NS complications is an important factor affecting prognosis and long-term patients, should actively monitor.
1. Infection
Usually in hormone therapy without antibiotics to prevent infection, if not prophylactically only achieve, but can induce fungal superinfection. Once infected, the timely use of sensitive pathogens, potent nephrotoxic antibiotics and no active treatment, there is a clear focus of infection should be removed as soon as possible. Reduction should be considered in severe infections difficult to control or disable the hormone, subject to the specific circumstances of the patient decide.
2. Complications of thrombotic and embolic
Generally, when the serum albumin of less than 20 g / L (idiopathic membranous nephropathy is less than 25 g / L) anticoagulant therapy may be administered heparin (LMWH can also be used) or subcutaneous injection oral.La warfarin anticoagulation can complement both antiplatelet drugs such as aspirin or dipyridamole produced via oral.Se thrombosis, embolism, as soon as possible (within 6 hours of the best, but still expected in 3 valid days) give urokinase systemic or local or streptokinase thrombolysis, with anticoagulant therapy, anticoagulation must be consistently applied generally over six months. Anticoagulants and thrombolytics should avoid overdoses cause bleeding.
3. Acute renal failure
NS concurrent acute renal failure can there be life threatening if not handled properly, if given the proper and timely treatment, it is expected that most patients recover. It may take the following measures:
(1) Loop diuretics: Still valid for loop diuretics should be greater quantities than seek the renal tubular obstruction.
(2) Hemodialysis: Diuretic is invalid, and has come to the indications for dialysis, hemodialysis should be given in order to sustain life, and supplementary products suitable plasma after dehydration, to reduce edema renal interstitial.
(3) The treatment of the primary disease: Due to its pathological type more are minimal change nephropathy, should be actively treated.
(4) alkaline urine: Alkaline sodium bicarbonate in the urine can be taken orally to reduce tube formation.
4. Disorder protein and fat metabolism
Before referral NS is often difficult to fully correct before metabolic disorders, but the diet should be adjusted to the amount of fat and protein and structure, and strive to reduce the influence of metabolic disturbances to a minimum. Currently, many drugs available for the treatment of metabolic protein and fat metabolism. As ACEI receptor antagonists and angiotensin Ⅱ can reduce proteinuria, some studies suggest that astragalus may promote liver synthesis of albumin, and can therefore reduce the role of hyperlipidemia. cholesterol lowering agents can choose based cholesterol lowering hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase, such as lovastatin and other statins, clofibrate or lower triglycerides based on categories such as fenofibrate and so on. NS remission natural ease hyperlipidemia is no need to continue drug treatment.
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