What are the causes of high level of serum creatinine? Creatinine is the
metabolic productions of muscle in human body and 20g muscle can generate 1mg
creatinine. Creatinine can be divided into serum creatinine (Scr) and urine
creatinine (Ucr). The creatinine is filtrated by glomerulus(the important
components of kidney) to eliminate out of human body. There are two sources of
Scr, one is the metabolic products of meat food in human body, the other one is
the metabolic products of muscle in human body. When you have a stable intake of
meat food and the metabolic products of muscle are stable, the level of
creatinine won't change much. As for Ucr, it is the creatinine eliminated by the
urine after the filtration of glomerulus.
So what are the causes of the high level of serum creatinine? The patients of
kidney disease have the fluctuation of creatinine in clinical examinations. The
manifestation is that Scr is higher while the Ucr is lower.
The causes of the high level of Scr is complex. After the renal damage caused
by various pathogenesis, the shape of damaged renal inherent cells will change
and they will form the pathological change, which will stimulate the renal
fibroblasts to turn into muscle fibroblasts and stimulate the normal inherent
renal structure to form the same pathological change. Then the pathological
change expands form one unit to the whole kidney, from local to the whole, then
the damage develops into the renal damage period. At this time, for the
continuous damage of kidney, the renal function of eliminating waste will
decrease, which will cause the accumulation of creatinine and other toxin in
human body, then the Scr and BUN increase but Ucr decreases, at the same time
the glomerulus filtration rate decreases.
The increase of Scr is an important clinical symptom of kidney disease, on
the other hand, the accumulation of Scr in human body will damage the kidney and
other organs in return. Therefor, we must adopt effective methods to control the
level of creatinine positively. However, the basic method should proceed with
the pathogenesis of kidney disease and treat the kidney disease fundamentally.
As for the treatment of kidney disease, at present, the most effective treatment
of PKD is combining traditional Chinese medicine with Western medicine. Now a
brand new therapy has been developed out by Shijiazhuang Kidney Disease
Hospital-- Micro-Chinese Medicine Osmotherapy. This therapy adopts the most
advanced technology in the world to micronize the traditional Chinese medicine
into medicine powder,which has strong ability of permeability and can access to
kidney directly by external application. By this method, the effects of Chinese
medicine can be accelerated and enhanced. Besides, combining with Western
medicine, this therapy has achieved rather good effects in clinical. If you have
any other questions or want to learn more about Micro-Chinese Medicine
Osmotherapy, please contact our experts on-line.
