Nephrotic syndrome can occur in both children and adult disease changes. Minimum is a type of disease categories and are commonly seen in children. What is the treatment for minimal change disease with frequent relapses?
Why minimal change disease relapse so often?
Minimal change disease may be primary and secondary. Primary means that the disease presents itself for no apparent reason. Secondary means that the disease is caused by another disease or condition such as infection, allergies, medications etc.
No matter it is primary or secondary, the general cause of minimal change disease is immune disorder. In proper condition, when the foreign harmful substances invade the body, the immune system produces antibodies to defeat them. However, when the immune system malfunctions, then the harmful substances are removed, the immune system will stop working. Excessive immune response can cause inflammation in the kidneys, which leads to scarring of glomeruli are kidney filters. As a result, a large number of escape protein in urine protein. Heavy in the urine may result in minimal change disease.
In general cases, patients have a remission after a period of treatment with steroids and have a good long-term prognosis.
However, if immunity is very weak, the abnormal immune response is likely to relapse when any trigger.
Treatment of minimal change disease with frequent relapses.
To treat essential minimal change disease and to stop relapses, immunotherapy to patients is recommended.
Immunotherapy has been used to treat various intractable diseases such as cancer and has proved highly effective in the clinic.
Immunotherapy can suppress abnormal inflammatory response of the kidney stop further immune renal damage.
In addition, you can correct disorders of the immune system and helps the body to restore normal immune systems. If so, the immune system returns to normal, in order to protect the body instead of attacking the kidneys. Therefore, small lesions primarily with frequent relapses will control.
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