Minimal change disease is a subtype of nephrotic syndrome. This most commonly occurs in children than in adults. What is the treatment for minimal change disease nephrotic syndrome?
Minimal change disease nephrotic syndrome
Kidney filtration membrane is constructed as a sieve to allow molecular waste products pass through the blood, but retains large molecular useful substances in the body such as proteins. However, nephrotic syndrome, the membrane is damaged. As a result, a large amount of proteins in urine leakage from blood. Minimal change disease gets its name because this damage is not visible in regular microscope. It can only be seen under an electron microscope. It is the most common cause of nephrotic syndrome in children, accounting for 80% of cases.
Treatment for minimal change disease nephrotic syndrome
Minimal change disease in children is not a difficult disease to manage. Corticosteroids can cure minimal change disease in most children. Some patients may need to stay on steroids to keep the disease in remission.
However, adults do not respond to steroids as well as children. May experience frequent relapses of the disease and become steroid dependent. If so, patients may do better with cytotoxic therapy instead of steroids. In addition, some medications such as ACE inhibitor drugs, diuretics, etc are commonly used to control symptoms of disease minimal change nephrotic syndrome. However, if patients do not respond well to conventional treatments, they must have an alternative treatment.
Alternative treatment for minimal change disease nephrotic syndrome
Immunotherapy is recommended to treat disease minimal change nephrotic syndrome. First, it can suppress the inflammatory response in kidneys to stop further deterioration of renal function mainly. Secondly, you can activate the self-healing system of the body to stimulate self-repair of damaged glomeruli. When kidney structure is repaired, protein loss will be controlled mainly. Minimal change disease is treated effectively and fundamentally.
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