Acute renal failure is a syndrome. For a variety of reasons cause, glomerular filtration rate decreased rapidly below 50% of normal, blood urea nitrogen and serum creatinine increased rapidly and cause water substance disorders and disorders of acid-power balance base and symptoms of acute uremia. Acute renal failure is observed in disease subjects, acute renal failure and chronic renal failure are different, such as early diagnosis and timely rescue, renal function is fully restored, such as delayed treatment may be fatal . The prognosis of the primary disease, age, diagnosis and treatment sooner or later, if you want to combine multiple organ failure, and other factors.
Clinical manifestations
1. Oliguria: (1) Three low (sodium, calcium, reduced pH), three high (potassium, phosphorus, creatinine increased), edema (2) uremic symptoms may include nausea, vomiting, gastrointestinal bleeding, difficulty. breathing, coughing, chest pain, hypertension, heart failure, drowsiness, mental confusion, tremors and epileptic seizures, anemia and bleeding tendency etc. (3) Infection according to the site of infection to produce symptoms.
2. The time of much urine: The function of the kidneys failed to restore, blood urea and creatinine continues to rise, and prone to dehydration, infection, hypokalemia, gastrointestinal bleeding etc.
3. Convalescence: blood urea nitrogen and creatinine near normal, urine output gradually returned to normal, the role of glomerular filtration rate in 3-12 months more back to normal.
Differential Diagnosis
based diagnosis
1. There shock or hemolysis, drug toxicity or intravascular allergies.
2. By correcting or exclude acute hypovolemia, dehydration, urinary tract obstruction, urine remains ≤ 17 / ml / hu urine remains ≤ 400 / ml / 24h.
3. Specific gravity of urine in 1015 or less, and even set to 1,010.
4. Abrupt onset and increasing azotemia.
5. The urine osmolality <350mOsm / Kg.H2O, urinary sodium> 40 mmol / L.
6. Except prerenal and postrenal azotemia little or no urine.
Above mentioned are the clinical features and differential diagnosis of acute renal failure? If you are interested in our items, still pay attention to us please! We articles on various diseases of kidneys, include rudimetos, symptoms, treatment, diet and fitness has all the information? If you have any problem, you can consult our experts online or leave message below!
