2014年12月25日星期四

The causes of proteinuria

(一) Kidney Proteinuria

1. Proteinuria glomerular

Common in acute glomerulonephritis, various types of chronic glomerulonephritis, IgA nephritis, nephritis hides.

Common secondary ect as renal lupus, autoimmune disorders, diabetic nephropathy, purpura nephritis, renal arteriosclerosis ect.

Common metabolic disorders in gout kidney

According to the degree of filtration membrane disease injury and proteinuria is divided into two components:

Proteinuria selective ①: mainly albumin, and a small amount of low molecular weight proteins, no large proteins Urine (IgG, IgA, IgM, C3, C4), semi-quantitative especially in +++ ~ ++++ typical disease is nephrotic syndrome.

② Proteinuria nonselective: Description fracture of the glomerular capillary wall severely injured in urine is large molecular weight proteins such as immunoglobulins, complement, the average molecular weight and low molecular weight protein albumin in urinary protein, immunoglobulin / albumin ratio> 0.5, semiquantitative + ~ ++++, quantification between 0.5 ~ 3.0g / 24h, common in primary glomerular disease as rapidly progressive glomerulonephritis, chronic nephritis, membranous glomerulonephritis and mesangial proliferative diseases ect.y secondary glomerular nephritis as diabetes, lupus nephritis ect. The emergence nonselective proteinuria bad prognosis.

Vigorous exercise, long march, high temperature environment, fever, cold environment, nervousness, congestive heart failure ect, also appear proteinuria.

2. tubular proteinuria:

The most common variety of causes interstitial nephritis, renal vein thrombosis, renal artery thrombosis, salts of heavy metal poisoning ect.

Proteinuria in renal tissue:

Also known as secretory proteinuria. Since during the formation of urine, renal metabolism of protein in the urine caused by infiltration.

(二) Proteinuria no renal

proteinuria humoral

Also known as overflow proteinuria, such as multiple myeloma.

proteinuria organization

As protein in urine cancer, viral infection of host proteins produced ect.

Lower urinary tract mixed with proteinuria cause proteinuria

Common urinary tract infections, urinary tract epithelial cells and peeling of the urinary tract secrete mucin.

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