary Kidney Diseases. Injuring process of PKD is mainly the
process of Renal Fibrosis.
Congenital gene mutation can cause cystic gene secretion which can enlarge cysts of Polycystic Kidney. Under the action of cystic wall, tubular basement membrane become abnormal, and continuously secrete growth factors, like EGF, TGF-β, IGF，etc, which can increase proliferation and secretion of epithelial cells on tubular wall of Polycystic Kidney. Proliferation of epithelial cells can cause renal tubule obstruction which can lead to fluid retention in upper tubular, and then cysts forms.
Besides, proliferation of epithelial cells can also lead to semi-obstruction at cysts neck, which causes difficulties for fluid to go out of human body. For this reason, cysts can keep growing.
With the development of Renal Fibrosis, synthesis of Extracellular Matrix increases, with less degradation, which causes an unbalance between ECM synthesis and degradation. Massive ECM deposit and accumulate in human body, resulting in Glomerular Sclerosis and renal tubular atrophy. Renal fibrosis tissue replaces healthy nephron gradually, and finally Renal Fibrosis forms.
According to pathogenesis of congenital Polycystic Kidney Disease, there are three main causes of cysts forming and developing. Firstly, cystic gene of PKD. Secondly, proliferation and secretion of renal tubule and epithelial cells on cyst wall. Thirdly, composition changes of ECM as well as development of Renal Fibrosis.
There are very few discomforts in the early stage of Polycystic Kidney Disease which is the main reason why the disease is always neglected by patients. Patients are suggested to accept treatment as early as possible, in order to avoid renal function injury and prevent Renal Fibrosis developing into cicatricial tissue, aggravating to Uremia.
Congenital gene mutation can cause cystic gene secretion which can enlarge cysts of Polycystic Kidney. Under the action of cystic wall, tubular basement membrane become abnormal, and continuously secrete growth factors, like EGF, TGF-β, IGF，etc, which can increase proliferation and secretion of epithelial cells on tubular wall of Polycystic Kidney. Proliferation of epithelial cells can cause renal tubule obstruction which can lead to fluid retention in upper tubular, and then cysts forms.
Besides, proliferation of epithelial cells can also lead to semi-obstruction at cysts neck, which causes difficulties for fluid to go out of human body. For this reason, cysts can keep growing.
With the development of Renal Fibrosis, synthesis of Extracellular Matrix increases, with less degradation, which causes an unbalance between ECM synthesis and degradation. Massive ECM deposit and accumulate in human body, resulting in Glomerular Sclerosis and renal tubular atrophy. Renal fibrosis tissue replaces healthy nephron gradually, and finally Renal Fibrosis forms.
According to pathogenesis of congenital Polycystic Kidney Disease, there are three main causes of cysts forming and developing. Firstly, cystic gene of PKD. Secondly, proliferation and secretion of renal tubule and epithelial cells on cyst wall. Thirdly, composition changes of ECM as well as development of Renal Fibrosis.
There are very few discomforts in the early stage of Polycystic Kidney Disease which is the main reason why the disease is always neglected by patients. Patients are suggested to accept treatment as early as possible, in order to avoid renal function injury and prevent Renal Fibrosis developing into cicatricial tissue, aggravating to Uremia.
2016年10月26日星期三
Polycystic Kidney Disease Treatment Methods
Ⅰ.General Treatment: In general, patients should keep optimistic firstly
after being diagnosed Polycystic Kidney Disease.
If normal life is not influenced, patients should keep a diet with less or no stimulating foods such as salty or spicy food and have a regular schedule, maintaining a steady and optimistic attitude. If being affected, besides of the above mentioned, patients should accept treatments as soon as possible. Otherwise, it will be too late to accept treatments if illness develops into Renal Function Failure which refers to Uremia.
Ⅱ.Cyst Decortications operation: This operation can reduce cystic pressure on renal parenchyma, which can prevent most of remaining renal units from being compressed and impaired further. It can also relieve renal ischemia and recover localized renal function, delaying the development of illness condition. The key to make operations succeed is to take operation as soon as possible, cyst decompression must be thorough, and small cysts as well as cysts in the deep kidney can’t be ignored. As for bilateral surgery, interval should be more than half a year generally. As for patients in end stage of Polycystic Kidney Disease, if they suffer from Renal Failure in the stage of azotemia and Uremia, no matter whether hypertension accompanied or not, they should not accept this operation. On the contrary, operation can worsen illness condition.
Ⅲ.Traditional Chinese Medicine Treatment: Presently, Traditional Chinese Medicine treatment has gained excellent effect on treating Polycystic Kidney by adopting conservative treatment, namely, external application of Traditional Chinese Medicine. Traditional Chinese Medicine considers Polycystic Kidney is the result of interaction of external and internal factors. In Traditional Chinese Medicine treatment, sac liquid is excreted gradually through the way of cascade diversion, so as to shrink cysts gradually. Conservative treatment has the incomparable treatment effect over Western Medicine, almost without side effect and makes disease less recurrence.
Ⅳ.Dialysis and Transplantation: Patients should accept dialysis treatment immediately and blood dialysis should be firstly chosen, when illness condition aggravate into End Stage Renal Failure. Surviving rate of kidney transplantation for Polycystic Kidney is some equal to other kidney transplantation for other reasons. But complications of Kidney Transplantation make postoperative management more difficult and affect the effect of kidney transplantation.
If normal life is not influenced, patients should keep a diet with less or no stimulating foods such as salty or spicy food and have a regular schedule, maintaining a steady and optimistic attitude. If being affected, besides of the above mentioned, patients should accept treatments as soon as possible. Otherwise, it will be too late to accept treatments if illness develops into Renal Function Failure which refers to Uremia.
Ⅱ.Cyst Decortications operation: This operation can reduce cystic pressure on renal parenchyma, which can prevent most of remaining renal units from being compressed and impaired further. It can also relieve renal ischemia and recover localized renal function, delaying the development of illness condition. The key to make operations succeed is to take operation as soon as possible, cyst decompression must be thorough, and small cysts as well as cysts in the deep kidney can’t be ignored. As for bilateral surgery, interval should be more than half a year generally. As for patients in end stage of Polycystic Kidney Disease, if they suffer from Renal Failure in the stage of azotemia and Uremia, no matter whether hypertension accompanied or not, they should not accept this operation. On the contrary, operation can worsen illness condition.
Ⅲ.Traditional Chinese Medicine Treatment: Presently, Traditional Chinese Medicine treatment has gained excellent effect on treating Polycystic Kidney by adopting conservative treatment, namely, external application of Traditional Chinese Medicine. Traditional Chinese Medicine considers Polycystic Kidney is the result of interaction of external and internal factors. In Traditional Chinese Medicine treatment, sac liquid is excreted gradually through the way of cascade diversion, so as to shrink cysts gradually. Conservative treatment has the incomparable treatment effect over Western Medicine, almost without side effect and makes disease less recurrence.
Ⅳ.Dialysis and Transplantation: Patients should accept dialysis treatment immediately and blood dialysis should be firstly chosen, when illness condition aggravate into End Stage Renal Failure. Surviving rate of kidney transplantation for Polycystic Kidney is some equal to other kidney transplantation for other reasons. But complications of Kidney Transplantation make postoperative management more difficult and affect the effect of kidney transplantation.
2016年10月21日星期五
How to Distinguish Renal Failure and Uremia Caused by PKD
If Polycystic Kidney Disease can not be controlled or treated effectively, it
may develop into Renal Insufficiency, or even Renal Failure and Uremia. Uremia
is not a independent disease name. Instead, it is a clinical syndrome of various
end stage Kidney Diseases. According to related tests and symptoms as well as
increasing physical indexes of serum creatinine and urea nitrogen, etc, disease
development can be divided into three stages—Renal Insufficiency compensatory
stage, azotemia stage and Uremia stage. Well, how to distinguish these three
stages?
In Renal Insufficiency compensatory stage, due to declined renal function, glomerular filtrating rate decreases, but serum creatinine is not more than 178umoI/L and blood urea nitrogen is less than 9mmoI/L. Patients have no symptoms in this stage. When serum creatinine is more than 178umoI/L and blood urea nitrogen is more than 9mmoI/L, and patients still have no clinical symptoms except tiredness, low appetite, and different degrees anemia, it means that this disease has developed into azotemia stage. Uremia stage refers to that glomerular filtrating rate decreases further, and serum creatinine is more than 445umoI/L as well as blood urea nitrogen is more than 20mmoI/L. In this stage, patients have obvious symptoms.
It is terrible if PKD develops into Uremia which is a great threat to human life. Therefore, PKD patients are suggested to receive effective treatment as early as possible, especially in Renal Insufficiency compensatory stage when cysts are still small.
In Renal Insufficiency compensatory stage, due to declined renal function, glomerular filtrating rate decreases, but serum creatinine is not more than 178umoI/L and blood urea nitrogen is less than 9mmoI/L. Patients have no symptoms in this stage. When serum creatinine is more than 178umoI/L and blood urea nitrogen is more than 9mmoI/L, and patients still have no clinical symptoms except tiredness, low appetite, and different degrees anemia, it means that this disease has developed into azotemia stage. Uremia stage refers to that glomerular filtrating rate decreases further, and serum creatinine is more than 445umoI/L as well as blood urea nitrogen is more than 20mmoI/L. In this stage, patients have obvious symptoms.
It is terrible if PKD develops into Uremia which is a great threat to human life. Therefore, PKD patients are suggested to receive effective treatment as early as possible, especially in Renal Insufficiency compensatory stage when cysts are still small.
2016年10月19日星期三
Diagnosis Methods of Adult Polycystic Kidney Disease
Presently, Adult PKD is mostly diagnosed by clinical symptoms and Imaging
Examination. In recent years, with the development of molecular genetic
technology, gene can be taken as a method to diagnose Adult PKD.
Clinical diagnosis: though there is not a common view on clinical diagnosis of Adult PKD, primary clinical diagnosis standard can be listed as follow: patients usually have clinical symptoms when they get around 40 years old. Clinical symptoms of swelling pain on waist and up back, Hypertension, Haematuria, abdominal masses, urinary tract infection and renal colic, complicated with urinary tract stone as well as Polycystic liver, Polycystic spleen and intracranial aneurysm can appear. Appearance of clinical symptoms means that cysts has already damaged renal parenchyma seriously. With time going on, this damage will be aggravated. Early clinical diagnosis always depends on familial history and imaging examination.
Imaging examination is the main method to diagnose Adult PKD.
Firstly, Ultrasonic Examination: ultrasonic examination is taken as the first choice to diagnose ADPKD, because it has a high sensitivity with no radioactivity and no trauma and it is also low-cost and convenient. Besides, ultrasonic examination is also used as an important method to make an prenatal diagnosis and to check the condition of patients' lineal consanguinity. Through Type-B ultrasonic examination, bilateral kidneys enlargement and irregular kidney shape can be found. Besides, round or oval cysts with various sizes can be found in kidneys, spreading the whole kidney. Cysts lose their smooth shape due to pressure to each other caused by each cyst. some patients may also be found Polycystic Liver or Polycystic Spleen through examination.
Secondly, CT : this is also an important method to diagnose ADPKD. Small cysts with diameter of 0.3cm to 0.5 cm can be found in bilateral kidneys. It has a significant role in making an early diagnosis of ADPKD. However, CT has radioactivity, so patients who suffer from early stage of PKD are not suggested to take this examination.
Thirdly, Other imaging examination: KUB and IVU can show enlarged kidney shadow, with irregular shape. Renal calices and renal pelvis can be changed normal shape and stretched as well as removed. Besides, cystoscopic urography and renoarteriography can also be used to diagnose ADPKD.
Gene diagnosis method: with continuous orientation and clone on gene of PKD patients, it is more possible to make an exact gene diagnosis of PKD and gene treatment of PKD. However, gene treatment is still in a start-up stage. Presently, there are two kinds of PKD diagnosis methods by gene: analysis on gene mutation and analysis on gene linkage.
Clinical diagnosis: though there is not a common view on clinical diagnosis of Adult PKD, primary clinical diagnosis standard can be listed as follow: patients usually have clinical symptoms when they get around 40 years old. Clinical symptoms of swelling pain on waist and up back, Hypertension, Haematuria, abdominal masses, urinary tract infection and renal colic, complicated with urinary tract stone as well as Polycystic liver, Polycystic spleen and intracranial aneurysm can appear. Appearance of clinical symptoms means that cysts has already damaged renal parenchyma seriously. With time going on, this damage will be aggravated. Early clinical diagnosis always depends on familial history and imaging examination.
Imaging examination is the main method to diagnose Adult PKD.
Firstly, Ultrasonic Examination: ultrasonic examination is taken as the first choice to diagnose ADPKD, because it has a high sensitivity with no radioactivity and no trauma and it is also low-cost and convenient. Besides, ultrasonic examination is also used as an important method to make an prenatal diagnosis and to check the condition of patients' lineal consanguinity. Through Type-B ultrasonic examination, bilateral kidneys enlargement and irregular kidney shape can be found. Besides, round or oval cysts with various sizes can be found in kidneys, spreading the whole kidney. Cysts lose their smooth shape due to pressure to each other caused by each cyst. some patients may also be found Polycystic Liver or Polycystic Spleen through examination.
Secondly, CT : this is also an important method to diagnose ADPKD. Small cysts with diameter of 0.3cm to 0.5 cm can be found in bilateral kidneys. It has a significant role in making an early diagnosis of ADPKD. However, CT has radioactivity, so patients who suffer from early stage of PKD are not suggested to take this examination.
Thirdly, Other imaging examination: KUB and IVU can show enlarged kidney shadow, with irregular shape. Renal calices and renal pelvis can be changed normal shape and stretched as well as removed. Besides, cystoscopic urography and renoarteriography can also be used to diagnose ADPKD.
Gene diagnosis method: with continuous orientation and clone on gene of PKD patients, it is more possible to make an exact gene diagnosis of PKD and gene treatment of PKD. However, gene treatment is still in a start-up stage. Presently, there are two kinds of PKD diagnosis methods by gene: analysis on gene mutation and analysis on gene linkage.
2016年10月16日星期日
Reasons That Can Cause PKD Patients Death
What are the reasons that can cause PKD patients death? Renal Insufficiency
which can be found in every age is the main cause of patients’ death. As for
patients older than 60, 45% of them may get the illness condition developed into
end stage Renal Failure. According to foreign investigation, the average time of
renal function injury developing into End Stage Renal Failure is about 10 years.
Once glomerular filtrating rate decreases to less than 50ml per minute, its
descent speed may be 5ml per minute in a year.
Renal Insufficiency is mainly caused by cysts which can compress renal parenchyma and reduce blood flow in renal blood vessel and effective filtrating rate. In addition, interstitium fibrosis and declined concentrated function and excreting ability caused by renal tubular pathological changes as well as renal blood vessel sclerosis caused by Hypertension can block toxin being filtrated, and then Renal Insufficiency appears.
Besides, other factors may also affect renal function aggravated speed.
Firstly, gene: PKD patients who suffer from gene mutation will die 10 years earlier than patients who do not suffer from gene mutation.
Secondly, inheritance factor: patients who inherit this disease from mother will die earlier than patients who get this disease from father.
Thirdly, gender: female can be later than male, except for patients who suffer from Liver Cyst at the same time.
Fourthly, Haematuria, Albuminuria as well as urinary tract infection and other infections can aggravate renal function. Besides, pregnancy can also affect renal function.
These factors can be independent or co-existent, both of which can lead to renal function injury.
All the above factors may cause patients death. Patients should pay more attention on these factors. The key reason of PKD recurrence is that renal fibrosis can not be blocked from its root cause and renal function can not be protected effectively. As for treatment of PKD, Micro-Chinese Medicine Osmotherapy is an effective treatment to treat PKD through activating blood and dredging channels, removing blood stasis and eliminating toxin as well as repairing and renewing. It has helped many PKD patients to live a normal life with illness.
Renal Insufficiency is mainly caused by cysts which can compress renal parenchyma and reduce blood flow in renal blood vessel and effective filtrating rate. In addition, interstitium fibrosis and declined concentrated function and excreting ability caused by renal tubular pathological changes as well as renal blood vessel sclerosis caused by Hypertension can block toxin being filtrated, and then Renal Insufficiency appears.
Besides, other factors may also affect renal function aggravated speed.
Firstly, gene: PKD patients who suffer from gene mutation will die 10 years earlier than patients who do not suffer from gene mutation.
Secondly, inheritance factor: patients who inherit this disease from mother will die earlier than patients who get this disease from father.
Thirdly, gender: female can be later than male, except for patients who suffer from Liver Cyst at the same time.
Fourthly, Haematuria, Albuminuria as well as urinary tract infection and other infections can aggravate renal function. Besides, pregnancy can also affect renal function.
These factors can be independent or co-existent, both of which can lead to renal function injury.
All the above factors may cause patients death. Patients should pay more attention on these factors. The key reason of PKD recurrence is that renal fibrosis can not be blocked from its root cause and renal function can not be protected effectively. As for treatment of PKD, Micro-Chinese Medicine Osmotherapy is an effective treatment to treat PKD through activating blood and dredging channels, removing blood stasis and eliminating toxin as well as repairing and renewing. It has helped many PKD patients to live a normal life with illness.
2016年10月15日星期六
Categories of Polycystic Kidney Disease
Polycystic Kidney Disease (PKD) belongs to a kind of hereditary disease.
According the Genetics, PKD can be categorized as autosomal dominant PKD and
recessive PKD. And autosomal dominant PKD is more universal amid patients.
ADPKD belongs to autosomal dominate inheritance with characteristic of familial aggregation. Both male and female can get this disease with equal possibility. This disease can also inherit for generations.
ADPKD is also known as adult PKD, which is very common. With the gradual penetration to this disease, prognosis for this disease is improved apparently.
ARPKD belongs to autosomal recessive inheritance, which is also known as fetus PKD. Fetus’ parents rarely have the same disease history. This type is really seldom seen among PKD patients, and most of sick children die soon after their birth. Only very few of them who suffer from lighter illness condition can survive till to childhood, or even adulthood.
Micro-Chinese Medicine Osmotherapy can treat PKD effectively through the methods of activating blood, removing blood stasis in channels and eliminating toxin in body. Active substances of Chinese Medicine can protect remained healthy nephron and recover injured renal cells after they entering into renal lesion. It can treat PKD effectively with no operation and no side effect.
ADPKD belongs to autosomal dominate inheritance with characteristic of familial aggregation. Both male and female can get this disease with equal possibility. This disease can also inherit for generations.
ADPKD is also known as adult PKD, which is very common. With the gradual penetration to this disease, prognosis for this disease is improved apparently.
ARPKD belongs to autosomal recessive inheritance, which is also known as fetus PKD. Fetus’ parents rarely have the same disease history. This type is really seldom seen among PKD patients, and most of sick children die soon after their birth. Only very few of them who suffer from lighter illness condition can survive till to childhood, or even adulthood.
Micro-Chinese Medicine Osmotherapy can treat PKD effectively through the methods of activating blood, removing blood stasis in channels and eliminating toxin in body. Active substances of Chinese Medicine can protect remained healthy nephron and recover injured renal cells after they entering into renal lesion. It can treat PKD effectively with no operation and no side effect.
2016年10月13日星期四
Typical Case of Polycystic Kidney Disease
Patient Name: Zhou Ping
Gender: Female
Age: 53
Province: Zhangjiakou, Hebei Province
Diagnosis: Polycystic Kidney Disease, Chronic Renal Insufficiency in Renal Failure Stage, Nephrotic Anemia, Nephrotic Hypertension, and Polycystic Liver Disease.
Physical Examination in Shijiazhuang Kidney Disease Hospital: patient had symptoms of nausea, vomiting, tiredness and low appetite.
Blood pressure: 180/120mmHg
Type-B Ultrasonic result, right kidney: 28×9.5×9.2cm; left kidney: 30×10×9.5cm
Renal function:Scr642umol/L，BUN27mmol/L
Electrolyte: cl120mmol/L，co2cp15mmol/L
Routine Blood Test: Hb80g/L
Treatment and effect: patient was given Micro-Chinese Medicine Osmotherapy to treat her disease. Five days later, symptoms of nausea and vomiting disappear, and patient began to have a better appetite after seven-day treatment. Ten days later, tiredness is relived and blood pressure was controlled in 130/80mmHg.
Test results of 20days later, renal function: Scr400umol/L，BUN19mmol/L; electrolyte: cl110mmol/L，co2cp21mmol/L; routine blood test: Hb95g/L; right Kidney: 20×7.2×7.0cm; left kidney: 19×7.0×7.5cm
Patient left hospital to home for consolidation treatment.
Returning visit after half a year, renal function: Scr178umol/L，BUN8.5mmol/L; electrolyte: co2cp25mmol/L; routine blood test: Hb110g/L; right kidney: 10×5.0×5.0cm; left kidney: 10.5×5.0×5.5cm
Expert comment: Renal Failure that patient suffered from was developed gradually from Polycystic Kidney Disease which usually happens among patients at 35 to 40 years old. With cysts growing, they can compress nephron, which can lead to renal ischemia and anoxia as well as function decline. Once some certain number nephron function is damaged or disappeared, this disease can develop into Renal Insufficiency, or even Uremia, causing a series of complications of anemia, acidosis, and gastrointestinal functional disorder and so on. Micro-Chinese Medicine can improve blood circulation on cyst wall, recycle cyst fluid and reduce cysts, which is helpful to reduce cystic pressure on nephron and recover injured nephron. Through this method, renal function can be recovered and complications can be relived at the same time.
Gender: Female
Age: 53
Province: Zhangjiakou, Hebei Province
Diagnosis: Polycystic Kidney Disease, Chronic Renal Insufficiency in Renal Failure Stage, Nephrotic Anemia, Nephrotic Hypertension, and Polycystic Liver Disease.
Physical Examination in Shijiazhuang Kidney Disease Hospital: patient had symptoms of nausea, vomiting, tiredness and low appetite.
Blood pressure: 180/120mmHg
Type-B Ultrasonic result, right kidney: 28×9.5×9.2cm; left kidney: 30×10×9.5cm
Renal function:Scr642umol/L，BUN27mmol/L
Electrolyte: cl120mmol/L，co2cp15mmol/L
Routine Blood Test: Hb80g/L
Treatment and effect: patient was given Micro-Chinese Medicine Osmotherapy to treat her disease. Five days later, symptoms of nausea and vomiting disappear, and patient began to have a better appetite after seven-day treatment. Ten days later, tiredness is relived and blood pressure was controlled in 130/80mmHg.
Test results of 20days later, renal function: Scr400umol/L，BUN19mmol/L; electrolyte: cl110mmol/L，co2cp21mmol/L; routine blood test: Hb95g/L; right Kidney: 20×7.2×7.0cm; left kidney: 19×7.0×7.5cm
Patient left hospital to home for consolidation treatment.
Returning visit after half a year, renal function: Scr178umol/L，BUN8.5mmol/L; electrolyte: co2cp25mmol/L; routine blood test: Hb110g/L; right kidney: 10×5.0×5.0cm; left kidney: 10.5×5.0×5.5cm
Expert comment: Renal Failure that patient suffered from was developed gradually from Polycystic Kidney Disease which usually happens among patients at 35 to 40 years old. With cysts growing, they can compress nephron, which can lead to renal ischemia and anoxia as well as function decline. Once some certain number nephron function is damaged or disappeared, this disease can develop into Renal Insufficiency, or even Uremia, causing a series of complications of anemia, acidosis, and gastrointestinal functional disorder and so on. Micro-Chinese Medicine can improve blood circulation on cyst wall, recycle cyst fluid and reduce cysts, which is helpful to reduce cystic pressure on nephron and recover injured nephron. Through this method, renal function can be recovered and complications can be relived at the same time.
2016年10月12日星期三
Symptoms in Late Stage Polycystic Kidney Disease
Most PKD patients seldom have symptoms in early stage of Polycystic Kidney
Disease due to concealed characteristic of this disease. But if this disease
develops into late stage, cysts grow gradually and compress kidneys, causing
different symptoms. There are several symptoms of late stage PKD in following
passage.
Firstly, cysts are in round shape with various sizes.
Secondly, Haematuria: due to growing size of cysts, cyst rupture may happen, and then Haematuria appear. Cyst rupture may be mainly caused by strenuous exercise or excessive tiredness. Once this situation appears, patients should be sent to hospital as quickly as possible in order to avoid cyst secondary rupture and illness condition worsening.
Thirdly, some complications such as retinopathy may happen. High Blood Pressure may lead to eyeground arterial sclerosis, which can reduce blood supply to retina. Besides, massive Haematuria can cause sudden hemoglobin decline, which can worsen optic neuropathy and blood supply condition, resulting in secondary optic atrophy.
Fourthly, with cysts growing, kidney volume increases to 10 times with normal ones. Kidney has abnormal shape such as malformation of renal calices and renal pelvis.
Fifth, renal function can be damaged completely with cysts of PKD growing, which can lead to Renal Insufficiency and Uremia.
PKD patients should accept timely and active treatment in order to prevent illness condition developing into Renal Failure or even Uremia. As for treatment of PKD, Micro-Chinese Medicine Osmotherapy can treat PKD effectively through three steps of activating blood and dredging channels, removing blood stasis and eliminating toxin, repairing and renewing. This treatment can treat PKD from its root cause. PKD patients can live healthily with this disease, if cysts growth can be controlled effectively.
Firstly, cysts are in round shape with various sizes.
Secondly, Haematuria: due to growing size of cysts, cyst rupture may happen, and then Haematuria appear. Cyst rupture may be mainly caused by strenuous exercise or excessive tiredness. Once this situation appears, patients should be sent to hospital as quickly as possible in order to avoid cyst secondary rupture and illness condition worsening.
Thirdly, some complications such as retinopathy may happen. High Blood Pressure may lead to eyeground arterial sclerosis, which can reduce blood supply to retina. Besides, massive Haematuria can cause sudden hemoglobin decline, which can worsen optic neuropathy and blood supply condition, resulting in secondary optic atrophy.
Fourthly, with cysts growing, kidney volume increases to 10 times with normal ones. Kidney has abnormal shape such as malformation of renal calices and renal pelvis.
Fifth, renal function can be damaged completely with cysts of PKD growing, which can lead to Renal Insufficiency and Uremia.
PKD patients should accept timely and active treatment in order to prevent illness condition developing into Renal Failure or even Uremia. As for treatment of PKD, Micro-Chinese Medicine Osmotherapy can treat PKD effectively through three steps of activating blood and dredging channels, removing blood stasis and eliminating toxin, repairing and renewing. This treatment can treat PKD from its root cause. PKD patients can live healthily with this disease, if cysts growth can be controlled effectively.
2016年10月7日星期五
Reasons of Polycystic Kidney Disease
Polycystic Kidney Disease is mainly caused by hereditary factor which is
inherited from either of parent’s gene. Besides hereditary factor, there are
still other factors that can cause Polycystic Kidney Disease.
Firstly, we should know that what congenital Polycystic Kidney Disease is. Some people think that Polycystic Kidney Disease is mainly caused by existed renal tubular diverticulum. Cyst fluid chemical composition of Adult congenital Polycystic Kidney Disease is similar with plasma ultrafiltrate. It was tested that there are 20 secretion circles of cyst fluid. Inner diameter of cyst is 0.5 to 1cm normally, or even 3 to 4 cm.
The most acceptable cause of Polycystic Kidney Disease is renal ischemia. Typically, cyst wall of Polycystic Kidney is very thin in transparent form. After infected for many times, Cyst wall will become thick, fibrosis or even calcification. With cysts of PKD patients growing, they can compress renal parenchyma. However, it is not so severe to damage renal function.
Specialist on Kidney Disease points that congenital Polycystic Kidney Disease belongs to tumor actually. The older patients are, the higher incidence is. Pathogenesis of PKD is not researched clearly yet. Maybe it is related with congenital glomerular and renal tubular structural abnormality as well as acquired trauma infection.
Knowing about some common knowledge is helpful for patients to prevent this disease happening. Person who has a familial history of PKD should avoid infection and cold in order to reduce incidence of Polycystic Kidney Disease.
Firstly, we should know that what congenital Polycystic Kidney Disease is. Some people think that Polycystic Kidney Disease is mainly caused by existed renal tubular diverticulum. Cyst fluid chemical composition of Adult congenital Polycystic Kidney Disease is similar with plasma ultrafiltrate. It was tested that there are 20 secretion circles of cyst fluid. Inner diameter of cyst is 0.5 to 1cm normally, or even 3 to 4 cm.
The most acceptable cause of Polycystic Kidney Disease is renal ischemia. Typically, cyst wall of Polycystic Kidney is very thin in transparent form. After infected for many times, Cyst wall will become thick, fibrosis or even calcification. With cysts of PKD patients growing, they can compress renal parenchyma. However, it is not so severe to damage renal function.
Specialist on Kidney Disease points that congenital Polycystic Kidney Disease belongs to tumor actually. The older patients are, the higher incidence is. Pathogenesis of PKD is not researched clearly yet. Maybe it is related with congenital glomerular and renal tubular structural abnormality as well as acquired trauma infection.
Knowing about some common knowledge is helpful for patients to prevent this disease happening. Person who has a familial history of PKD should avoid infection and cold in order to reduce incidence of Polycystic Kidney Disease.
2016年10月5日星期三
Clinical Meaning of Serum Creatinine Test
Normally, serum creatinine is not affected by external factors like diet,
high catabolism and so on. On the condition that exogenous creatinine intake is
steady and internal generation is constant, concentration of serum creatinine
mostly depend on Glomerular filtrating rate. However, serum creatinine is not
equal to creatinine clearance rate which is more sensitive than the former one.
During renal function compensatory stage, creatinine clearance rate reduces but
serum creatinine is normal. Only if glomerular filtrating rate decreases to less
than 50%, serum creatinine will increase rapidly. Therefore, when serum
creatinine is obviously higher than normal condition, renal function has already
been damaged greatly. Because creatinine clearance rate is still related with
glomerular concentrated function, serum creatinine is a significant index to
reflect glomerular function once renal concentrated function in injured.
Normally, serum creatinine value of male should be in the range of 53 to 106gmol/L or 0.6 to 1.2rug/d1, and female value should be 44.2 to 97.2gmol/L or 0.5 to 1.1rug/d1. Because internal generation of creatinine is related with muscle amount, serum creatinine value of people with well-developed muscle may be high to 130gmol/L, while for very thin people, creatinine value may be only 26.5gmol/L. if patients serum creatinine is higher than 132gmol/L, their glomerular function may have been greatly damaged. Besides emaciation, due to the assimilation of increased glomerular filtrating rate and fetus, people who are pregnant usually have a lower serum creatinine value than normal person.
Normally, very tiny creatinine is secreted by renal tubule, and some may diffuse into enteric cavity. As for Uremia patients, renal tubule secretion increases greatly, with 16% to 60% creatinine entering into enteric cavity. Reproduction of streptococcus and enterococcus in upper gastrointestinal tract can produce creatinine lyase which can degrade creatinine. For this reason, as for some Uremia patients, concentration of serum creatinine and urine creatinine as well as internal creatinine clearance rate may fluctuate.
Normally, serum creatinine value of male should be in the range of 53 to 106gmol/L or 0.6 to 1.2rug/d1, and female value should be 44.2 to 97.2gmol/L or 0.5 to 1.1rug/d1. Because internal generation of creatinine is related with muscle amount, serum creatinine value of people with well-developed muscle may be high to 130gmol/L, while for very thin people, creatinine value may be only 26.5gmol/L. if patients serum creatinine is higher than 132gmol/L, their glomerular function may have been greatly damaged. Besides emaciation, due to the assimilation of increased glomerular filtrating rate and fetus, people who are pregnant usually have a lower serum creatinine value than normal person.
Normally, very tiny creatinine is secreted by renal tubule, and some may diffuse into enteric cavity. As for Uremia patients, renal tubule secretion increases greatly, with 16% to 60% creatinine entering into enteric cavity. Reproduction of streptococcus and enterococcus in upper gastrointestinal tract can produce creatinine lyase which can degrade creatinine. For this reason, as for some Uremia patients, concentration of serum creatinine and urine creatinine as well as internal creatinine clearance rate may fluctuate.
2016年10月1日星期六
Developing Process of Adult Polycystic Kidney Disease
In the early stage Adult PKD, cysts are still small, so patients seldom have
obvious symptoms in this stage. With cysts growing and increasing, they can
compress surrounding renal tissue greatly. Then obvious symptoms appear. Pain on
waist usually happens firstly in early stage, but it is usually neglected by
most patients and no treatment can be taken to treat this symptom. Growing cysts
can replace more and more normal renal tissue, causing larger pressure on
surrounding renal tissue, and then End Stage Renal Failure appears.
Ⅰ. What is the hereditary regulation of Adult PKD?
Adult PKD follows the regulation of autosomal dominant inheritance, with equal incidence to both male and female. Each of the parents suffers from this disease, each of their children can get this disease at a risk of 50%, and this number can increase to 75% if both parents have this disease. Children who do not inherit PKD do not carry cystic gene, and their later generation won’t have this disease if they marry with person who do not suffer from PKD. Besides inherited from parents, patients who get this disease through gene mutation are rarely seen.
Ⅱ. Does PKD have a serious illness condition when it happens?
Generally, there are no obvious symptoms in early stage PKD. For this reason, most patients are not diagnosed as PKD in this stage. Common primary symptoms that may appear in early stage of PKD are High Blood Pressure, Haematuria, bellyache, and sometimes Urinary tract infection and Kidney Stone can be found among primary symptoms.
Each disease develops from slowly and lightly to rapidly and seriously, and PKD is no exception. Due to strong compensatory ability of kidney, there are seldom obvious clinical symptoms when kidney is injured by cysts or other external factors in the early stage. Patients can live, work and study normally.
Ⅲ. How about the process of PKD developing into Uremia?
PKD is a kind of disease that so many cysts are growing in whole kidney. These cysts are growing with age, causing pressure on kidneys, which can damage renal structure and reduce nephron number. Finally, kidneys are so injured that they can not maintain body’s normal life. At this moment, Uremia happens.
More exactly, the process of Renal Failure and Uremia is also the process of Renal Fibrosis, and Renal Failure and Uremia is the result of more than 50% kidney fibrosis.
Specialists on Kidney Disease point out that the earlier treatment is taken, the better therapeutic effect can get. The best treating timing is before renal function injury. Renal Failure and Uremia can be avoided completely if cysts of PKD growth can be removed or controlled effectively in the early stage.
Ⅰ. What is the hereditary regulation of Adult PKD?
Adult PKD follows the regulation of autosomal dominant inheritance, with equal incidence to both male and female. Each of the parents suffers from this disease, each of their children can get this disease at a risk of 50%, and this number can increase to 75% if both parents have this disease. Children who do not inherit PKD do not carry cystic gene, and their later generation won’t have this disease if they marry with person who do not suffer from PKD. Besides inherited from parents, patients who get this disease through gene mutation are rarely seen.
Ⅱ. Does PKD have a serious illness condition when it happens?
Generally, there are no obvious symptoms in early stage PKD. For this reason, most patients are not diagnosed as PKD in this stage. Common primary symptoms that may appear in early stage of PKD are High Blood Pressure, Haematuria, bellyache, and sometimes Urinary tract infection and Kidney Stone can be found among primary symptoms.
Each disease develops from slowly and lightly to rapidly and seriously, and PKD is no exception. Due to strong compensatory ability of kidney, there are seldom obvious clinical symptoms when kidney is injured by cysts or other external factors in the early stage. Patients can live, work and study normally.
Ⅲ. How about the process of PKD developing into Uremia?
PKD is a kind of disease that so many cysts are growing in whole kidney. These cysts are growing with age, causing pressure on kidneys, which can damage renal structure and reduce nephron number. Finally, kidneys are so injured that they can not maintain body’s normal life. At this moment, Uremia happens.
More exactly, the process of Renal Failure and Uremia is also the process of Renal Fibrosis, and Renal Failure and Uremia is the result of more than 50% kidney fibrosis.
Specialists on Kidney Disease point out that the earlier treatment is taken, the better therapeutic effect can get. The best treating timing is before renal function injury. Renal Failure and Uremia can be avoided completely if cysts of PKD growth can be removed or controlled effectively in the early stage.
2016年9月30日星期五
Case Analysis of Bilateral Polycystic Kidney Disease
Patient: Chen Linzhi
Gender: Female
Age: 38
Province: Shanxi Province
Diagnosis: Bilateral Polycystic Kidney Disease
Symptoms before she went to our hospital: patients have unknown pain on waist five years ago, and she didn’t pay attention on this symptom. Later, pain become worsening and painful feeling did not relieve effectively after simple treatment. In December, 2003, patient got a sudden serious pain on waist due to excessive tiredness, and then Haematuria appeared. Though Type-B Ultrasonic examination, liquid shadow with various sizes can be found in bilateral kidneys. Serum creatinine is 899umol/L. patient was diagnosed as Bilateral Polycystic Kidney Disease. Patient found the information of Shijiazhuang Kidney Disease Hospital through website, and she came to our hospital for treatment later.
Treatment and Effect: after 10-day Micro-Chinese Medicine Osmotherapy treatment, patient’s renal ability of excreting toxin increased, and serum creatinine became 870umol0/L.
Patient brought medicine home for consolidating treatment.
Secondary check after one month: serum creatinine 835umol/L. through Type-B Ultrasonic examination, bilateral cysts became smaller. Presently, symptoms of pain on waist and Haematuria disappear. Patient’s illness condition is steady and recovered gradually.
Expert Comment: Polycystic Kidney Disease is a kind of disease with hereditary feature, developing with age. Traditional surgical operation can only remove big cysts, which will leave more space for small cysts to grow. These small cysts can grow more rapidly without pressure from big cysts. Finally, they can damage kidney for a second time. Therefore, renal injury will be aggravated further.
Micro-Chinese Medicine can treat PKD without surgical operation. This treatment can improve blood circulation on cyst wall and recycle cyst internal fluid, which can reduce cyst size. Through this way, it can relieve cystic pressure on surrounding healthy renal tissue and repair renal function. Then symptoms of pain on waist and Haematuria disappear.
Gender: Female
Age: 38
Province: Shanxi Province
Diagnosis: Bilateral Polycystic Kidney Disease
Symptoms before she went to our hospital: patients have unknown pain on waist five years ago, and she didn’t pay attention on this symptom. Later, pain become worsening and painful feeling did not relieve effectively after simple treatment. In December, 2003, patient got a sudden serious pain on waist due to excessive tiredness, and then Haematuria appeared. Though Type-B Ultrasonic examination, liquid shadow with various sizes can be found in bilateral kidneys. Serum creatinine is 899umol/L. patient was diagnosed as Bilateral Polycystic Kidney Disease. Patient found the information of Shijiazhuang Kidney Disease Hospital through website, and she came to our hospital for treatment later.
Treatment and Effect: after 10-day Micro-Chinese Medicine Osmotherapy treatment, patient’s renal ability of excreting toxin increased, and serum creatinine became 870umol0/L.
Patient brought medicine home for consolidating treatment.
Secondary check after one month: serum creatinine 835umol/L. through Type-B Ultrasonic examination, bilateral cysts became smaller. Presently, symptoms of pain on waist and Haematuria disappear. Patient’s illness condition is steady and recovered gradually.
Expert Comment: Polycystic Kidney Disease is a kind of disease with hereditary feature, developing with age. Traditional surgical operation can only remove big cysts, which will leave more space for small cysts to grow. These small cysts can grow more rapidly without pressure from big cysts. Finally, they can damage kidney for a second time. Therefore, renal injury will be aggravated further.
Micro-Chinese Medicine can treat PKD without surgical operation. This treatment can improve blood circulation on cyst wall and recycle cyst internal fluid, which can reduce cyst size. Through this way, it can relieve cystic pressure on surrounding healthy renal tissue and repair renal function. Then symptoms of pain on waist and Haematuria disappear.
2016年9月29日星期四
Urinary Tract Infection of Polycystic Kidney Disease
Urinary tract infection which includes cystitis, nephropyelitis, cyst
infection and perinephric abscess is a common complication of PKD patients.
About 20% patients get urinary tract infection as first symptom among clinical
symptoms, and 50% t0 70% patients have urinary tract infection at least one time
during their life, especially for female patients. It has been observed in the
past that one third PKD patients who accept chronic dialysis have the symptom of
urinary tract infection. Though antibiotic is taken to deal with infection,
which can delay illness development, patients still can get perinephric abscess,
or even sometimes patients may die. There are some difficulties in treat
Polycystic Kidney Disease, especially in the aspects of preventing and treating
urinary tract infection.
Patients who suffer from PKD, complicated with cystitis, are mainly expressed by urgent urination, Odynuria and pain on pubis arch area. If infection has involved upper urinary tract, patients may have continuous high fever and waist pain. Clinically, it is some difficult to distinguish nephropyelitis from cyst infection. It is beneficial to diagnose nephropyelitis if urine culture shows positive with increasing blood leukocyte number and quick response to anti-infection treatment. While positive blood culture and pressing pain always refers to cyst infection.
When patients suspect themselves of urinary tract infection, they should accept an imaging examination. Abdominal plain film can show the position, size and numbers of urinary system stones as well as perinephric abscess. CT examination has a better sensitivity of testing perinephric abscess. As for PKD patients suffering from urinary tract infection, equipment inspection can increase the possibility of patients getting blood poisoning. For this reason, Retrograde Pyelography should be avoided.
Choosing effective antibiotics is the key of treating this disease successfully. As for patients who suffer from recurrent urinary tract infection, antibiotics are helpful to prevent infection. If equipment inspection on urinary tract is inevitable, patients should take proper antibiotic to prevent infection in 24 hours before or after treatment.
Patients who suffer from PKD, complicated with cystitis, are mainly expressed by urgent urination, Odynuria and pain on pubis arch area. If infection has involved upper urinary tract, patients may have continuous high fever and waist pain. Clinically, it is some difficult to distinguish nephropyelitis from cyst infection. It is beneficial to diagnose nephropyelitis if urine culture shows positive with increasing blood leukocyte number and quick response to anti-infection treatment. While positive blood culture and pressing pain always refers to cyst infection.
When patients suspect themselves of urinary tract infection, they should accept an imaging examination. Abdominal plain film can show the position, size and numbers of urinary system stones as well as perinephric abscess. CT examination has a better sensitivity of testing perinephric abscess. As for PKD patients suffering from urinary tract infection, equipment inspection can increase the possibility of patients getting blood poisoning. For this reason, Retrograde Pyelography should be avoided.
Choosing effective antibiotics is the key of treating this disease successfully. As for patients who suffer from recurrent urinary tract infection, antibiotics are helpful to prevent infection. If equipment inspection on urinary tract is inevitable, patients should take proper antibiotic to prevent infection in 24 hours before or after treatment.
2016年9月28日星期三
Some Questions of Polycystic Kidney Disease
Ⅰ.How does PKD treatment develop?
The reason why Polycystic Kidney Disease patients have higher serum creatinine is that patients’ cysts growing bigger gradually, which canl damage renal inherent cells, start the process of renal fibrosis and aggravate inherent cells injury furthrt. Damaged inherent cells can shrink blood vessel, which can cause High Blood Pressure. Because epithelial cells in inherent cells get damaged, they can’t prevent blood protein leakage,and then Albuminuria occurs. When inherent cells are so injured that they can not excrete more toxins, serum creatinine increases.
Ⅱ.What is the key point of causing Polycystic Kidney Disease?
Inherent cells injury caused by renal fibrosis is the real cause of Polycystic Kidney Disease. High Blood Pressure, Proteinuria, Blood Urine caused by inherent cells injury are symptoms of this disease. If patients want to cure High Blood Pressure, Proteinuria, Blood Urine, they need to cure real cause of this disease firstly.
No matter what kinds of therapeutic methods are taken, real cause of Polycystic Kidney Disease should be treated firstly. Treating disease must block Renal Fibrosis which can damage renal inherent cells. As long as the process of renal fibrosis is blocked and damaged inherent cells get repaired, symptoms of Albuminuria and Haematuria can disappear and cysts can be shrunk gradually.
The reason why disease continues for a long term is that effective treatment is not taken to block Renal Fibrosis.So the real reason why disease can’t be cured is that medicine can’t prevent the renal fibrosis from damaging renal inherent cells.
Ⅲ.How to treat Polycystic Kidney effectively?
Firstly, illness condition caused by renal inherent cells injury should be controlled firstly.
Secondly, taking proper treatment to reduce cyst fluid can relieve further pressure on renal inherent cells. Then function of inherent cells can be recovered gradually.
Thirdly, repair injured inherent cells, supply requested substances for cell recover and activate the kidney self-repair function.
The reason why Polycystic Kidney Disease patients have higher serum creatinine is that patients’ cysts growing bigger gradually, which canl damage renal inherent cells, start the process of renal fibrosis and aggravate inherent cells injury furthrt. Damaged inherent cells can shrink blood vessel, which can cause High Blood Pressure. Because epithelial cells in inherent cells get damaged, they can’t prevent blood protein leakage,and then Albuminuria occurs. When inherent cells are so injured that they can not excrete more toxins, serum creatinine increases.
Ⅱ.What is the key point of causing Polycystic Kidney Disease?
Inherent cells injury caused by renal fibrosis is the real cause of Polycystic Kidney Disease. High Blood Pressure, Proteinuria, Blood Urine caused by inherent cells injury are symptoms of this disease. If patients want to cure High Blood Pressure, Proteinuria, Blood Urine, they need to cure real cause of this disease firstly.
No matter what kinds of therapeutic methods are taken, real cause of Polycystic Kidney Disease should be treated firstly. Treating disease must block Renal Fibrosis which can damage renal inherent cells. As long as the process of renal fibrosis is blocked and damaged inherent cells get repaired, symptoms of Albuminuria and Haematuria can disappear and cysts can be shrunk gradually.
The reason why disease continues for a long term is that effective treatment is not taken to block Renal Fibrosis.So the real reason why disease can’t be cured is that medicine can’t prevent the renal fibrosis from damaging renal inherent cells.
Ⅲ.How to treat Polycystic Kidney effectively?
Firstly, illness condition caused by renal inherent cells injury should be controlled firstly.
Secondly, taking proper treatment to reduce cyst fluid can relieve further pressure on renal inherent cells. Then function of inherent cells can be recovered gradually.
Thirdly, repair injured inherent cells, supply requested substances for cell recover and activate the kidney self-repair function.
2016年9月24日星期六
Symptoms Caused by Polycystic Kidney Disease
Most PKD patients do not have clinical symptoms in the early stage. While in
end stage, due to cysts as well as increasing cyst internal pressure and
infections, most patients can get the following symptoms:
1. Albuminuria: generally, protein content in urine is tiny, no more than 2g each 24 hours. Nephrotic Syndrome seldom occurs.
2. Abdominal masses: this is also the main reason why patients do to hospital for a check. Enlarged kidneys can be touched among 60% to 80% PKD patients. Normally, the larger kidneys are, the lower renal function is.
3. High Blood Pressure: cysts compress kidneys, which can lead to renal ischemia and increase renin secretion, causing High Blood Pressure. When renal function is normal, more than 50% patients can get High Blood Pressure. This number can be much higher when renal function declines.
4. Haematuria: this symptoms can be expressed by microscopic Haematuria and gross Haematuria, occurs periodically. Patients usually feel really painful when Haematuria appears, and this pain can be more serious after strenuous exercise, trauma and infection. There are a large amount of arteries under cyst wall. Due to growing pressure or complicated infection, blood vessel of cyst wall can bleed for excessive tensility.
5. Renal function decline: growing cysts will replace and compress normal renal tissue, which can reduce healthy renal tissue obviously, causing progressive decline of renal function.
6. Pain or discomfort on waist and abdomen: kidney enlargement can increase tensility of renal capsule. Besides, more cysts in kidneys can increase water content of kidneys, which can make kidney heavier, leading waist pain.
1. Albuminuria: generally, protein content in urine is tiny, no more than 2g each 24 hours. Nephrotic Syndrome seldom occurs.
2. Abdominal masses: this is also the main reason why patients do to hospital for a check. Enlarged kidneys can be touched among 60% to 80% PKD patients. Normally, the larger kidneys are, the lower renal function is.
3. High Blood Pressure: cysts compress kidneys, which can lead to renal ischemia and increase renin secretion, causing High Blood Pressure. When renal function is normal, more than 50% patients can get High Blood Pressure. This number can be much higher when renal function declines.
4. Haematuria: this symptoms can be expressed by microscopic Haematuria and gross Haematuria, occurs periodically. Patients usually feel really painful when Haematuria appears, and this pain can be more serious after strenuous exercise, trauma and infection. There are a large amount of arteries under cyst wall. Due to growing pressure or complicated infection, blood vessel of cyst wall can bleed for excessive tensility.
5. Renal function decline: growing cysts will replace and compress normal renal tissue, which can reduce healthy renal tissue obviously, causing progressive decline of renal function.
6. Pain or discomfort on waist and abdomen: kidney enlargement can increase tensility of renal capsule. Besides, more cysts in kidneys can increase water content of kidneys, which can make kidney heavier, leading waist pain.
2016年9月21日星期三
Can Season Affect PKD Illness Condition
In spring, everything has a new life, and this is a season favorable for
Kidney Disease patients’ recovery. But there is too much wind in spring, which
is easy to cause wind-pathogen. In hot summer, patients are easy to be injured
by fire-pathogen. Besides, it is hot and wet in summer and heat or dampness can
also damage human body. Autumn is really dry, so patients should care about
dryness which can damage Yin of lung and kidney. Winter is cold, which can make
Kidney Disease patients get Yang injury easily.
From clinical viewpoint, the hottest and coldest seasons are both unfavorable for patients’ illness condition. Hot weather is easy to cause various infections like urinary tract infection, gastrointestinal tract infection and upper respiratory tract infection and so on, all of which can speed up the development of PKD illness condition directly or indirectly. PKD patients, especially patients in third or fourth stage, usually have much lower immunity. They are easy to catch a cold, which can not only worsen PKD illness condition, but also affect blood pressure condition.
Specialists on Kidney Disease note that: as for PKD patients, the best treating timings are spring and autumn, which can reduce disadvantages existing in summer and winter.
Besides, infectious disease may occur in each season, so PKD patients should pay more attention in order to prevent infections and colds and so on. This can decrease the chance of damaging kidney.
The key of treating PKD is to block Renal Fibrosis, repair injured renal inherent cells and protect remained renal function. Micro-Chinese Medicine is suggested to treat Polycystic Kidney Disease. It has been improved by clinical practices that this treatment has a good effect on treating PKD and this treatment can treat PKD by blocking Renal Fibrosis, prolonging patients’ life greatly.
From clinical viewpoint, the hottest and coldest seasons are both unfavorable for patients’ illness condition. Hot weather is easy to cause various infections like urinary tract infection, gastrointestinal tract infection and upper respiratory tract infection and so on, all of which can speed up the development of PKD illness condition directly or indirectly. PKD patients, especially patients in third or fourth stage, usually have much lower immunity. They are easy to catch a cold, which can not only worsen PKD illness condition, but also affect blood pressure condition.
Specialists on Kidney Disease note that: as for PKD patients, the best treating timings are spring and autumn, which can reduce disadvantages existing in summer and winter.
Besides, infectious disease may occur in each season, so PKD patients should pay more attention in order to prevent infections and colds and so on. This can decrease the chance of damaging kidney.
The key of treating PKD is to block Renal Fibrosis, repair injured renal inherent cells and protect remained renal function. Micro-Chinese Medicine is suggested to treat Polycystic Kidney Disease. It has been improved by clinical practices that this treatment has a good effect on treating PKD and this treatment can treat PKD by blocking Renal Fibrosis, prolonging patients’ life greatly.
2016年9月19日星期一
How to Diagnose Polycystic Kidney Disease
Polycystic Kidney Disease is a kind of familial hereditary disease.
Sometimes, each family member has this disease. Early diagnosis is very
important to treat Polycystic Kidney Disease which always occurs with symptoms
of Haematuria, High Blood Pressure and abdominal masses, etc. But only through
these symptoms, we can not get an exact diagnosis of Polycystic Kidney Disease.
Instead, exact diagnosis should be made after normal examinations.
Ⅰ. Laboratory Examination:
Firstly, routine urine test: no abnormality can be found in early stage and microscopic Haematuria can be found in middle and late stages. Some patients may get Albuminuria, and White Blood Cells and pyocyte can be found if there is stone or infection at the same time.
Secondly, urine osmotic pressure declines in the early stage, which may be caused by less renal sensitivity of diuretic. With renal function aggravation, renal concentrating function is damaged and osmotic pressure declines further.
Thirdly, serum creatinine and urea nitrogen increases with worsening Renal Insufficiency and Renal Failure.
Ⅱ. Imaging Examination:
Firstly, CT examination has a correct rate of more than 90% on Polycystic Kidney Disease diagnosis. Through CT examination, cysts can be seen with obvious boundary to renal parenchyma and bilateral kidneys change their normal shape. Besides, complicated cysts in liver and spleen can also be found by CT examination.
Secondly, MRI is beneficial to define cyst fluid composition. When cyst internal bleeding happens, hemoglobin can be degraded and ferrous iron reduces to ferric iron which has paramagnetic characteristic, leading to abnormal signal.
Thirdly, X-Ray abdominal plain film shows enlarged kidney shape. IVP test is expressed by renal pelvis and renal calices malformation in strange spiderlike shape.
Fourthly, Type-B Ultrasonic examination is the first choice to diagnose Polycystic Kidney Disease presently. Through Type-B Ultrasonic, typical expression of cysts is no echo areas with various sizes in bilateral kidneys. Cyst wall is not clear, but with strong echo. Cysts are in round or oval shape. Complex masses can be found through Type-B Ultrasonic examination if this disease is complicated with cyst internal bleeding, stone and calcification, etc.
When Polycystic Kidney Disease develops into some certain degree, it is not difficult to make a clinical diagnosis based on irregular bilateral kidneys enlargement, various sizes of cysts in bilateral kidneys through Type-B Ultrasonic examination, CT and other imaging examinations, as well as patients family history.
Once patients are diagnosed as Polycystic Kidney Disease, they should accept treatment actively in order to delay illness condition developing and prevent Polycystic Kidney Disease developing into Renal Failure and Uremia.
Ⅰ. Laboratory Examination:
Firstly, routine urine test: no abnormality can be found in early stage and microscopic Haematuria can be found in middle and late stages. Some patients may get Albuminuria, and White Blood Cells and pyocyte can be found if there is stone or infection at the same time.
Secondly, urine osmotic pressure declines in the early stage, which may be caused by less renal sensitivity of diuretic. With renal function aggravation, renal concentrating function is damaged and osmotic pressure declines further.
Thirdly, serum creatinine and urea nitrogen increases with worsening Renal Insufficiency and Renal Failure.
Ⅱ. Imaging Examination:
Firstly, CT examination has a correct rate of more than 90% on Polycystic Kidney Disease diagnosis. Through CT examination, cysts can be seen with obvious boundary to renal parenchyma and bilateral kidneys change their normal shape. Besides, complicated cysts in liver and spleen can also be found by CT examination.
Secondly, MRI is beneficial to define cyst fluid composition. When cyst internal bleeding happens, hemoglobin can be degraded and ferrous iron reduces to ferric iron which has paramagnetic characteristic, leading to abnormal signal.
Thirdly, X-Ray abdominal plain film shows enlarged kidney shape. IVP test is expressed by renal pelvis and renal calices malformation in strange spiderlike shape.
Fourthly, Type-B Ultrasonic examination is the first choice to diagnose Polycystic Kidney Disease presently. Through Type-B Ultrasonic, typical expression of cysts is no echo areas with various sizes in bilateral kidneys. Cyst wall is not clear, but with strong echo. Cysts are in round or oval shape. Complex masses can be found through Type-B Ultrasonic examination if this disease is complicated with cyst internal bleeding, stone and calcification, etc.
When Polycystic Kidney Disease develops into some certain degree, it is not difficult to make a clinical diagnosis based on irregular bilateral kidneys enlargement, various sizes of cysts in bilateral kidneys through Type-B Ultrasonic examination, CT and other imaging examinations, as well as patients family history.
Once patients are diagnosed as Polycystic Kidney Disease, they should accept treatment actively in order to delay illness condition developing and prevent Polycystic Kidney Disease developing into Renal Failure and Uremia.
2016年9月16日星期五
Process of Polycystic Kidney Disease Developing into Uremia
It is a slow developing process from Polycystic Kidney Disease to Uremia.
Growing and increasing cysts are root cause of leading to Uremia. In the early
stage, there are very few cysts in kidney, and cyst number increases with
illness development. Finally, healthy kidney can be filled with massive cysts,
resulting in High Blood Pressure and renal functional abnormality. Then Uremia
occurs naturally.
There are five stages in the process of Polycystic Kidney Disease developing into Uremia:
StageⅠ. Polycystic Kidney Disease Occurring Stage:
Polycystic Kidney Disease is a kind of hereditary disease. Patients were born with smaller cysts which are difficult to be found. Generally, this disease can not be found before patients are 20 years old. If there is Polycystic Kidney Disease patient in one family, other family members should go to hospital for a check as early as possible in order to observe cysts growing condition in time. Besides, patients should care more about their daily life in this stage.
Stage Ⅱ. Growing Stage:
When patients are in the age range of 30 to 40 years old, cysts grow faster than the first stage. In this stage, close observation is necessary. Western Medicine has no effective way to treat this disease and holds the opinion that there is no need to treat the disease in this stage. Actually, patients still need active treatment in this stage with the purpose to stop or delay cysts growing through applying Chinese Medicine with strong function of activating blood and eliminating blood stasis. Through this way, patients’ life can be prolonged greatly. In a sense, this stage is the key stage for Micro-Chinese Medicine to delay cysts growth.
Stage Ⅲ. Cyst Swollen Stage:
After patients are 40 years old, cysts can have a further growth and enlargement. With cysts growing, more clinical symptoms, like waist pain, Albuminuria, Haematuria, High Blood Pressure, appear. As for treatment, this stage is a very important stage for the treatment of Chinese Medicine combined with Western Medicine to play its role in treating Polycystic Kidney Disease.
Stage Ⅳ. Cyst Rupture Stage:
If cysts grow continuously, cyst rupture happens under the action of some external factors. Once cyst rupture happens, patients should be sent to hospital for treatment as soon as possible in order to control infection, prevent Hematosepsis and acute renal function aggravation, which is beneficial to solve other symptoms.
StageⅤ. Uremia Stage:
Polycystic Kidney Disease is a kind of hereditary disease, which means that normal renal tissue is replaced by cysts with fluid inside. When these cysts grow bigger, they will lead to kidney functional abnormality, causing difficulty for kidney to play its normal role in excreting metabolism waste. With illness condition development, renal function is so damaged and Uremia happens. As for treatment of Uremia, the key is to block Renal Fibrosis.
From the above, we can see that it is a very slow process of Polycystic Kidney Disease developing into Uremia. Though Polycystic Kidney Disease can not be eliminate from its root, it can be controlled effectively if proper treatment can be taken to block Renal Fibrosis, which is helpful to prevent PKD developing into Uremia.
There are five stages in the process of Polycystic Kidney Disease developing into Uremia:
StageⅠ. Polycystic Kidney Disease Occurring Stage:
Polycystic Kidney Disease is a kind of hereditary disease. Patients were born with smaller cysts which are difficult to be found. Generally, this disease can not be found before patients are 20 years old. If there is Polycystic Kidney Disease patient in one family, other family members should go to hospital for a check as early as possible in order to observe cysts growing condition in time. Besides, patients should care more about their daily life in this stage.
Stage Ⅱ. Growing Stage:
When patients are in the age range of 30 to 40 years old, cysts grow faster than the first stage. In this stage, close observation is necessary. Western Medicine has no effective way to treat this disease and holds the opinion that there is no need to treat the disease in this stage. Actually, patients still need active treatment in this stage with the purpose to stop or delay cysts growing through applying Chinese Medicine with strong function of activating blood and eliminating blood stasis. Through this way, patients’ life can be prolonged greatly. In a sense, this stage is the key stage for Micro-Chinese Medicine to delay cysts growth.
Stage Ⅲ. Cyst Swollen Stage:
After patients are 40 years old, cysts can have a further growth and enlargement. With cysts growing, more clinical symptoms, like waist pain, Albuminuria, Haematuria, High Blood Pressure, appear. As for treatment, this stage is a very important stage for the treatment of Chinese Medicine combined with Western Medicine to play its role in treating Polycystic Kidney Disease.
Stage Ⅳ. Cyst Rupture Stage:
If cysts grow continuously, cyst rupture happens under the action of some external factors. Once cyst rupture happens, patients should be sent to hospital for treatment as soon as possible in order to control infection, prevent Hematosepsis and acute renal function aggravation, which is beneficial to solve other symptoms.
StageⅤ. Uremia Stage:
Polycystic Kidney Disease is a kind of hereditary disease, which means that normal renal tissue is replaced by cysts with fluid inside. When these cysts grow bigger, they will lead to kidney functional abnormality, causing difficulty for kidney to play its normal role in excreting metabolism waste. With illness condition development, renal function is so damaged and Uremia happens. As for treatment of Uremia, the key is to block Renal Fibrosis.
From the above, we can see that it is a very slow process of Polycystic Kidney Disease developing into Uremia. Though Polycystic Kidney Disease can not be eliminate from its root, it can be controlled effectively if proper treatment can be taken to block Renal Fibrosis, which is helpful to prevent PKD developing into Uremia.
2016年9月15日星期四
Effect on Blocking Renal Fibrosis by Micro-Chinese Medicine Osmotherapy
Talking about effects of Micro-Chinese Medicine on treating kinds of Kidney
Diseases, both short-term effects and long-term effects should be
considered.
Ⅰ. Short-term Clinical effects: Micro-Chinese Medicine plays its role in blocking Renal Fibrosis from four aspects: dilating blood vessel, anti-inflammation, anticoagulation and degrading Extracellular Matrix (ECM). Generally, three clinical manifestations can be observed in short term.
Firstly, once injured renal arteries at all levels are dilated, with the cooperation of other functions of Micro-Chinese Medicine Osmotherapy, such as anti-inflammation, anticoagulation, preventing thrombus and degradation, a series of short-term clinical manifestations appear. Patients have more urine amount with deepening colour and heavy smell. Patients’ urine become turbid and floccule like material can be found in urine, which is a show of gradually recovered renal ability of excreting toxin and more urine creatinine being excreted out of body.
Secondly, improved whole body microcirculation can promote whole body blood circulation and reduce the condition of renal ischemia and anoxia as well as poisoning symptoms. Under such circumstances, whole body tiredness and skin itch can be relieved. Patients begin to sweat and patients’ feeling of minding cold weather will reduce or disappear. Besides, due to improved circulation condition, patients will have a ruddy appearance of their hands and face. What's more, long-term High Blood Pressure will be reduced to healthy normal gradually.
Thirdly, after the treatment of Micro-Chinese Medicine Osmotherapy, mucosa edema of gastrointestinal tract disappears gradually, which can improve local microcirculation and increase digestive juice secretion. For this reason, patients can have an increased appetite and symptoms of nausea and vomiting disappear, with lessening nitrogen smell in mouth.
Ⅱ. Long-term effect:
Firstly, Albuminuria disappearance is one of the long-term effects of Micro-Chinese Medicine in blocking Renal Fibrosis. Through effective repair of injured renal inherent cells, especially remained epithelial cells of glomerulus, glomerular selective filtrating function can also be recovered. Once selective filtrating function recovers, glomerular function of preventing protein leakage can return. But the process of repairing epithelial cells of glomerular is a long course with certain objective regulation, so Albuminuria disappearance belongs to the long-term effects of Micro-Chinese Medicine Osmotherapy in blocking Renal Fibrosis.
Secondly, Haematuria disappearance is also one of long-term effects. Aiming at treating Haematuria, Micro-Chinese Medicine Osmotherapy also starts with blocking Renal Fibrosis, and then recovers injured renal inherent cells as well as activates metabolic function and selective filtrating function of inherent cells. Only after effective repair of barrier function, kinds of inherent cells can get their function of preventing Rend Blood Cells leakage back. Then Haematuria disappears.
Thirdly, reduced serum creatinine is one of long-term effects. Due to inherent cells injury, their function of excreting toxin is also damaged. Excessive metabolic wastes like creatinine, urea nitrogen and uric acid can not be excreted out of human body in time, which causes serum creatinine increase in body.
There is still one point should be noted that no matter what treatment patients choose, the repairing course is some long. During this course, patients should have a healthy mentality and cooperate with doctors actively as well as be cautious about any inducement that can speed up illness development.
Ⅰ. Short-term Clinical effects: Micro-Chinese Medicine plays its role in blocking Renal Fibrosis from four aspects: dilating blood vessel, anti-inflammation, anticoagulation and degrading Extracellular Matrix (ECM). Generally, three clinical manifestations can be observed in short term.
Firstly, once injured renal arteries at all levels are dilated, with the cooperation of other functions of Micro-Chinese Medicine Osmotherapy, such as anti-inflammation, anticoagulation, preventing thrombus and degradation, a series of short-term clinical manifestations appear. Patients have more urine amount with deepening colour and heavy smell. Patients’ urine become turbid and floccule like material can be found in urine, which is a show of gradually recovered renal ability of excreting toxin and more urine creatinine being excreted out of body.
Secondly, improved whole body microcirculation can promote whole body blood circulation and reduce the condition of renal ischemia and anoxia as well as poisoning symptoms. Under such circumstances, whole body tiredness and skin itch can be relieved. Patients begin to sweat and patients’ feeling of minding cold weather will reduce or disappear. Besides, due to improved circulation condition, patients will have a ruddy appearance of their hands and face. What's more, long-term High Blood Pressure will be reduced to healthy normal gradually.
Thirdly, after the treatment of Micro-Chinese Medicine Osmotherapy, mucosa edema of gastrointestinal tract disappears gradually, which can improve local microcirculation and increase digestive juice secretion. For this reason, patients can have an increased appetite and symptoms of nausea and vomiting disappear, with lessening nitrogen smell in mouth.
Ⅱ. Long-term effect:
Firstly, Albuminuria disappearance is one of the long-term effects of Micro-Chinese Medicine in blocking Renal Fibrosis. Through effective repair of injured renal inherent cells, especially remained epithelial cells of glomerulus, glomerular selective filtrating function can also be recovered. Once selective filtrating function recovers, glomerular function of preventing protein leakage can return. But the process of repairing epithelial cells of glomerular is a long course with certain objective regulation, so Albuminuria disappearance belongs to the long-term effects of Micro-Chinese Medicine Osmotherapy in blocking Renal Fibrosis.
Secondly, Haematuria disappearance is also one of long-term effects. Aiming at treating Haematuria, Micro-Chinese Medicine Osmotherapy also starts with blocking Renal Fibrosis, and then recovers injured renal inherent cells as well as activates metabolic function and selective filtrating function of inherent cells. Only after effective repair of barrier function, kinds of inherent cells can get their function of preventing Rend Blood Cells leakage back. Then Haematuria disappears.
Thirdly, reduced serum creatinine is one of long-term effects. Due to inherent cells injury, their function of excreting toxin is also damaged. Excessive metabolic wastes like creatinine, urea nitrogen and uric acid can not be excreted out of human body in time, which causes serum creatinine increase in body.
There is still one point should be noted that no matter what treatment patients choose, the repairing course is some long. During this course, patients should have a healthy mentality and cooperate with doctors actively as well as be cautious about any inducement that can speed up illness development.
2016年9月14日星期三
Case Analysis of Polycystic Kidney Disease in Shijiazhuang Kidney Disease Hospital
Patient: Li Yushan, 45 years old, Hebei Province
Diagnosed: Polycystic Kidney Disease
When patients came to our hospital: he had really bad appetite, mental condition and sleep quality. He also had distending pain on his bilateral kidney region. Patient did not suffer from Edema, but swelling block can be seen on abdominal region when patient is lying flat, and two swelling masses can be touched on bilateral sides of abdomen with unsmooth surface. Pressing pain can be felt.
Test result when patient came to our hospital: Blood Pressure, 170/100mmHg; Heart Rate: 80/min; hemachrome, 10g.
Through Type-B Ultrasonic examination: left kidney, 20.0×10.0×8.0cm; right kidney, 22.0×12.0×8.0cm; largest cyst in left kidney, 5.0×4.5cm, largest cyst in right kidney, 5.6×4.8cm.
Through ECT examination: multiple diffusing damage on bilateral kidney; low blood perfusion of bilateral kidney; decreased glomerular filtrating rate of bilateral kidney, left kidney, 32ml/min, right kidney 30ml/min; slow excretion of bilateral upper urinary tract.
Treatment: according to patient’s illness condition, doctors give him Micro-Chinese Medicine Osmotherapy. After treatment, patient has an improved mental condition, appetite and sleep quality. Distending pain disappears gradually.
Test result after treatment: Blood Pressure: 130/80mmHg, no hypotensor was taken; hemachrome, 12g; Serum creatinine, 98μmol/L; blood urea nitrogen, 6.8mmol/L; blood uric acid, 402.0μmol/L; Blood potassium, 4.48mmol/L.
Through Type-B Ultrasonic examination: left kidney, 15.0×5.0×4.0cm; right kidney, 16.0×7.0×4.0cm; largest cyst in left cyst, 2.0×2.0cm; largest cyst in right kidney, 2.6×2.0cm.
Through ECT examination: filtrating rate of left kidney, 58ml/min; filtrating rate of right kidney, 52ml/min; bilateral upper urinary tract is smoothly.
Diagnosed: Polycystic Kidney Disease
When patients came to our hospital: he had really bad appetite, mental condition and sleep quality. He also had distending pain on his bilateral kidney region. Patient did not suffer from Edema, but swelling block can be seen on abdominal region when patient is lying flat, and two swelling masses can be touched on bilateral sides of abdomen with unsmooth surface. Pressing pain can be felt.
Test result when patient came to our hospital: Blood Pressure, 170/100mmHg; Heart Rate: 80/min; hemachrome, 10g.
Through Type-B Ultrasonic examination: left kidney, 20.0×10.0×8.0cm; right kidney, 22.0×12.0×8.0cm; largest cyst in left kidney, 5.0×4.5cm, largest cyst in right kidney, 5.6×4.8cm.
Through ECT examination: multiple diffusing damage on bilateral kidney; low blood perfusion of bilateral kidney; decreased glomerular filtrating rate of bilateral kidney, left kidney, 32ml/min, right kidney 30ml/min; slow excretion of bilateral upper urinary tract.
Treatment: according to patient’s illness condition, doctors give him Micro-Chinese Medicine Osmotherapy. After treatment, patient has an improved mental condition, appetite and sleep quality. Distending pain disappears gradually.
Test result after treatment: Blood Pressure: 130/80mmHg, no hypotensor was taken; hemachrome, 12g; Serum creatinine, 98μmol/L; blood urea nitrogen, 6.8mmol/L; blood uric acid, 402.0μmol/L; Blood potassium, 4.48mmol/L.
Through Type-B Ultrasonic examination: left kidney, 15.0×5.0×4.0cm; right kidney, 16.0×7.0×4.0cm; largest cyst in left cyst, 2.0×2.0cm; largest cyst in right kidney, 2.6×2.0cm.
Through ECT examination: filtrating rate of left kidney, 58ml/min; filtrating rate of right kidney, 52ml/min; bilateral upper urinary tract is smoothly.
How to Prevent Polycystic Kidney Disease (PKD) Aggravation
Polycystic Kidney Disease patients should accept effective treatment actively
in order to prevent illness condition aggravating. But only medicinal treatment
is not enough. In daily life, patients should prevent cold and infection
actively with the purpose of preventing Polycystic Kidney Disease developing
into Renal Failure and Uremia. Generally, Polycystic Kidney Disease patients can
start with the following aspects.
Firstly, preventing cold: Polycystic Kidney Disease is a kind of whole life hereditary disease. No matter how much care family members give to patients, the fact that cysts keep growing can not be changed. If patients catch colds in this period, their renal injury will be worsened, which can speed up the developing of renal function injury.
Secondly, prevent trauma: with cysts of Polycystic Kidney Disease growing, these cysts can increase cyst internal pressure continuously, enlarging patients’ bilateral kidneys. At this moment, any tiny trauma like sprain, injury or fall wound may increase abdomen internal pressure or these trauma may act on cysts directly, which may cause cyst rupture and bleeding, inducing infection easily.
Thirdly, control blood pressure: most PKD patients get Hypertension before renal function is damaged. Hypertension can speed up renal injury. Besides, Hypertension can also damage heart blood vessel and cerebral blood vessel, causing encephalic dngioma and other complications. For this reason, controlling blood pressure effectively has a significant role in delaying renal function aggravation and preventing complications.
Fourthly, scientific diet: proper daily diet is very important to control renal function aggravation. Diet with low salt, 2 to 3g per day, is suitable. Patients should eat less food with potassium, phosphor and low protein and low fat. Foods with more vegetable coarse fiber should be taken more.
The key of treating Polycystic Kidney Disease is to block Renal Fibrosis, repair injured renal inherent cells and control cyst growing, which can prevent Polycystic Kidney Disease developing into Renal Failure and Uremia
Firstly, preventing cold: Polycystic Kidney Disease is a kind of whole life hereditary disease. No matter how much care family members give to patients, the fact that cysts keep growing can not be changed. If patients catch colds in this period, their renal injury will be worsened, which can speed up the developing of renal function injury.
Secondly, prevent trauma: with cysts of Polycystic Kidney Disease growing, these cysts can increase cyst internal pressure continuously, enlarging patients’ bilateral kidneys. At this moment, any tiny trauma like sprain, injury or fall wound may increase abdomen internal pressure or these trauma may act on cysts directly, which may cause cyst rupture and bleeding, inducing infection easily.
Thirdly, control blood pressure: most PKD patients get Hypertension before renal function is damaged. Hypertension can speed up renal injury. Besides, Hypertension can also damage heart blood vessel and cerebral blood vessel, causing encephalic dngioma and other complications. For this reason, controlling blood pressure effectively has a significant role in delaying renal function aggravation and preventing complications.
Fourthly, scientific diet: proper daily diet is very important to control renal function aggravation. Diet with low salt, 2 to 3g per day, is suitable. Patients should eat less food with potassium, phosphor and low protein and low fat. Foods with more vegetable coarse fiber should be taken more.
The key of treating Polycystic Kidney Disease is to block Renal Fibrosis, repair injured renal inherent cells and control cyst growing, which can prevent Polycystic Kidney Disease developing into Renal Failure and Uremia
2016年9月7日星期三
How Does Immunotherapy Treat Polycystic Kidney Disease
With medicine technology development, Immunotherapy has gained great
achievement on treating Polycystic Kidney Disease (PKD). Polycystic Kidney is a
kind of genetic disease, following the regulation of autosomal dominant
inheritance. Both male and female have equal incidence. In the early stage, when
cysts are still small, seldom obvious symptoms can be found. But with cysts
growing and increasing, they will compress surrounding healthy tissue greatly.
Then symptoms appear. Waist pain usually happens firstly, and Haematuria or
Nephropyelitis may appear occasionally. But most patients usually neglect these
symptoms because these symptoms are usually not serious. When cysts replace more
and more renal tissue and pressure become larger and larger, End Stage Renal
Failure happens.
Immunotherapy are transfused into patients' body through vein. After Immunotherapy entering into kidney lesions, they can differentiate into necessary cells that tissues need and repair injured renal inherent cells. Basically, Immunotherapy treat Polycystic Kidney Disease starting with shrinking cysts in order to reduce pressure on surrounding tissue and recover injured tissue function, trying to get maximum effect with minimum damage. Eliminating or controlling cysts in early stage can prevent Polycystic Kidney Disease developing into Renal Insufficiency and Renal Failure, or even Uremia greatly.
Besides, by applying Immunotherapy to treat Polycystic Kidney Disease, after healing, this disease seldom relapses. What's more, Immunotherapy has no side effect. So it brings no damage to patients' body. Polycystic Kidney Disease patients should take active treatment before renal function decline with principle of early finding and early treatment.
Immunotherapy are transfused into patients' body through vein. After Immunotherapy entering into kidney lesions, they can differentiate into necessary cells that tissues need and repair injured renal inherent cells. Basically, Immunotherapy treat Polycystic Kidney Disease starting with shrinking cysts in order to reduce pressure on surrounding tissue and recover injured tissue function, trying to get maximum effect with minimum damage. Eliminating or controlling cysts in early stage can prevent Polycystic Kidney Disease developing into Renal Insufficiency and Renal Failure, or even Uremia greatly.
Besides, by applying Immunotherapy to treat Polycystic Kidney Disease, after healing, this disease seldom relapses. What's more, Immunotherapy has no side effect. So it brings no damage to patients' body. Polycystic Kidney Disease patients should take active treatment before renal function decline with principle of early finding and early treatment.
Five Elements in Chinese Medicine
In Chinese Medicine, the concept of Five Elements refers to the activity of
metal, wood, water, fire and earth. It is used to explain the abstract concept
of relationship among things or events, with wide connotation. These five
elements do not refer to these five specific elements themselves.
Wood: elements that have the function or nature of growing, ascending and dredging or easiness belong to wood element.
Fire: everything that has the function or nature of heat or rising belong to fire element.
Earth: elements with the function of bearing, nursing and receiving belong to earth element.
Metal: elements with function of clearing, descent, or gathering belong to metal element.
Water: elements with the characteristics of cold and cool, moistening and moving downward are water elements.
The theory of five elements explains the mutual relation among objects by applying the concept of mutually reinforce and restrict each other. This theory considers that nothing is isolated and still. Instead, they maintain a balance in movement of reinforcement and restriction.
In Chinese Medicine, based on different characteristic s of these five elements, this theory is mainly used to analyze the nature of five elements and mutual relation of organic Zang-Fu (internal organs), channels and physical function.
Besides, it is used to explain the mutual influence of Zang-Fu, channels and physical function under the pathological condition.
Wood: elements that have the function or nature of growing, ascending and dredging or easiness belong to wood element.
Fire: everything that has the function or nature of heat or rising belong to fire element.
Earth: elements with the function of bearing, nursing and receiving belong to earth element.
Metal: elements with function of clearing, descent, or gathering belong to metal element.
Water: elements with the characteristics of cold and cool, moistening and moving downward are water elements.
The theory of five elements explains the mutual relation among objects by applying the concept of mutually reinforce and restrict each other. This theory considers that nothing is isolated and still. Instead, they maintain a balance in movement of reinforcement and restriction.
In Chinese Medicine, based on different characteristic s of these five elements, this theory is mainly used to analyze the nature of five elements and mutual relation of organic Zang-Fu (internal organs), channels and physical function.
Besides, it is used to explain the mutual influence of Zang-Fu, channels and physical function under the pathological condition.
2016年9月2日星期五
Cautions for Polycystic Kidney Disease Patients
What should Polycystic Kidney Disease patients pay attention to? According to
general regulation of PKD development, Polycystic Kidney Disease usually happens
when patients are 30 to 50 years old. However, the developing speed also has
some relationship with individual body condition and daily life style. So what
should patients pay attention to in the process of treating Polycystic Kidney
Disease (PKD)?
Firstly, PKD patients should prevent cold actively. If patients catch a cold, especially repeated cold, more serious immune damage to renal injury of Polycystic Kidney Disease can be caused, which can worsen illness condition further. Though Micro-Chinese Medicine can improve patients’ immunity, if patients do not care seriously, immune damage caused by repeated cold will limit active substances of Micro-Chinese Medicine to play their function.
Secondly, patients should avoid tiredness, which includes physical tiredness and brain tiredness. Brain tiredness can affect the though and command function of brain. For example, if central command system is out of order, functions of each internal organ can be influenced greatly, causing inconsonance of each organ, which can lead to other diseases and worsen illness condition. As for physical tiredness, more metabolic toxin will be produced after physical activity, but injured kidney can not excrete these toxins out of body, which worsens renal function injury.
Thirdly, patient should prevent trauma. With cysts growing, cyst internal pressure increases at the same time, which enlarges patients’ bilateral kidneys and increase abdomen internal pressure. Any external pressure on abdomen may have the possibility to cause cyst rupture and bleeding, inducing infection. So patients should pay enough attention on preventing trauma in order to protect their kidneys.
Micro-Chinese Medicine Osmotherapy is suggested to treat Polycystic Kidney Disease. This treatment can reduce cyst fluid secretion, decrease pressure on glomerulus, renal tubule and kidney blood vessel. Besides, this treatment can also improve renal blood circulation and relieve the condition of local kidney anoxia, proving a favorable environment for injured renal inherent cells to recover. It has been proved that this treatment has a good clinical effect on treating Polycystic Kidney Disease.
Firstly, PKD patients should prevent cold actively. If patients catch a cold, especially repeated cold, more serious immune damage to renal injury of Polycystic Kidney Disease can be caused, which can worsen illness condition further. Though Micro-Chinese Medicine can improve patients’ immunity, if patients do not care seriously, immune damage caused by repeated cold will limit active substances of Micro-Chinese Medicine to play their function.
Secondly, patients should avoid tiredness, which includes physical tiredness and brain tiredness. Brain tiredness can affect the though and command function of brain. For example, if central command system is out of order, functions of each internal organ can be influenced greatly, causing inconsonance of each organ, which can lead to other diseases and worsen illness condition. As for physical tiredness, more metabolic toxin will be produced after physical activity, but injured kidney can not excrete these toxins out of body, which worsens renal function injury.
Thirdly, patient should prevent trauma. With cysts growing, cyst internal pressure increases at the same time, which enlarges patients’ bilateral kidneys and increase abdomen internal pressure. Any external pressure on abdomen may have the possibility to cause cyst rupture and bleeding, inducing infection. So patients should pay enough attention on preventing trauma in order to protect their kidneys.
Micro-Chinese Medicine Osmotherapy is suggested to treat Polycystic Kidney Disease. This treatment can reduce cyst fluid secretion, decrease pressure on glomerulus, renal tubule and kidney blood vessel. Besides, this treatment can also improve renal blood circulation and relieve the condition of local kidney anoxia, proving a favorable environment for injured renal inherent cells to recover. It has been proved that this treatment has a good clinical effect on treating Polycystic Kidney Disease.
Causes of Urinary Occult Blood
Urinary occult blood is just a title which means latent bleeding in urine
tested out by routine urine test. During routine urine test, there is an item of
Red Blood Cells. If the number of Red Blood Cells increases, even tiny number
can be called urinary occult blood.
Urinary occult blood test showing positive result can only means that there are Red Blood Cells in urine. These Red Blood Cells are not real complete Red Blood Cells with form through microscopic. Instead, these are composition of Red Blood Cell tested out by computer. Normally, Red Blood Cells of body are broken down continuously and their compositions are excreted out of body with urine. Therefore, even healthy person may get a positive result in a test. Generally, through high magnification, 0 to 1 Red Blood Cell is normal. When Red Blood Cells are more than 3/Hp under microscope, it can be diagnosed as Haematuria.
Urinary occult blood and Haematuria: positive urinary occult blood result just means Red Blood Cell in urine tested out by examination, but not gross Haematuria. Haematuria can be divided into gross Haematuria, total Haematuria and positive urinary occult blood.
Normally, urinary occult blood is caused the following three reasons: inflammation, stones and tumor. As for inflammation, besides Haematuria, patients suffering from Glomerulonephritis, nephropyelitis and cystitis and so on can also be tested out urinary occult blood through urine test. As for stones, no matter what place stone stay, kidney, ureter or urinary bladder, urinary occult blood may happen. Other conditions like menstrual period or constipation can also cause urinary occult blood. The last one, tumor, like benign or malignant tumor of kidney, urinary bladder or ureter, can cause urinary occult blood.
Urinary occult blood test showing positive result can only means that there are Red Blood Cells in urine. These Red Blood Cells are not real complete Red Blood Cells with form through microscopic. Instead, these are composition of Red Blood Cell tested out by computer. Normally, Red Blood Cells of body are broken down continuously and their compositions are excreted out of body with urine. Therefore, even healthy person may get a positive result in a test. Generally, through high magnification, 0 to 1 Red Blood Cell is normal. When Red Blood Cells are more than 3/Hp under microscope, it can be diagnosed as Haematuria.
Urinary occult blood and Haematuria: positive urinary occult blood result just means Red Blood Cell in urine tested out by examination, but not gross Haematuria. Haematuria can be divided into gross Haematuria, total Haematuria and positive urinary occult blood.
Normally, urinary occult blood is caused the following three reasons: inflammation, stones and tumor. As for inflammation, besides Haematuria, patients suffering from Glomerulonephritis, nephropyelitis and cystitis and so on can also be tested out urinary occult blood through urine test. As for stones, no matter what place stone stay, kidney, ureter or urinary bladder, urinary occult blood may happen. Other conditions like menstrual period or constipation can also cause urinary occult blood. The last one, tumor, like benign or malignant tumor of kidney, urinary bladder or ureter, can cause urinary occult blood.
2016年9月1日星期四
Attach Importance to Damage of Polycystic Kidney Disease (PKD)
Polycystic Kidney Disease means that countless cysts in various sizes grow in
the surface of kidneys, isolated with renal pelvis. Cysts are growing with age.
For this reason, renal function declines with growing cysts.
Clinically, autosomal dominant inheritance is common among Polycystic Kidney Disease cases, with main feature of abnormal proliferation of renal tubular epithelial cells. When epithelial cells of renal tubule have a phenotype change, turning into cyst epithelial cells, they get secretion function, which can increase cyst fluid secretion. But there is no normal way to excrete these fluids. With aging, a large amount of cyst fluid deposit in body, enlarging cyst size as well as increasing cyst internal pressure and cystic surface tensility. At this moment, some sensitive patients may feel discomfort on waist. When there is a local infection, patients get a painful feeling. With cysts growing bigger, healthy renal structure will be replaced by cysts, causing renal function decline. Meanwhile, High Blood Pressure, abnormality in routine urine test and renal function tests appear as clinical symptoms.
As for patients suffering from early stage Polycystic Kidney Disease (PKD), operations can be considered to remove larger cysts in order to reduce damage to kidneys. However, operation can not treat these cysts completely. Instead, this disease is easy to relapse after operation. According to this problem, Micro-Chinese Medicine Osmotherapy was developed by China Shijiazhuang Kidney Disease Hospital. This treatment can treat Polycystic Kidney Disease (PKD) starting with inhibiting cysts growing, which means eliminating activity of cystic epithelial cells and making these cells lose secreting activity. Once cyst fluid stops being secreted, cysts can stay in present stage and keep present size. But cysts have already formed, so proper medicine should be taken to increase permeability of cystic surface blood circulation and reabsorb cyst fluid. Finally, these cysts can be excreted out of body with urine after metabolism. From the above, it can be obviously found that Micro-Chinese Medicine can treat Polycystic Kidney Disease (PKD) radically, and after healing, this disease seldom relapses.
Some patients go to hospital for treatment when their symptoms are worsened seriously. For this reason, their disease has developed into middle or late stage usually, or even cicatricial phase of Renal Fibrosis. at this moment, they always have bad treating effect and really expensive cost, which burdens their family and themselves heavily. So Polycystic Kidney Disease (PKD) should have a proper recognition on Polycystic Kidney Disease (PKD), accepting body check regularly with the purpose of early detection and early treatment.
Clinically, autosomal dominant inheritance is common among Polycystic Kidney Disease cases, with main feature of abnormal proliferation of renal tubular epithelial cells. When epithelial cells of renal tubule have a phenotype change, turning into cyst epithelial cells, they get secretion function, which can increase cyst fluid secretion. But there is no normal way to excrete these fluids. With aging, a large amount of cyst fluid deposit in body, enlarging cyst size as well as increasing cyst internal pressure and cystic surface tensility. At this moment, some sensitive patients may feel discomfort on waist. When there is a local infection, patients get a painful feeling. With cysts growing bigger, healthy renal structure will be replaced by cysts, causing renal function decline. Meanwhile, High Blood Pressure, abnormality in routine urine test and renal function tests appear as clinical symptoms.
As for patients suffering from early stage Polycystic Kidney Disease (PKD), operations can be considered to remove larger cysts in order to reduce damage to kidneys. However, operation can not treat these cysts completely. Instead, this disease is easy to relapse after operation. According to this problem, Micro-Chinese Medicine Osmotherapy was developed by China Shijiazhuang Kidney Disease Hospital. This treatment can treat Polycystic Kidney Disease (PKD) starting with inhibiting cysts growing, which means eliminating activity of cystic epithelial cells and making these cells lose secreting activity. Once cyst fluid stops being secreted, cysts can stay in present stage and keep present size. But cysts have already formed, so proper medicine should be taken to increase permeability of cystic surface blood circulation and reabsorb cyst fluid. Finally, these cysts can be excreted out of body with urine after metabolism. From the above, it can be obviously found that Micro-Chinese Medicine can treat Polycystic Kidney Disease (PKD) radically, and after healing, this disease seldom relapses.
Some patients go to hospital for treatment when their symptoms are worsened seriously. For this reason, their disease has developed into middle or late stage usually, or even cicatricial phase of Renal Fibrosis. at this moment, they always have bad treating effect and really expensive cost, which burdens their family and themselves heavily. So Polycystic Kidney Disease (PKD) should have a proper recognition on Polycystic Kidney Disease (PKD), accepting body check regularly with the purpose of early detection and early treatment.
2016年8月31日星期三
Nine Killers impair Your Kidney Function
To prevent senilism, modern people need to do more exercises and nourish our
body in time to improve renal insufficient and senile symptoms. Excluding those
feeble patients, people should tonify kidney with a mild measure according to
seasons, body condition and climate. And it is better to follow doctor’s
instruction.
According to western medicine, kidney is an important organ to secrete urine, discharge waste and toxin. It can regulate electrolytic concentration in human body, and sustain acid-base equilibrium. With the aggravation of renal injure, Renal Secretion and regulation function will decline. When kidneys are damaged seriously, Uremia occurs, which threaten patient’s life.
With age growing, kidney function declines gradually. While in daily life, some bad habits or behaviors also can injure renal function.
For protect people kidney, people should be cautious about following points:
1. Abusing Chinese herbal medicine.
In recent years, it is found in Clinical practices that some Chinese herbal medicine, including Chinese patent medicine, can cause renal damage. Such medicines include caulis aristolochiae manshuriensis, thunder god vine, semen pharbitidis, cocklebur, poppy capsule, birthwort root, aristolochia fangchi etc. Among them, thunder god vine damage kidney most seriously, and caulis aristolochiae manshuriensis follows. The reason why caulis aristolochiae manshuriensis damage kidney is a kind of nephrotoxic material, aristolochic acid.
2. Abusing analgesic
Long term application or large dosage of anti-inflammation and analgesic medicine, like painkiller, indomethacin, paracetamol and aspirin etc, easily damage kidney. Renal damage manifested by fatigue, inappetence, frequent micturition, urgent urination, odyuria and even blood urine and sterile pyuria, accompanying with symptoms like arthralgia etc. Some times, it can directly cause Acute Nephritis or Glomerulus Necrosis and other kidney syndromes, Even Renal Failure, which threaten patient’s life .
3. Holding back urine frequently.
People usually hold back urine when they are busy for work. Bacteria are prone to propagate if urine stays in bladder for long. Bacteria can back to bladder through ureters, which causes urinary tract infection and Pyelonephritis. Once the repetition occurs, Chronic infection will happen and can not be cured easily. Patients have pain on back, frequent urination and urgent urination etc, or even Acute Uremia.
4. Drinking less water
Urine volume will decrease if people drink less water, and concentration of waste and toxin carried in blood will increase. Kidney Stone and Hydronephrosis and other common clinical symptoms have close relations with drinking less water. Drinking more water can dilute urine, protect kidney and is helpful to discharge waste and toxins.
5. Engorgement
Nowadays, people have more chance to dine together and take excessive delicious food which will be finally metabolized into wastes, like uric-acid and urea nitrogen etc. And these wastes are excreted out of body by kidney, so excessive diet will burden kidney.
6. Drinking beverage excessively
Excessive intake of soft drink and sport beverage can damage kidney indirectly. Because Ph value in human body is 7.2, however, these drinks are usually acid and Ph value in human body changes dramatically after drinking beverages. Kidney is the main organ to regulate acid-base equilibrium in human body. Excessive drinking soft and sport beverages for long can add kidney’s burden and increase the probability of kidney damage.
7. Eating floppy bread
There is an additive of potassium bromate in bread and cookie, and this additive can provide toasted food with necessary gluten intensity and flexibility which smell a mellow flavor. However, excessive intake of this additive can damage central nervous system, blood and kidney. Potassium bromate, as a food additive, has been listed as a carcinogen by international cancer research institute.
8. Too salty diet
Some snacks contain high salt, for example, fried chips, instant noodles, people will intake excess salt unconsciously by eating them, which can cause blood pressure increase, blood flow volume in kidney can not be sustained then kidney disease occurs.
9. Drink strong tea after liquoring
Some people think drinking strong tea after liquoring can relieve alcohol, actually, this is not effective and can damage kidney. Theophylline in tea can affect kidney rapidly, and exploit its diuresis function. At that moment, Alcohol has not been decomposed yet when they are secreted from kidney, which makes kidney stimulated by massive ethanol and renal function gets damaged.
According to western medicine, kidney is an important organ to secrete urine, discharge waste and toxin. It can regulate electrolytic concentration in human body, and sustain acid-base equilibrium. With the aggravation of renal injure, Renal Secretion and regulation function will decline. When kidneys are damaged seriously, Uremia occurs, which threaten patient’s life.
With age growing, kidney function declines gradually. While in daily life, some bad habits or behaviors also can injure renal function.
For protect people kidney, people should be cautious about following points:
1. Abusing Chinese herbal medicine.
In recent years, it is found in Clinical practices that some Chinese herbal medicine, including Chinese patent medicine, can cause renal damage. Such medicines include caulis aristolochiae manshuriensis, thunder god vine, semen pharbitidis, cocklebur, poppy capsule, birthwort root, aristolochia fangchi etc. Among them, thunder god vine damage kidney most seriously, and caulis aristolochiae manshuriensis follows. The reason why caulis aristolochiae manshuriensis damage kidney is a kind of nephrotoxic material, aristolochic acid.
2. Abusing analgesic
Long term application or large dosage of anti-inflammation and analgesic medicine, like painkiller, indomethacin, paracetamol and aspirin etc, easily damage kidney. Renal damage manifested by fatigue, inappetence, frequent micturition, urgent urination, odyuria and even blood urine and sterile pyuria, accompanying with symptoms like arthralgia etc. Some times, it can directly cause Acute Nephritis or Glomerulus Necrosis and other kidney syndromes, Even Renal Failure, which threaten patient’s life .
3. Holding back urine frequently.
People usually hold back urine when they are busy for work. Bacteria are prone to propagate if urine stays in bladder for long. Bacteria can back to bladder through ureters, which causes urinary tract infection and Pyelonephritis. Once the repetition occurs, Chronic infection will happen and can not be cured easily. Patients have pain on back, frequent urination and urgent urination etc, or even Acute Uremia.
4. Drinking less water
Urine volume will decrease if people drink less water, and concentration of waste and toxin carried in blood will increase. Kidney Stone and Hydronephrosis and other common clinical symptoms have close relations with drinking less water. Drinking more water can dilute urine, protect kidney and is helpful to discharge waste and toxins.
5. Engorgement
Nowadays, people have more chance to dine together and take excessive delicious food which will be finally metabolized into wastes, like uric-acid and urea nitrogen etc. And these wastes are excreted out of body by kidney, so excessive diet will burden kidney.
6. Drinking beverage excessively
Excessive intake of soft drink and sport beverage can damage kidney indirectly. Because Ph value in human body is 7.2, however, these drinks are usually acid and Ph value in human body changes dramatically after drinking beverages. Kidney is the main organ to regulate acid-base equilibrium in human body. Excessive drinking soft and sport beverages for long can add kidney’s burden and increase the probability of kidney damage.
7. Eating floppy bread
There is an additive of potassium bromate in bread and cookie, and this additive can provide toasted food with necessary gluten intensity and flexibility which smell a mellow flavor. However, excessive intake of this additive can damage central nervous system, blood and kidney. Potassium bromate, as a food additive, has been listed as a carcinogen by international cancer research institute.
8. Too salty diet
Some snacks contain high salt, for example, fried chips, instant noodles, people will intake excess salt unconsciously by eating them, which can cause blood pressure increase, blood flow volume in kidney can not be sustained then kidney disease occurs.
9. Drink strong tea after liquoring
Some people think drinking strong tea after liquoring can relieve alcohol, actually, this is not effective and can damage kidney. Theophylline in tea can affect kidney rapidly, and exploit its diuresis function. At that moment, Alcohol has not been decomposed yet when they are secreted from kidney, which makes kidney stimulated by massive ethanol and renal function gets damaged.
2016年8月30日星期二
Characteristic Treatment of Polycystic Kidney Disease (PKD)
Polycystic Kidney Disease (PKD) is a kind of hereditary Kidney Disease. Cysts
with various size form in unilateral or bilateral kidneys, growing with age.
When these cysts grow and increase to a certain degree, they begin to compress
kidneys, which can start the process of renal fibrosis and lead to renal
injury.
Due to the strong compensatory ability, kidney can operate normally in the early stage of Kidney Disease. For this reason, many Polycystic Kidney Disease (PKD) patients seldom have obvious symptoms in early stage, which is also the reason why the disease is always neglected by most patients. Therefore, when patients are tested out this disease, most of their kidneys have been already injured seriously.
China Shijiazhuang Kidney Disease Hospital has developed a distinctive treatment, Micro-Chinese Medicine Osmotherapy combined with Immunotherapy, to treat Polycystic Kidney Disease (PKD). It has been proved by clinical practice that this treatment has an excellent effect on treating Polycystic Kidney Disease (PKD) indeed.
Micro-Chinese Medicine Osmotherapy is developed on the basis of Traditional Chinese Medicine. It has solved the problems of less effective absorption and low effect process in Traditional Chinese Medicine. Micronized Chinese Medicine is so tiny that it can permeate into renal lesions by an external application on kidney region on patients’ back. After entering into patients’ body, Micro-Chinese Medicine can shrink existing cysts, reduce cyst fluid secretion and block Renal Fibrosis by improving kidney blood circulation and inhibiting activity of epithelial cells on cyst wall, which can repair injured kidney radically. Though Micro-Chinese Medicine can repair kidney effectively, it can not create new healthy nephron. Therefore, our hospital adopts Immunotherapy to cover this shortage.
Immunotherapy can differentiate into necessary cells that injured tissue needs and repair injured kidney at the same time, so as to get maximum effect with minimum injury. This is in accordance with Micro-Chinese Medicine Osmotherapy.
Besides the advantages of Micro-Chinese Medicine Osmotherapy mentioned above, another important point should be mentioned is that some compositions of Micro-Chinese Medicine Osmotherapy can play a guiding role after Immunotherapy are transfused into patients’ body, which can lay a good foundation for Immunotherapy.
From the above, it can be found that the treatment of Micro-Chinese Medicine combined with Immunotherapy has incomparable advantages of treating Polycystic Kidney Disease.
If you need more information about Polycystic Kidney Disease (PKD) and its treatments, please leave us a message or send email to kidney-treatment@hotmail.com.
Due to the strong compensatory ability, kidney can operate normally in the early stage of Kidney Disease. For this reason, many Polycystic Kidney Disease (PKD) patients seldom have obvious symptoms in early stage, which is also the reason why the disease is always neglected by most patients. Therefore, when patients are tested out this disease, most of their kidneys have been already injured seriously.
China Shijiazhuang Kidney Disease Hospital has developed a distinctive treatment, Micro-Chinese Medicine Osmotherapy combined with Immunotherapy, to treat Polycystic Kidney Disease (PKD). It has been proved by clinical practice that this treatment has an excellent effect on treating Polycystic Kidney Disease (PKD) indeed.
Micro-Chinese Medicine Osmotherapy is developed on the basis of Traditional Chinese Medicine. It has solved the problems of less effective absorption and low effect process in Traditional Chinese Medicine. Micronized Chinese Medicine is so tiny that it can permeate into renal lesions by an external application on kidney region on patients’ back. After entering into patients’ body, Micro-Chinese Medicine can shrink existing cysts, reduce cyst fluid secretion and block Renal Fibrosis by improving kidney blood circulation and inhibiting activity of epithelial cells on cyst wall, which can repair injured kidney radically. Though Micro-Chinese Medicine can repair kidney effectively, it can not create new healthy nephron. Therefore, our hospital adopts Immunotherapy to cover this shortage.
Immunotherapy can differentiate into necessary cells that injured tissue needs and repair injured kidney at the same time, so as to get maximum effect with minimum injury. This is in accordance with Micro-Chinese Medicine Osmotherapy.
Besides the advantages of Micro-Chinese Medicine Osmotherapy mentioned above, another important point should be mentioned is that some compositions of Micro-Chinese Medicine Osmotherapy can play a guiding role after Immunotherapy are transfused into patients’ body, which can lay a good foundation for Immunotherapy.
From the above, it can be found that the treatment of Micro-Chinese Medicine combined with Immunotherapy has incomparable advantages of treating Polycystic Kidney Disease.
If you need more information about Polycystic Kidney Disease (PKD) and its treatments, please leave us a message or send email to kidney-treatment@hotmail.com.
Abdominal Masses of Polycystic Kidney Disease (PKD) Patients
Why abdominal masses can be tested out among Polycystic Kidney Disease (PKD)
patients? Generally speaking, Adult Polycystic Kidney Disease which is autosomal
dominant inheritance is mainly caused by various sized cysts formed in renal
parenchyma. When cysts are still few and small, kidney volume can be normal.
With cysts growing and increasing, kidney volume increases at the same time. The
largest sick kidney may be more than 40cm and heavier than 8kg. Bilateral
kidneys can enlarge to asymmetrical sizes. With kidney enlarging, related
symptoms and functions aggravate gradually. The symptom of abdominal masses of
Polycystic Kidney Disease is mainly caused by enlarged kidneys. When kidney
enlarges to certain degree, masses can be touched on abdomen. 50% to 80%
Polycystic Kidney Disease (PKD) patients can be touched abdominal masses on
bilateral abdomen, and 15% to 30% patients can have unilateral abdominal masses.
When touched, kidney shows close texture with nodular shape, moving with breath.
Pressing pain can be felt if there is complicated infection.
When Polycystic Kidney Disease (PKD) patients get abdominal masses, they should go to hospital for a whole body check with the purpose of observing illness condition. Active and timely treatment is the best choice for Polycystic Kidney Disease (PKD) patients.
Micro-Chinese Medicine Osmotherapy which is an effective treatment of Polycystic Kidney Disease (PKD) is suggested to PKD patients. This treatment can treat Polycystic Kidney Disease (PKD) starting with shrinking cysts and reduce cyst fluid secretion by improving kidney blood circulation and inhibiting cyst growing. After many years of practice, this treatment has gained excellent effect in clinical treatment process.
When Polycystic Kidney Disease (PKD) patients get abdominal masses, they should go to hospital for a whole body check with the purpose of observing illness condition. Active and timely treatment is the best choice for Polycystic Kidney Disease (PKD) patients.
Micro-Chinese Medicine Osmotherapy which is an effective treatment of Polycystic Kidney Disease (PKD) is suggested to PKD patients. This treatment can treat Polycystic Kidney Disease (PKD) starting with shrinking cysts and reduce cyst fluid secretion by improving kidney blood circulation and inhibiting cyst growing. After many years of practice, this treatment has gained excellent effect in clinical treatment process.
2016年8月27日星期六
New Treatment of Renal Fibrosis
After many years of scientific and clinical research, China Shijiazhuang Kidney Disease Hospital has developed Micro-Chinese Medicine Osmotherapy which
is a great breakthrough of blocking Renal Fibrosis. Based on prescriptions of
Traditional Chinese Medicine, special effect of Micro-Chinese Medicine
Osmotherapy was found in application process of micronized Chinese Medicine.
Though clinical observation, it is found that Micro-Chinese Medicine Osmotherapy
has several disadvantages of quick recovery, long-lasting effect and less
recurrence in the process of treating poisoning symptoms of Kidney Disease
patients. In further observation, micronized Chinese Medicine contains massive
active substances which have the following characteristics and functions:
Firstly, function of eliminating activity of nephrotoxic factors: after entering into patients’ body, active substances of Chinese Medicine can eliminate activities of factors that can cause Renal Fibrosis. These substances can also promote phenotype reversion of injured renal cells. Besides, active substances can block Renal Fibrosis caused by nephrotoxic factors and other pathogenic factors, preventing kidney being injured further.
Secondly, function of speeding up Myofibroblast apoptosis: Active substances can combined with immune complex and Myofibroblast closely and eliminate them in order to prevent them synthesizing collagen which is difficult to be degraded.
Thirdly, function of degrading Extracellular Matrix: active substances can improve secretion of degrading enzymes of body connective tissue and active the function of these degrading enzymes. Finally, it can reduce formation of Extracellular Matrix.
Fourthly, function of improving injured kidney recovery: active substances of Chinese Medicine can provide beneficial environment for kidney recovery through methods of dilating renal arteries at all levels, improving kidney local microcirculation and relieve the condition of renal ischemia. Micronized Chinese Medicine contains rich vitamins, amino acids and trace elements, all of which are necessary for kidney recovery and improve the process of kidney recovery. Besides, active substances can promote synthesis of sulfate heparin on glomerular basement membrane and inhibit sulfate heparin degradation. Meanwhile, these active substances can repair charge barrier of glomerulus and recover renal function gradually.
Firstly, function of eliminating activity of nephrotoxic factors: after entering into patients’ body, active substances of Chinese Medicine can eliminate activities of factors that can cause Renal Fibrosis. These substances can also promote phenotype reversion of injured renal cells. Besides, active substances can block Renal Fibrosis caused by nephrotoxic factors and other pathogenic factors, preventing kidney being injured further.
Secondly, function of speeding up Myofibroblast apoptosis: Active substances can combined with immune complex and Myofibroblast closely and eliminate them in order to prevent them synthesizing collagen which is difficult to be degraded.
Thirdly, function of degrading Extracellular Matrix: active substances can improve secretion of degrading enzymes of body connective tissue and active the function of these degrading enzymes. Finally, it can reduce formation of Extracellular Matrix.
Fourthly, function of improving injured kidney recovery: active substances of Chinese Medicine can provide beneficial environment for kidney recovery through methods of dilating renal arteries at all levels, improving kidney local microcirculation and relieve the condition of renal ischemia. Micronized Chinese Medicine contains rich vitamins, amino acids and trace elements, all of which are necessary for kidney recovery and improve the process of kidney recovery. Besides, active substances can promote synthesis of sulfate heparin on glomerular basement membrane and inhibit sulfate heparin degradation. Meanwhile, these active substances can repair charge barrier of glomerulus and recover renal function gradually.
What Should Patients with Polycystic Kidney Disease Care About
It is rare to happen for Polycystic Kidney Disease (PKD) in the clinical, and
Polycystic Kidney Disease (PKD) is a hereditary disease which may occur in any
ages, usually this disease has a family history. Polycystic Kidney Disease (PKD)
patients must do thoughtful jobs to prevent its occurrence usually. Then what
should Polycystic Kidney Disease (PKD) patients do to prevent this disease? What
is helpful for its treatment and recovery? The below are some instructions:
1. Controlling the blood pressure
Most of Polycystic Kidney Disease (PKD) patients have Hypertension before renal function damage, it is regarded that Polycystic Kidney Disease (PKD) has attacked already. The occurrence of Hypertension can accelerate the damage of renal function. Meanwhile, Hypertension can cause cardiovascular lesion, and severe complications like stoke caused by Cerebral Hemangioma. Therefore, to manage blood pressure controlling is vital to prevent complications and defer the aggravation of renal function.
2. Controlling the diet
Reasonable diet for Polycystic Kidney Disease (PKD) patients is very important to control the aggravation of renal function damage. It is advisable to take diet with low salt, 2-3 g every day, patients should eat little food with Potassium and Phosphor and eat more food with low fat, low protein and take food rich in vitamins and crude fiber, keep defecation unobstructed.
3. Preventing cold
Polycystic Kidney Disease (PKD) patients are painful really because this disease has some differences with other Kidney Diseases. Polycystic Kidney Disease (PKD) is a hereditary disease in life, that is, this disease will haunt patients in his whole life. The objective reality that swollen cysts grow increasingly can not be evaded, even though you give much attention to it and family members provide you so much care. At this time, if patients suffer from cold, especially repetitive cold, the damage of renal function can be aggravated. That can speed up the damage of renal function.
4. Preventing trauma
With cysts swelling increasingly, cyst internal pressure will be enforced constantly, which impels the kidneys enlarge and adds enterocoelia internal pressure. Any slight trauma like sprain, bumping, falls etc can add enterocoelia internal pressure. External forces and wounds shock swelling cysts directly so as to make the cysts with high internal pressure rupture and bleed, which is readily to induce infection.
1. Controlling the blood pressure
Most of Polycystic Kidney Disease (PKD) patients have Hypertension before renal function damage, it is regarded that Polycystic Kidney Disease (PKD) has attacked already. The occurrence of Hypertension can accelerate the damage of renal function. Meanwhile, Hypertension can cause cardiovascular lesion, and severe complications like stoke caused by Cerebral Hemangioma. Therefore, to manage blood pressure controlling is vital to prevent complications and defer the aggravation of renal function.
2. Controlling the diet
Reasonable diet for Polycystic Kidney Disease (PKD) patients is very important to control the aggravation of renal function damage. It is advisable to take diet with low salt, 2-3 g every day, patients should eat little food with Potassium and Phosphor and eat more food with low fat, low protein and take food rich in vitamins and crude fiber, keep defecation unobstructed.
3. Preventing cold
Polycystic Kidney Disease (PKD) patients are painful really because this disease has some differences with other Kidney Diseases. Polycystic Kidney Disease (PKD) is a hereditary disease in life, that is, this disease will haunt patients in his whole life. The objective reality that swollen cysts grow increasingly can not be evaded, even though you give much attention to it and family members provide you so much care. At this time, if patients suffer from cold, especially repetitive cold, the damage of renal function can be aggravated. That can speed up the damage of renal function.
4. Preventing trauma
With cysts swelling increasingly, cyst internal pressure will be enforced constantly, which impels the kidneys enlarge and adds enterocoelia internal pressure. Any slight trauma like sprain, bumping, falls etc can add enterocoelia internal pressure. External forces and wounds shock swelling cysts directly so as to make the cysts with high internal pressure rupture and bleed, which is readily to induce infection.
2016年8月24日星期三
Treatment of Complications of Polycystic Kidney Disease
A series of complications may occur, if no immediate or no proper treatment
conducted during the attack of Polycystic Kidney Disease (PKD). In this case,
complications should be treated immediately and the chief methods of treatment
Polycystic Kidney Disease (PKD) compose of following kinds:
Firstly, Cysts Decortication
This treatment can reduce cysts pressure to renal parenchyma, and protect most of the remaining nephrons from being squeezed and further damage, which improve the renal ischemia and recover part of the renal function so as to defer the progression of disease. The crux to succeed in operation is to conduct operation as early as possible, eliminate cysts’ pressure thoroughly, and not to leave alone those small and in-depth cysts’ eradication. Bilateral kidneys should be operated and the interval time between two operations is over half a year. It is meaningless to take this approach, if Renal Failure has occurred to patients, say, Azotemia and Uremia, because operation trauma can aggravate the disease.
Secondly, Treatment of Hematuria
In case of Hematuria, patients should decrease activities or stay in bed, in addition to ascertaining the etiology and treatment. Patients who have taken dialysis or are to get dialysis can adopt operation of renal arterial embolism, if Hematuria reoccurs severely and can not be controlled
Thirdly, General Treatment
Most patients need not to change their life style and restrict their activities. However, patients with obvious swollen cysts should pay attention to preventing abdominal trauma, so as to avoid cyst rupture. Corresponding treatment should be conducted once Renal Failure and Uremia occurs to Patients.
Fourthly, Treatment of Hypertension
The activation of Renal ischemia and renin-angiotension-aldosterone system is the main reason to cause Hypertension, in this case, hypotensive agents can be applied.
Fifthly, Dialysis and Transplant
Dialysis can be conducted immediately if patients developed into End Stage Renal Failure. And hemoialysis is their first choice. The survival rate of cysts’ transplant is similar to other transplant, but the transplant effect can be affected with other complications, which increases the difficulty to handle after the transplant.
Sixthly, Treatment of Urinary Tract Stones
It can be handled as per the position and size of urinary tract stones.
Seventhly, Treatment of Infection
Infection of renal parenchyma and cysts internal infection are the main types. Usually combined antibiotics are adopted to treat them usually.
Eighthly, Chinese medicine
Reportedly, Chinese medicine with effect to spleen and improve urine can defer the progression of disease.
Firstly, Cysts Decortication
This treatment can reduce cysts pressure to renal parenchyma, and protect most of the remaining nephrons from being squeezed and further damage, which improve the renal ischemia and recover part of the renal function so as to defer the progression of disease. The crux to succeed in operation is to conduct operation as early as possible, eliminate cysts’ pressure thoroughly, and not to leave alone those small and in-depth cysts’ eradication. Bilateral kidneys should be operated and the interval time between two operations is over half a year. It is meaningless to take this approach, if Renal Failure has occurred to patients, say, Azotemia and Uremia, because operation trauma can aggravate the disease.
Secondly, Treatment of Hematuria
In case of Hematuria, patients should decrease activities or stay in bed, in addition to ascertaining the etiology and treatment. Patients who have taken dialysis or are to get dialysis can adopt operation of renal arterial embolism, if Hematuria reoccurs severely and can not be controlled
Thirdly, General Treatment
Most patients need not to change their life style and restrict their activities. However, patients with obvious swollen cysts should pay attention to preventing abdominal trauma, so as to avoid cyst rupture. Corresponding treatment should be conducted once Renal Failure and Uremia occurs to Patients.
Fourthly, Treatment of Hypertension
The activation of Renal ischemia and renin-angiotension-aldosterone system is the main reason to cause Hypertension, in this case, hypotensive agents can be applied.
Fifthly, Dialysis and Transplant
Dialysis can be conducted immediately if patients developed into End Stage Renal Failure. And hemoialysis is their first choice. The survival rate of cysts’ transplant is similar to other transplant, but the transplant effect can be affected with other complications, which increases the difficulty to handle after the transplant.
Sixthly, Treatment of Urinary Tract Stones
It can be handled as per the position and size of urinary tract stones.
Seventhly, Treatment of Infection
Infection of renal parenchyma and cysts internal infection are the main types. Usually combined antibiotics are adopted to treat them usually.
Eighthly, Chinese medicine
Reportedly, Chinese medicine with effect to spleen and improve urine can defer the progression of disease.
2016年8月23日星期二
Hypertension and Polycystic Kidney Disease (PKD)
What is the sophisticated relationship between Hypertension and Polycystic Kidney Disease? Everybody knows that Hypertension is easy to cause
cerebrovascular disease and cardiovascular disease. Actually, Hypertension is
also closely related with Kidney Disease. Well then, what is the relationship
between Hypertension and Polycystic Kidney Disease (PKD)?
Medical research has shown that Hypertension usually causes renal injury, and contrarily, renal injury can also cause Hypertension. Both of them affect each other, resulting in vicious circulation easily. Most patients pay less attention on treating Polycystic Kidney Disease (PKD) after they were told that this disease is a kind of genetic disease. Usually for this reason, this disease always develops into the most serious stage of Kidney Disease, Uremia stage, unconsciously.
Polycystic Kidney Disease has a progressive development and usually occurs among adult people, with abnormal proliferation of renal tubular epithelial cells as its dominant characteristic. When renal tubular epithelial cells turn into cystic epithelial cells, they begin to have secreting ability and keep secreting fluid more and more, but there is no normal way to excrete increasing fluid. For this reason, cysts grow bigger and bigger with time passing. When cysts grow to some certain degree, they will replace healthy renal tissue. Then renal function declines gradually. At this moment, Hypertension and routine urine test abnormality appear in clinical observation.
The medicine that Polycystic Kidney Disease (PKD) patients take may even cause damage to injured kidney due to nephrotoxicity. Besides, most patients who suffer from Hypertension usually go to hospital for cardiovascular tests directly instead of kidney routine tests. Therefore, kidney injury can not be found in time, which is one of main causes of Uremia.
If blood pressure can not be controlled effective, it can damage kidney. Meanwhile, Hypertension may develop into Hypertensive Nephropathy. Kidney is an internal organ consisting of countless micro blood vessels, and kidney internal mini arteries may be hardened if Hypertension can not be controlled in a long term. This is also the reason why most Hypertension patients have kidney injury. If such injury can not be treated in time, it will cause glomerular sclerosis, renal interstitial fibrosis, or even Renal Insufficiency and Uremia finally.
Contrarily, Polycystic Kidney Disease (PKD) can also cause Hypertension. The more serious kidney injury is, the high blood pressure is. In late stage of Renal Failure, 80% patients get obvious Hypertension.
Medical research has shown that Hypertension usually causes renal injury, and contrarily, renal injury can also cause Hypertension. Both of them affect each other, resulting in vicious circulation easily. Most patients pay less attention on treating Polycystic Kidney Disease (PKD) after they were told that this disease is a kind of genetic disease. Usually for this reason, this disease always develops into the most serious stage of Kidney Disease, Uremia stage, unconsciously.
Polycystic Kidney Disease has a progressive development and usually occurs among adult people, with abnormal proliferation of renal tubular epithelial cells as its dominant characteristic. When renal tubular epithelial cells turn into cystic epithelial cells, they begin to have secreting ability and keep secreting fluid more and more, but there is no normal way to excrete increasing fluid. For this reason, cysts grow bigger and bigger with time passing. When cysts grow to some certain degree, they will replace healthy renal tissue. Then renal function declines gradually. At this moment, Hypertension and routine urine test abnormality appear in clinical observation.
The medicine that Polycystic Kidney Disease (PKD) patients take may even cause damage to injured kidney due to nephrotoxicity. Besides, most patients who suffer from Hypertension usually go to hospital for cardiovascular tests directly instead of kidney routine tests. Therefore, kidney injury can not be found in time, which is one of main causes of Uremia.
If blood pressure can not be controlled effective, it can damage kidney. Meanwhile, Hypertension may develop into Hypertensive Nephropathy. Kidney is an internal organ consisting of countless micro blood vessels, and kidney internal mini arteries may be hardened if Hypertension can not be controlled in a long term. This is also the reason why most Hypertension patients have kidney injury. If such injury can not be treated in time, it will cause glomerular sclerosis, renal interstitial fibrosis, or even Renal Insufficiency and Uremia finally.
Contrarily, Polycystic Kidney Disease (PKD) can also cause Hypertension. The more serious kidney injury is, the high blood pressure is. In late stage of Renal Failure, 80% patients get obvious Hypertension.
How Does Chinese Medicine Doctor Make A Diagnosis
“Four methods of diagnosis” of Chinese Medicine was known as looking,
listening, questioning, and pulse-taking. Human body is an organic integration,
and local pathological change can affect the whole body. For example,
pathological changes of internal organs can be reflected by face as well as arms
and legs. Therefore, through the four diagnosing methods of looking, listening
and smelling, questioning, and pulse-taking, doctors can find symptoms of each
aspect, knowing the causes, nature and internal connection of the disease, which
make contribution to choose treatment based on syndrome differentiation in next
step.
Method of looking: this means doctors use eyes to observe patients whole body and local change of appearance and figure. Through massive medical practices, Chinese Medicine realized that the outside part of body, especially face and tongue, is related with internal organs closely. Once internal organs are sick, there must be related reflection appeared in body surface. Therefore, through the method of looking, doctors can know the internal pathological change of internal organs. For example, though some patients are looked like to have more serious illness condition, they still have exuberated Qi if they have good spirit. Such patients can have a better therapeutic effect than those who have gloomy spirit condition. Colors of face can also show pathological changes of different internal organs. Green, red, yellow, white, and black correspond to liver, heart, spleen, lung, and kidney. If face color looks green, it may refer to liver pathological change, while yellow may refer to pathological change of spleen.
Method of listening and smelling: this means that doctors listen to patients’ voice and breathe by ears and smell patients’ body or patients’ excrement. All these are valuable to distinguish patients’ illness condition.
Method of questioning: it is very important in clinical practice of Chinese Medicine. When the disease happens? What are the causes and process of this disease? Do patients have any other disease before? Where is the painful position? How about patients’ living diet habit? All these factors related with disease can be get through asking patients or their relatives.
Method of pulse-taking: this means touching patients’ body with hands. Doctors touch or press some certain parts of patients in order to know more about illness condition. It can be divided into pulse-taking and palpation.
These four methods are an integrated whole, and they must be combined organically in clinical prognosis. Besides, disease usually has complex manifestations and the disease and its related manifestations are different. At this moment, doctors’ experience is important to make a correct diagnosis.
Method of looking: this means doctors use eyes to observe patients whole body and local change of appearance and figure. Through massive medical practices, Chinese Medicine realized that the outside part of body, especially face and tongue, is related with internal organs closely. Once internal organs are sick, there must be related reflection appeared in body surface. Therefore, through the method of looking, doctors can know the internal pathological change of internal organs. For example, though some patients are looked like to have more serious illness condition, they still have exuberated Qi if they have good spirit. Such patients can have a better therapeutic effect than those who have gloomy spirit condition. Colors of face can also show pathological changes of different internal organs. Green, red, yellow, white, and black correspond to liver, heart, spleen, lung, and kidney. If face color looks green, it may refer to liver pathological change, while yellow may refer to pathological change of spleen.
Method of listening and smelling: this means that doctors listen to patients’ voice and breathe by ears and smell patients’ body or patients’ excrement. All these are valuable to distinguish patients’ illness condition.
Method of questioning: it is very important in clinical practice of Chinese Medicine. When the disease happens? What are the causes and process of this disease? Do patients have any other disease before? Where is the painful position? How about patients’ living diet habit? All these factors related with disease can be get through asking patients or their relatives.
Method of pulse-taking: this means touching patients’ body with hands. Doctors touch or press some certain parts of patients in order to know more about illness condition. It can be divided into pulse-taking and palpation.
These four methods are an integrated whole, and they must be combined organically in clinical prognosis. Besides, disease usually has complex manifestations and the disease and its related manifestations are different. At this moment, doctors’ experience is important to make a correct diagnosis.
2016年8月22日星期一
What Is the Characteristic of Cysts’ Growth in Polycystic Kidney Disease
For Adult Polycystic Kidney Disease,cysts’ growth features as below
aspects:
I. Different disease time
Different individuals of Polycystic Kidney Disease (PKD) get attacked at different time, because of different environment, constitution and genes. Even though patients from the same family in which family members usually have the same assignment of genes, they are attacked at different time. It is also reported that the attacking age of Polycystic Kidney Disease (PKD) tends to be younger in each subsequent generation, that is, children get disease at earier time than their parents.
II. The Number of cysts increases gradually
According to the evaluation, about 1%-5% of nephrons produce cysts under the function of Polycystic Kidney Disease (PKD) genes. Each kidney has 100-200 million of nephrons, so we could calculate how many cysts will occur. But all the potential cysts occur successively other than at the same time under various conditions. The number of cysts grows rapidly once the appearance of cyst.
III. Grown cysts enlarge continuously
Hyperplasia occurs as cystic genes affect epithelial cell of kidney tubule, and it can block the lumen of kidney tubule. Besides, cystic genes can change the status of basement membrane of kidney tubule. There are two reasons which arouse formed cyst to enlarge increasingly. On one hand, primary urine filtrated by glomerulus can enter into cysts, on the other, epithelial cell of cysts secrete liquid continuously.
IV. Cysts grow at an unbalanced speed
Due to infection, bad diet, sentimental disorder, toxic touchment, improper activity, fatigue and other factors, two stages of cyst development, active phase and stable phase, appears. This means that cyst can grow fast sometimes, but stably and slowly in some other period.
I. Different disease time
Different individuals of Polycystic Kidney Disease (PKD) get attacked at different time, because of different environment, constitution and genes. Even though patients from the same family in which family members usually have the same assignment of genes, they are attacked at different time. It is also reported that the attacking age of Polycystic Kidney Disease (PKD) tends to be younger in each subsequent generation, that is, children get disease at earier time than their parents.
II. The Number of cysts increases gradually
According to the evaluation, about 1%-5% of nephrons produce cysts under the function of Polycystic Kidney Disease (PKD) genes. Each kidney has 100-200 million of nephrons, so we could calculate how many cysts will occur. But all the potential cysts occur successively other than at the same time under various conditions. The number of cysts grows rapidly once the appearance of cyst.
III. Grown cysts enlarge continuously
Hyperplasia occurs as cystic genes affect epithelial cell of kidney tubule, and it can block the lumen of kidney tubule. Besides, cystic genes can change the status of basement membrane of kidney tubule. There are two reasons which arouse formed cyst to enlarge increasingly. On one hand, primary urine filtrated by glomerulus can enter into cysts, on the other, epithelial cell of cysts secrete liquid continuously.
IV. Cysts grow at an unbalanced speed
Due to infection, bad diet, sentimental disorder, toxic touchment, improper activity, fatigue and other factors, two stages of cyst development, active phase and stable phase, appears. This means that cyst can grow fast sometimes, but stably and slowly in some other period.
Clinical Care of Patients with Polycystic Kidney Disease in Different Stages
For patientts with Polycystic Kidney Disease (PKD), they need different cares
in different stages. And the care to them is directly related with the
progression of treatment. Regard with the clinical care for PKD patients, we
give you instructions as below.
I. Cares to PKD patients who have no renal function damage:
When PKD is figured out in the hospital check-up, doctors is obligatory to let patients know this disease is a hereditary disease and other related knowledge. As for PKD patients who are pregnant, they need to take an antenatal check after pregnancy; patients who have no renal function damage or other obvious symptoms need to take regular follow-up visit and learn the progression of renal function; patients should avoid collision and squeeze and do not take part in severe activities, and they should also prevent Hematuria and urinary tract infection, take reasonable diet and have a regular life. Besides, it is also helpful to take proper exercises, combine rest and work, quit smoking and liquor and handle life and body correctly.
II. Cares to patients who is in renal function compensatory stage accompanying with Hypertension.
When the disease develops into compensatory stage, accompanying with Hypertension, patients can take hypotensive agents. Meanwhile, they should take diet with low salt and low fat, qualified protein. Patients should have more rest and prevent fatigue, cold, urinary and intestinal tract infection. Besides, patients should take renal function test and urine routine test regularly. Due to cysts growth, nephrons decrease gradually and renal function declines correspondingly. Cysts rupture and renal stone can cause bleeding within kidney, presenting as gross Hematuria which is usually fresh red or soy color. Blood is a nutritious fostering agent for inflammation, which may cause severe urinary tract infection. Therefore, patients should stay in bed and take antibotic to treat inflammation and stanch blood in early stage of bleeding.
III. Cares to patients who is in early or middle stage of Chronic Renal Failure
Patients should avoid taking nephrotoxic medicine, like Gentamycin, Kanamyci, Cefradine, Vancomycin and Indomethacin etc, These medicines can directely damage renal parenchyma and aggravate renal function because primary elements in most of these medicines are discharged through kidney. Renal excretion becomes slow as renal insufficiency happens. In other words, the dosage of medicine increases virtually. Therefore, it is advisable to reduce dosage or extend the interval time between drug administrations according to the extent of Renal Insufficiency.
IV. Cares to patients who is in End Stage Uremia
Due to the big volume of cysts, it is difficult for patients to take peritonial dialysis, so hemodialysis is mainly applied in patients with End Stage Uremia at present.
I. Cares to PKD patients who have no renal function damage:
When PKD is figured out in the hospital check-up, doctors is obligatory to let patients know this disease is a hereditary disease and other related knowledge. As for PKD patients who are pregnant, they need to take an antenatal check after pregnancy; patients who have no renal function damage or other obvious symptoms need to take regular follow-up visit and learn the progression of renal function; patients should avoid collision and squeeze and do not take part in severe activities, and they should also prevent Hematuria and urinary tract infection, take reasonable diet and have a regular life. Besides, it is also helpful to take proper exercises, combine rest and work, quit smoking and liquor and handle life and body correctly.
II. Cares to patients who is in renal function compensatory stage accompanying with Hypertension.
When the disease develops into compensatory stage, accompanying with Hypertension, patients can take hypotensive agents. Meanwhile, they should take diet with low salt and low fat, qualified protein. Patients should have more rest and prevent fatigue, cold, urinary and intestinal tract infection. Besides, patients should take renal function test and urine routine test regularly. Due to cysts growth, nephrons decrease gradually and renal function declines correspondingly. Cysts rupture and renal stone can cause bleeding within kidney, presenting as gross Hematuria which is usually fresh red or soy color. Blood is a nutritious fostering agent for inflammation, which may cause severe urinary tract infection. Therefore, patients should stay in bed and take antibotic to treat inflammation and stanch blood in early stage of bleeding.
III. Cares to patients who is in early or middle stage of Chronic Renal Failure
Patients should avoid taking nephrotoxic medicine, like Gentamycin, Kanamyci, Cefradine, Vancomycin and Indomethacin etc, These medicines can directely damage renal parenchyma and aggravate renal function because primary elements in most of these medicines are discharged through kidney. Renal excretion becomes slow as renal insufficiency happens. In other words, the dosage of medicine increases virtually. Therefore, it is advisable to reduce dosage or extend the interval time between drug administrations according to the extent of Renal Insufficiency.
IV. Cares to patients who is in End Stage Uremia
Due to the big volume of cysts, it is difficult for patients to take peritonial dialysis, so hemodialysis is mainly applied in patients with End Stage Uremia at present.
2016年8月20日星期六
Consultation from Polycystic Kidney Disease (PKD) Patient
Patient: I have suffered from Polycystic Kidney Disease (PKD) for about ten
years and the largest cyst is 4cm. Now I have got more serious pain on waist and
higher creatinine than before. Doctors told me that if I do not accept
operation, this disease can develop into Uremia. However, my doctor also said
that operation can not treat my disease completely. Is it real? I am so scared.
Please give me some suggestions.
Expert Answer: 4cm is not small among cysts. Generally, your disease has already developed into Renal Insufficiency which is mainly caused by too much cystic pressure on renal tissue. You mentioned your creatinine is increasing. This always means your half of your kidneys is injured by cysts. The key of treating Polycystic Kidney Disease is to prevent it developing. Polycystic Kidney Disease is a kind of congenital genetic disease. It is usually found at the end stage and renal function decline is more common 10 years after this disease was found.
Well then, how to prevent this disease happening? Micro-Chinese Medicine Osmotherapy has its distinctive effect on block the process of this disease developing. This treatment can shrink cysts, which can reduce cystic pressure on renal parenchyma. Only by this way, glomerular ischemia and anoxia can be relived radically. Then Renal Fibrosis can be blocked, preventing this disease developing into Uremia Stage.
If you need more information about Polycystic Kidney Disease (PKD) and its treatment, please leave us a message or you can send an email to kidney-treatment@hotmail.com.
Expert Answer: 4cm is not small among cysts. Generally, your disease has already developed into Renal Insufficiency which is mainly caused by too much cystic pressure on renal tissue. You mentioned your creatinine is increasing. This always means your half of your kidneys is injured by cysts. The key of treating Polycystic Kidney Disease is to prevent it developing. Polycystic Kidney Disease is a kind of congenital genetic disease. It is usually found at the end stage and renal function decline is more common 10 years after this disease was found.
Well then, how to prevent this disease happening? Micro-Chinese Medicine Osmotherapy has its distinctive effect on block the process of this disease developing. This treatment can shrink cysts, which can reduce cystic pressure on renal parenchyma. Only by this way, glomerular ischemia and anoxia can be relived radically. Then Renal Fibrosis can be blocked, preventing this disease developing into Uremia Stage.
If you need more information about Polycystic Kidney Disease (PKD) and its treatment, please leave us a message or you can send an email to kidney-treatment@hotmail.com.
Renal Tissue Infection in Polycystic Kidney Disease
What are the damages of renal tissue infection to Polycystic Kidney Disease
patients? Such infections usually refer to inflammation and infection caused by
cyst rupture or cyst fluid that permeates into renal tissue.
Polycystic Kidney Disease is a kind of genetic disease. According to the genetic features, it can be divided into Autosomal Dominant Polycystic Kidney Disease and Autosomal Recessive Polycystic Kidney Disease, and the former one is more common.
Cysts exist when patients were born. With time passing, it may occur and develop when patients become adults. Most patients are expressed by bilateral kidneys abnormality, with unequal pathological change.
Cysts with various sizes spread over the whole kidney. There are urinelike liquid in cysts. When there is bleeding or infection, cysts will show different shapes. When cysts grow into some certain degree, cyst rupture may happen, which can induce inflammation and infection.
Polycystic Kidney Disease patients should take anti-infection treatment in order to control inflammation. One point should be noted that inflammation in Polycystic Kidney Disease is related with cysts. Therefore, patients should accept treatment to control cyst growth and shrink cysts in order to prevent cyst rupture, which can avoid inflammation and infection effectively.
Combination of Chinese Medicine and Western Medicine is suggested to control cyst growth. Our hospital adopts Micro-Chinese Medicine Osmotherapy to treat Polycystic Kidney Disease. This treatment can repair injured renal inherent cells, block renal fibrosis and degrade Extracellular Matrix through methods of dilating blood vessel, anti-inflammation, anticoagulation and degradation. It has gained good effect in clinical practice.
If you need more information about Polycystic Kidney Disease (PKD) and its treatment, please leave us a message or you can send an email to kidney-treatment@hotmail.com
Polycystic Kidney Disease is a kind of genetic disease. According to the genetic features, it can be divided into Autosomal Dominant Polycystic Kidney Disease and Autosomal Recessive Polycystic Kidney Disease, and the former one is more common.
Cysts exist when patients were born. With time passing, it may occur and develop when patients become adults. Most patients are expressed by bilateral kidneys abnormality, with unequal pathological change.
Cysts with various sizes spread over the whole kidney. There are urinelike liquid in cysts. When there is bleeding or infection, cysts will show different shapes. When cysts grow into some certain degree, cyst rupture may happen, which can induce inflammation and infection.
Polycystic Kidney Disease patients should take anti-infection treatment in order to control inflammation. One point should be noted that inflammation in Polycystic Kidney Disease is related with cysts. Therefore, patients should accept treatment to control cyst growth and shrink cysts in order to prevent cyst rupture, which can avoid inflammation and infection effectively.
Combination of Chinese Medicine and Western Medicine is suggested to control cyst growth. Our hospital adopts Micro-Chinese Medicine Osmotherapy to treat Polycystic Kidney Disease. This treatment can repair injured renal inherent cells, block renal fibrosis and degrade Extracellular Matrix through methods of dilating blood vessel, anti-inflammation, anticoagulation and degradation. It has gained good effect in clinical practice.
If you need more information about Polycystic Kidney Disease (PKD) and its treatment, please leave us a message or you can send an email to kidney-treatment@hotmail.com
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